(Q34542559)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

0 references

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Rainer Heuchel

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Hui Y Lan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Guan-Xian Liu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

You-Qi Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Xiao R Huang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Lihua Wei

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Yong-Jun Shi

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

language of work or name

English

0 references

publication date

3 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

e53573

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

21 February 2020

copyright license

start time

3 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Diverse roles of TGF-β/Smads in renal fibrosis and inflammation

1 reference

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TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29

7 July 2018

1 reference

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New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II

7 July 2018

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Cross-talk between miR-29 and transforming growth factor-betas in trabecular meshwork cells

7 July 2018

1 reference

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Epidemiology of hypertensive kidney disease

7 July 2018

1 reference

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The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential

7 July 2018

1 reference

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Angiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse model

7 July 2018

1 reference

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Hypertensive nephropathy: prevention and treatment recommendations

7 July 2018

1 reference

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Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

7 July 2018

1 reference

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Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition.

7 July 2018

1 reference

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Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia

7 July 2018

1 reference

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Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3

7 July 2018

1 reference

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NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma

7 July 2018

1 reference

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Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

7 July 2018

1 reference

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Smad7 as a therapeutic agent for chronic kidney diseases.

7 July 2018

1 reference

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Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity, and functional implication

7 July 2018

1 reference

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Latent TGF-beta1 protects against crescentic glomerulonephritis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

Specificity protein 1 and Smad-dependent regulation of human heme oxygenase-1 gene by transforming growth factor-beta1 in renal epithelial cells

7 July 2018

1 reference

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Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis

7 July 2018

1 reference

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Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway

7 July 2018

1 reference

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Deletion of exon I of SMAD7 in mice results in altered B cell responses.

7 July 2018

1 reference

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Essential role of Smad3 in angiotensin II-induced vascular fibrosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases

7 July 2018

1 reference

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Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7.

7 July 2018

1 reference

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Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.

7 July 2018

1 reference

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Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice

7 July 2018

1 reference

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The transcription factors Sp1 and Sp3 are required for human angiotensin II type 1 receptor gene expression in H295-R cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes

7 July 2018

1 reference

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Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.

7 July 2018

1 reference

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Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

7 July 2018

1 reference

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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

7 July 2018

1 reference

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Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

Sp1-like activity mediates angiotensin-II-induced plasminogen-activator inhibitor type-1 (PAI-1) gene expression in mesangial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3536757

Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053573

Smad3 mediates ANG II-induced hypertensive kidney disease in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053573

Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053573

Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053573

Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053573

Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053573

Suppression of type I collagen expression by miR-29b via PI3K, Akt, and Sp1 pathway in human Tenon's fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053573

Smad3 mediates cardiac inflammation and fibrosis in angiotensin II-induced hypertensive cardiac remodeling

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23301086

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23301086

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23301086

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0053573

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23301086%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

PubMed publication ID

23301086

1 reference