(Q38355236)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12716947%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12716947%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress (English)

1 reference

10.1523/JNEUROSCI.23-08-03394.2003

Crossref

DOI

https://api.crossref.org/works/10.1523/JNEUROSCI.23-08-03394.2003

28 December 2023

1 reference

1 reference

Gloria Wong

3

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3 November 2019

Lei Jiang

5

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3 November 2019

Heidi Erb

6

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3 November 2019

Andy Y. Shih

1

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28 December 2023

Delinda A. Johnson

2

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28 December 2023

Andrew D. Kraft

4

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28 December 2023

Jeffrey A. Johnson

7

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28 December 2023

Timothy H. Murphy

8

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28 December 2023

language of work or name

English

0 references

publication date

1 April 2003

1 reference

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3 November 2019

15 April 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12716947

full work available at URL

28 December 2023

https://europepmc.org/articles/pmc6742304?pdf=render

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12716947

http://www.jneurosci.org/cgi/content/abstract/23/8/3394

28 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12716947

https://europepmc.org/articles/PMC6742304

28 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12716947

https://europepmc.org/articles/PMC6742304?pdf=render

28 December 2023

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12716947

https://doi.org/10.1523/jneurosci.23-08-03394.2003

28 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12716947

https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.23-08-03394.2003

28 December 2023

1 reference

10.1523/JNEUROSCI.23-08-03394.2003

Crossref

DOI

https://api.crossref.org/works/10.1523/JNEUROSCI.23-08-03394.2003

28 December 2023

published in

Journal of Neuroscience

1 reference

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3 November 2019

volume

23

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3 November 2019

issue

8

1 reference

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3 November 2019

page(s)

3394-3406

1 reference

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Activation of antioxidant/electrophile-responsive elements in IMR-32 human neuroblastoma cells

3 November 2019

cites work

1 reference

12 December 2020

Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

1 reference

12 December 2020

GSH transport in immortalized mouse brain endothelial cells: evidence for apical localization of a sodium-dependent GSH transporter

1 reference

12 December 2020

Evidence of glutathione transporter in rat brain synaptosomal membrane vesicles

1 reference

12 December 2020

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

1 reference

12 December 2020

Changes in amino acid concentrations over time and space around an impact injury and their diffusion through the rat spinal cord

1 reference

12 December 2020

Regulatory mechanisms of cellular response to oxidative stress

1 reference

12 December 2020

Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species

1 reference

12 December 2020

Nrf2 is essential for protection against acute pulmonary injury in mice

1 reference

12 December 2020

GSH transport in human cerebrovascular endothelial cells and human astrocytes: evidence for luminal localization of Na+-dependent GSH transport in HCEC.

1 reference

12 December 2020

Astrocytes provide cysteine to neurons by releasing glutathione

1 reference

12 December 2020

Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by MafK.

1 reference

12 December 2020

Evaluation of glutathione-sensitive fluorescent dyes in cortical culture.

1 reference

12 December 2020

The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin

1 reference

12 December 2020

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

1 reference

12 December 2020

Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

1 reference

12 December 2020

Thioredoxin reductase and glutathione synthesis is upregulated by t-butylhydroquinone in cortical astrocytes but not in cortical neurons

1 reference

12 December 2020

Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells

1 reference

12 December 2020

The multidrug resistance protein MRP1 mediates the release of glutathione disulfide from rat astrocytes during oxidative stress

1 reference

12 December 2020

Preferential expression of antioxidant response element mediated gene expression in astrocytes

1 reference

12 December 2020

xCt cystine transporter expression in HEK293 cells: pharmacology and localization

1 reference

12 December 2020

Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism

1 reference

12 December 2020

Oxidative glutamate toxicity can be a component of the excitotoxicity cascade.

1 reference

12 December 2020

Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells

1 reference

12 December 2020

c-Jun mediates axotomy-induced dopamine neuron death in vivo

1 reference

12 December 2020

Pathways of neuron-astrocyte interactions and their possible role in neuroprotection.

1 reference

12 December 2020

Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons

1 reference

12 December 2020

Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane

1 reference

12 December 2020

Role of NRF2 in protection against hyperoxic lung injury in mice

1 reference

12 December 2020

Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene

1 reference

12 December 2020

Activation of the mouse heme oxygenase-1 gene by 15-deoxy-Delta(12,14)-prostaglandin J(2) is mediated by the stress response elements and transcription factor Nrf2.

1 reference

12 December 2020

Time-dependent changes in ARE-driven gene expression by use of a noise-filtering process for microarray data

1 reference

12 December 2020

Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice

1 reference

12 December 2020

Glutathione release from cultured brain cells: multidrug resistance protein 1 mediates the release of GSH from rat astroglial cells

1 reference

12 December 2020

Drug targeting. Breaking down barriers

1 reference

12 December 2020

Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways.

1 reference

12 December 2020

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

1 reference

12 December 2020

Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression

1 reference

12 December 2020

Nrf2 degradation by the ubiquitin proteasome pathway is inhibited by KIAA0132, the human homolog to INrf2

1 reference

12 December 2020

Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

1 reference

12 December 2020

Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome

1 reference

12 December 2020

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

1 reference

12 December 2020

Glutathione turnover in cultured astrocytes: studies with [15N]glutamate

1 reference

12 December 2020

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

1 reference

12 December 2020

Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake

1 reference

12 December 2020

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1 reference

12 December 2020

Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

1 reference

12 December 2020

Exchange of cystine and glutamate across plasma membrane of human fibroblasts

1 reference

12 December 2020

Calcium-dependent and -independent release of glutamate from synaptosomes monitored by continuous fluorometry

1 reference

12 December 2020

Alteration of amino acid content of cerebrospinal fluid from patients with epilepsy

1 reference

12 December 2020

Staurosporine, a potent inhibitor of phospholipid/Ca++dependent protein kinase

1 reference

12 December 2020

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

12 December 2020

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

1 reference

12 December 2020

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

12 December 2020

Differential expression of heme oxygenase-1 in cultured cortical neurons and astrocytes determined by the aid of a new heme oxygenase antibody. Response to oxidative stress

1 reference

12 December 2020

A detailed analysis of hydrogen peroxide-induced cell death in primary neuronal culture

1 reference

12 December 2020

Cystine uptake and glutathione level in fetal brain cells in primary culture and in suspension

1 reference

12 December 2020

Oxidative stress, glutamate, and neurodegenerative disorders

1 reference

12 December 2020

Oxidative stress induces apoptosis in embryonic cortical neurons.

1 reference

12 December 2020

Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain

1 reference

12 December 2020

Glia: the brain's other cells

1 reference

12 December 2020

Maintenance of neuronal glutathione by glial cells

1 reference

12 December 2020

The electrophile counterattack response: protection against neoplasia and toxicity.

1 reference

12 December 2020

Evidence for the existence of a sodium-dependent glutathione (GSH) transporter. Expression of bovine brain capillary mRNA and size fractions in Xenopus laevis oocytes and dissociation from gamma-glutamyltranspeptidase and facilitative GSH transporte

1 reference

12 December 2020

Glia conditioned medium protects fetal rat midbrain neurones in culture from L-DOPA toxicity.

1 reference

12 December 2020

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

1 reference

12 December 2020

Glutathione efflux from cultured astrocytes

1 reference

12 December 2020

Astrocytes protect neurons from hydrogen peroxide toxicity

1 reference

12 December 2020

Antioxidant-inducible genes

1 reference

12 December 2020

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

1 reference

12 December 2020

Different preferences in the utilization of amino acids for glutathione synthesis in cultured neurons and astroglial cells derived from rat brain.

1 reference

12 December 2020

Postnatal retinal ganglion cells in vitro: protection against reactive oxygen species (ROS)-induced axonal degeneration by cocultured astrocytes.

1 reference

12 December 2020

Construction of adenovirus vectors through Cre-lox recombination

1 reference

12 December 2020

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

12 December 2020

Chemoprevention by inducers of carcinogen detoxication enzymes

1 reference

12 December 2020

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

1 reference

12 December 2020

Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency.

1 reference

12 December 2020

1 reference

12 December 2020

Histochemical detection of quinone reductase activity in situ using LY 83583 reduction and oxidation.

1 reference

12 December 2020

The regulation of reactive oxygen species production during programmed cell death

1 reference

12 December 2020

Activation of endogenous antioxidant defenses in neuronal cells prevents free radical-mediated damage.

1 reference

12 December 2020

Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

1 reference

12 December 2020

Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione

1 reference

12 December 2020

Coordinate regulation of NAD(P)H:quinone oxidoreductase and glutathione-S-transferases in primary cultures of rat neurons and glia: role of the antioxidant/electrophile responsive element

1 reference

12 December 2020

10.1523/JNEUROSCI.23-08-03394.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12716947%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12716947%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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