(Q34544332)

2 August 2017

title

Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization (English)

1 reference

2 August 2017

author

Michel C. Nussenzweig

series ordinal

3

object named as

Michel C Nussenzweig

1 reference

2 August 2017

1

Anna Gazumyan

1 reference

2 August 2017

2

Amy Reichlin

1 reference

2 August 2017

language of work or name

English

0 references

publication date

3 July 2006

1 reference

Journal of Experimental Medicine

2 August 2017

published in

1 reference

2 August 2017

volume

203

1 reference

2 August 2017

issue

7

1 reference

2 August 2017

page(s)

1785-1794

1 reference

Plasticity of B cell receptor internalization upon conditional depletion of clathrin

2 August 2017

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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B cell development is arrested at the immature B cell stage in mice carrying a mutation in the cytoplasmic domain of immunoglobulin beta

7 July 2018

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7 July 2018

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7 July 2018

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The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction

7 July 2018

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CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A pathway for regulation of B lymphocyte antigen receptor-induced calcium flux

7 July 2018

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7 July 2018

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Genetic analysis of B cell antigen receptor signaling

7 July 2018

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Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels

7 July 2018

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Role of the inositol phosphatase SHIP in B cell receptor-induced Ca2+ oscillatory response.

7 July 2018

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SHIP modulates immune receptor responses by regulating membrane association of Btk.

7 July 2018

1 reference

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Inhibition of the B cell by CD22: a requirement for Lyn

7 July 2018

1 reference

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A tyrosine-based signal present in Ig alpha mediates B cell receptor constitutive internalization.

7 July 2018

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Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

7 July 2018

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Deletion of SHIP or SHP-1 reveals two distinct pathways for inhibitory signaling

7 July 2018

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The immunoglobulin (Ig)alpha and Igbeta cytoplasmic domains are independently sufficient to signal B cell maturation and activation in transgenic mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Initiation and processing of signals from the B cell antigen receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Endosomal targeting by the cytoplasmic tail of membrane immunoglobulin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Endocytosis and molecular sorting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Regulation of ITAM signaling by specific sequences in Ig-beta B cell antigen receptor subunit.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Clonal selection and learning in the antibody system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Tyrosine-phosphorylated forms of Ig beta, CD22, TCR zeta and HOSS are major ligands for tandem SH2 domains of Syk

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

CD22 associates with the human surface IgM-B-cell antigen receptor complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Antigen presentation by the B cell antigen receptor is driven by the alpha/beta sheath and occurs independently of its cytoplasmic tyrosines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

The alpha/beta sheath and its cytoplasmic tyrosines are required for signaling by the B-cell antigen receptor but not for capping or for serine/threonine-kinase recruitment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Ig alpha and Ig beta are functionally homologous to the signaling proteins of the T-cell receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Internalization of B cell and pre-B cell receptors is regulated by tyrosine kinase and phosphatase activities.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Role of B cell receptor Ig alpha and Ig beta subunits in MHC class II-restricted antigen presentation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Interactions of Lyn with the antigen receptor during B cell activation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Syk tyrosine kinase required for mouse viability and B-cell development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

B29: a member of the immunoglobulin gene superfamily exclusively expressed on beta-lineage cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Peritoneal Ly-1 B cells: genetic control, autoantibody production, increased lambda light chain expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Antigen receptor tail clue.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Structure and function of the complement receptors, CR1 (CD35) and CR2 (CD21).

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

7 July 2018

https://api.crossref.org/works/10.1084%2FJEM.20060221

B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Molecular components of the B-cell antigen receptor complex of the IgM class.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Mutations of immunoglobulin transmembrane and cytoplasmic domains: effects on intracellular signaling and antigen presentation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Functional reconstitution of an immunoglobulin antigen receptor in T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Tyrosine phosphorylation is required for ligand-induced internalization of the antigen receptor on B lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer

7 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

Differential regulation of the B cell receptor-mediated signaling by the E3 ubiquitin ligase Cbl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

Ig alpha and Ig beta are required for efficient trafficking to late endosomes and to enhance antigen presentation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118343

Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR Complex

27 October 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

Ig-α Cytoplasmic Truncation Renders Immature B Cells More Sensitive to Antigen Contact

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20060221

A negative regulatory role for Ig-alpha during B cell development

21 January 2018

1 reference

12 December 2020

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

1 reference

12 December 2020

Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice

1 reference

12 December 2020

Tyrosine Phosphorylation of CD22 During B Cell Activation

1 reference

12 December 2020

Asymmetrical phosphorylation and function of immunoreceptor tyrosine-based activation motif tyrosines in B cell antigen receptor signal transduction

1 reference

12 December 2020

Differential signaling through the Ig-alpha and Ig-beta components of the B cell antigen receptor

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20060221

1 reference

2 August 2017

1 reference

2 August 2017

1 reference