Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34543666)
Watch
English
Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-kappaB.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
title
Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-kappaB
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
main subject
sulfasalazine
1 reference
based on heuristic
inferred from title
brain tumor
1 reference
based on heuristic
inferred from title
author
Harald Sontheimer
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
author name string
W Joon Chung
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
language of work or name
English
0 references
publication date
29 April 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
number of pages
12
1 reference
based on heuristic
inferred from page(s)
published in
Journal of Neurochemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
volume
110
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
page(s)
182-193
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3031868/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
The xc- cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
A role for glutamate in growth and invasion of primary brain tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Shared principles in NF-kappaB signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
The x(c)- cystine/glutamate antiporter: a potential target for therapy of cancer and other diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Autocrine glutamate signaling promotes glioma cell invasion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Sulfasalazine-induced cystine starvation: potential use for prostate cancer therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Nuclear factor-kappaB in cancer development and progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Stimulus specificity of gene expression programs determined by temporal control of IKK activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Inhibition of cystine uptake disrupts the growth of primary brain tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
The role of glutathione in cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
In vitro and in vivo activity of the nuclear factor-kappaB inhibitor sulfasalazine in human glioblastomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Glutathione metabolism and its implications for health
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Malignant gliomas: perverting glutamate and ion homeostasis for selective advantage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
The role of NF-kappaB in the regulation of cell stress responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
NF-kappaB regulation in the immune system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Aberrant nuclear factor-kappaB activity and its participation in the growth of human malignant astrocytoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system xc-
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Human cystine/glutamate transporter: cDNA cloning and upregulation by oxidative stress in glioma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Glutamate uptake
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Inhibition of nuclear factor kappa B and induction of apoptosis in T-lymphocytes by sulfasalazine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Glioma cells release excitotoxic concentrations of glutamate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Inhibition of interleukin-1-stimulated NF-kappaB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
New insights into the role of nuclear factor-KB, a ubiquitous transcription factor in the initiation of diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Use of chlorotoxin for targeting of primary brain tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Sulfasalazine: a potent and specific inhibitor of nuclear factor kappa B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Letter: Neurotoxic effects of glutamate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Glutamate neurotoxicity and diseases of the nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
Pharmacological and biochemical actions of sulphasalazine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
7 July 2018
The Mayo Clinic-Canadian Cooperative trial of sulfasalazine in active multiple sclerosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1111%2FJ.1471-4159.2009.06129.X
retrieved
21 January 2018
NF-kappaB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
Characterization of oligodendrogliomas using short echo time 1H MR spectroscopic imaging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
[The frequency of seizures in patients with primary brain tumors or cerebral metastases. An evaluation from the Ludwig Boltzmann Institute of Neuro-Oncology and the Department of Neurology, Kaiser Franz Josef Hospital, Vienna].
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
Glutamate release promotes growth of malignant gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral microdialysis study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3031868
retrieved
27 October 2018
Identifiers
DOI
10.1111/J.1471-4159.2009.06129.X
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
PMC publication ID
3031868
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
PubMed publication ID
19457125
1 reference
stated in
Europe PubMed Central
PMC publication ID
3031868
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19457125%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 January 2020
ResearchGate publication ID
24441360
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
