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Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31.
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Europe PubMed Central
PMC publication ID
4237267
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25341040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
title
Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31
(English)
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Europe PubMed Central
PMC publication ID
4237267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25341040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
main subject
apoptotic process
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author
Sathish K. R. Padi
series ordinal
2
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Europe PubMed Central
PMC publication ID
4237267
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25341040%20AND%20SRC:MED&resulttype=core&format=json
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21 February 2020
author name string
Q Zhang
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1
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Europe PubMed Central
PMC publication ID
4237267
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25341040%20AND%20SRC:MED&resulttype=core&format=json
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21 February 2020
D J Tindall
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3
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4237267
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21 February 2020
B Guo
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4
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21 February 2020
publication date
23 October 2014
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Europe PubMed Central
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4237267
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retrieved
21 February 2020
published in
Cell Death and Disease
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Europe PubMed Central
PMC publication ID
4237267
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21 February 2020
volume
5
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4237267
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21 February 2020
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e1486
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retrieved
21 February 2020
copyright license
Creative Commons Attribution 4.0 International
start time
1 October 2014
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April 2022 Public Data File from Crossref
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0 references
cites work
MicroRNA-124 inhibits proliferation and induces apoptosis by directly repressing EZH2 in gastric cancer
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PubMed Central
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7 July 2018
Methyl jasmonate sensitizes human bladder cancer cells to gambogic acid-induced apoptosis through down-regulation of EZH2 expression by miR-101.
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Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes apoptosis resistance in leukaemia
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7 July 2018
Role of EZH2 in the growth of prostate cancer stem cells isolated from LNCaP cells
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Multifaceted role of EZH2 in breast and prostate tumorigenesis: epigenetics and beyond
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MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer
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7 July 2018
miR-101 inhibits autophagy and enhances cisplatin-induced apoptosis in hepatocellular carcinoma cells
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Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression
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7 July 2018
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
1 reference
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7 July 2018
Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.
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Targeting the enhancer of zeste homologue 2 in medulloblastoma.
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Myc enforces overexpression of EZH2 in early prostatic neoplasia via transcriptional and post-transcriptional mechanisms
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The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.
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7 July 2018
Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells
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7 July 2018
Aberrations of EZH2 in cancer
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7 July 2018
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis
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An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression
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7 July 2018
Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression
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PubMed Central
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7 July 2018
Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation
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7 July 2018
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
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7 July 2018
The miR-34 family in cancer and apoptosis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Patterns of microRNA expression characterize stages of human B-cell differentiation.
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7 July 2018
MicroRNAs: target recognition and regulatory functions
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7 July 2018
Activation of the enhancer of zeste homologue 2 gene by the human papillomavirus E7 oncoprotein
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Repression of E-cadherin by the polycomb group protein EZH2 in cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Roles of the EZH2 histone methyltransferase in cancer epigenetics
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
E2F6 negatively regulates ultraviolet-induced apoptosis via modulation of BRCA1.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Expression of the enhancer of zeste homolog 2 is correlated with poor prognosis in human gastric cancer.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
A pancreatic islet-specific microRNA regulates insulin secretion
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
MicroRNAs modulate hematopoietic lineage differentiation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
p300 in prostate cancer proliferation and progression.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
retrieved
7 July 2018
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
retrieved
7 July 2018
The polycomb group protein EZH2 is involved in progression of prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
retrieved
7 July 2018
Role of histone H3 lysine 27 methylation in Polycomb-group silencing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237267
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7 July 2018
Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDDIS.2014.454
retrieved
21 January 2018
Identifiers
DOI
10.1038/CDDIS.2014.454
1 reference
stated in
Europe PubMed Central
PMC publication ID
4237267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25341040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
PMC publication ID
4237267
1 reference
stated in
Europe PubMed Central
PMC publication ID
4237267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25341040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
PubMed publication ID
25341040
1 reference
stated in
Europe PubMed Central
PMC publication ID
4237267
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25341040%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 February 2020
ResearchGate publication ID
267328913
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