(Q34543726)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

Functional significance of erythropoietin in renal cell carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

20 November 2019

1 reference

29 May 2020

1 reference

20 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

David Johnson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

David A Vesey

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Glenda C Gobe

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

10 January 2013

4 references

3 April 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

29 May 2020

4 references

3 April 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

29 May 2020

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 2.0 Generic

22 February 2020

copyright license

2 references

3 April 2019

on focus list of Wikimedia project

20 November 2019

copyright status

copyrighted

0 references

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2407-13-14

0 references

cites work

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7 July 2018

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7 July 2018

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Recombinant human erythropoietin promotes the acquisition of a malignant phenotype in head and neck squamous cell carcinoma cell lines in vitro

7 July 2018

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7 July 2018

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7 July 2018

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The PI3K/Akt/mTOR pathway mediates retinal progenitor cell survival under hypoxic and superoxide stress

7 July 2018

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7 July 2018

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7 July 2018

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VHL and HIF signalling in renal cell carcinogenesis

7 July 2018

1 reference

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The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy

7 July 2018

1 reference

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Erythroid-stimulating agents in cancer therapy: potential dangers and biologic mechanisms

7 July 2018

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Association of abnormal preoperative laboratory values with survival after radical nephrectomy for clinically confined clear cell renal cell carcinoma.

7 July 2018

1 reference

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Erythropoietin reduces cisplatin-induced apoptosis in renal carcinoma cells via a PKC dependent pathway.

7 July 2018

1 reference

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Does inhibition of degradation of hypoxia-inducible factor (HIF) alpha always lead to activation of HIF? Lessons learnt from the effect of proteasomal inhibition on HIF activity

7 July 2018

1 reference

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Erythropoietin gene expression in renal carcinoma is considerably more frequent than paraneoplastic polycythemia

7 July 2018

1 reference

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Ubiquitin pathway in VHL cancer syndrome

7 July 2018

1 reference

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The von Hippel-Lindau tumor suppressor protein: roles in cancer and oxygen sensing

7 July 2018

1 reference

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Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor

7 July 2018

1 reference

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2004 WHO classification of the renal tumors of the adults

7 July 2018

1 reference

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Role of VHL gene mutation in human cancer

7 July 2018

1 reference

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The erythropoietin receptor and its expression in tumor cells and other tissues

7 July 2018

1 reference

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Chemosensitization by erythropoietin through inhibition of the NF-kappaB rescue pathway

7 July 2018

1 reference

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Von Hippel-Lindau tumor suppressor protein and hypoxia-inducible factor in kidney cancer

7 July 2018

1 reference

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7 July 2018

VHL and Kidney Cancer

1 reference

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Hypoxia-inducible factor and its biomedical relevance

7 July 2018

1 reference

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Clinical review 155: Pheochromocytoma in Von Hippel-Lindau disease

7 July 2018

1 reference

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Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex

7 July 2018

1 reference

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Receptor dimerization in GH and erythropoietin action--it takes two to tango, but how?

7 July 2018

1 reference

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A phase II study of subcutaneous low-dose interleukin-2 plus erythropoietin in metastatic renal cell carcinoma progressing on interleukin-2 alone

7 July 2018

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

7 July 2018

1 reference

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Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

7 July 2018

1 reference

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Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

7 July 2018

1 reference

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Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

7 July 2018

1 reference

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Signal transduction in the erythropoietin receptor system

7 July 2018

1 reference

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Protein kinase B (c-Akt), phosphatidylinositol 3-kinase, and STAT5 are activated by erythropoietin (EPO) in HCD57 erythroid cells but are constitutively active in an EPO-independent, apoptosis-resistant subclone (HCD57-SREI cells).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

The molecular biology of erythropoietin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Erythropoietin production by interstitial cells of hypoxic monkey kidneys

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Erythropoietin production in liver and kidneys.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Studies on the liver to kidney switch of erythropoietin production

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

New human renal carcinoma cell line established from a patient with erythrocytosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Production of erythropoietin-like activity by human renal and hepatic carcinomas in cell culture.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Continuous production of erythropoietin by an established human renal carcinoma cell line: development of the cell line

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Peritubular cells are the site of erythropoietin synthesis in the murine hypoxic kidney

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Tumor cells are the site of erythropoietin synthesis in human renal cancers associated with polycythemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Erythropoietin: sites of synthesis and regulation of secretion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Studies on the role of recombinant human erythropoietin in the growth regulation of human nonhematopoietic tumor cells in vitro.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Erythropoietin in renal cell carcinoma: evaluation of its usefulness as a tumor marker.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Erythropoietin production by human renal carcinoma cells in culture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Erythropoietin levels in the course of a patient with erythropoietin-producing renal cell carcinoma and transplantation of this tumor in nude mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Coexpression of erythopoietin and erythopoietin receptor in sporadic clear cell renal cell carcinoma.

7 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-13-14

Novel somatic mutations of the VHL gene in an erythropoietin-producing renal carcinoma associated with secondary polycythemia and elevated circulating endothelial progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-13-14

Paraneoplastic erythrocytosis associated with an inactivating point mutation of the von Hippel-Lindau gene in a renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-13-14

Prognostic significance of erythropoietin expression in human renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-13-14

Prevalence of paraneoplastic erythropoietin production by renal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-13-14

Expression of erythropoietin and its receptor in human renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-13-14

Tumor-derived tumor necrosis factor-alpha promotes progression and epithelial-mesenchymal transition in renal cell carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-13-14

Coexpression of erythropoietin and erythropoietin receptor in von Hippel-Lindau disease-associated renal cysts and renal cell carcinoma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Erythropoietin production in a primary culture of human renal carcinoma cells maintained in nude mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554558

Breast cancer trial with erythropoietin terminated unexpectedly

27 October 2018

1 reference

12 December 2020

Erythropoietin levels in patients with renal tumors or cysts

1 reference

12 December 2020

Erythropoietin-producing renal cell carcinoma arising from acquired cystic disease of the kidney

1 reference

12 December 2020

Erythropoietin production in human renal carcinoma cells passaged in nude mice and in tissue culture

1 reference

12 December 2020

Pure erythropoiesis in clear cell renal cell carcinoma

1 reference

12 December 2020

Erythropoietin-induced secondary polycythemia in a patient with a renal cell carcinoma. A case report

1 reference

12 December 2020

[Treatment of advanced kidney cancer using recombinant erythropoietin]

1 reference

12 December 2020

Gene expression of erythropoietin in renal cell carcinoma

1 reference

12 December 2020

VHL alterations in human clear cell renal cell carcinoma: association with advanced tumor stage and a novel hot spot mutation

1 reference

12 December 2020

Erythropoietin stimulates proliferation of human renal carcinoma cells

1 reference

12 December 2020

Clinical significance of erythropoietin levels in renal carcinoma

1 reference

12 December 2020

Erythropoietin production. A potential marker for interleukin-2/interferon-responsive tumors

1 reference

12 December 2020

Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization

1 reference

12 December 2020

Comprehensive mutational analysis of the VHL gene in sporadic renal cell carcinoma: relationship to clinicopathological parameters

1 reference

12 December 2020

Production of erythropoietin by an established human renal carcinoma cell line: in vitro and in vivo studies

1 reference

12 December 2020

The erythropoietin receptor

1 reference

12 December 2020

Higher susceptibility of erythropoietin-producing renal cell carcinomas to lysis by lymphokine-activated killer cells

1 reference

12 December 2020

Erythropoietin, tumours and the von Hippel-Lindau gene: towards identification of mechanisms and dysfunction of oxygen sensing

1 reference

12 December 2020

Renal cell carcinoma and erythropoietin

1 reference

12 December 2020

Renal Cell Carcinoma With Erythrocytosis and Elevated Erythropoietic Stimulatory Activity

1 reference

12 December 2020

Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial

1 reference

12 December 2020

Erythropoietin release from renal cell carcinomas grown in tissue culture

1 reference

12 December 2020

Erythropoietin immunolocalization in renal cell carcinoma

1 reference

12 December 2020

Expression of renal cell carcinoma-associated markers erythropoietin, CD10, and renal cell carcinoma marker in diffuse malignant mesothelioma and metastatic renal cell carcinoma

1 reference

12 December 2020

Metastatic renal cell carcinoma: response to treatment with human recombinant erythropoietin

1 reference

12 December 2020

The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-13-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23305401%20AND%20SRC:MED&resulttype=core&format=json