(Q34544824)

2 August 2017

title

Low CSF levels of both α-synuclein and the α-synuclein cleaving enzyme neurosin in patients with synucleinopathy (English)

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2 August 2017

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7

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2 August 2017

5

Lennart Minthon

1 reference

2 August 2017

Malin Wennström

1

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2 August 2017

Yulia Surova

2

1 reference

2 August 2017

Sara Hall

3

1 reference

2 August 2017

Christer Nilsson

4

1 reference

2 August 2017

Fredrik Boström

6

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2 August 2017

Henrietta M Nielsen

8

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2 August 2017

language of work or name

English

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publication date

8 January 2013

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2 August 2017

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2 August 2017

volume

8

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2 August 2017

issue

1

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2 August 2017

page(s)

e53250

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

8 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Lentivirus mediated delivery of neurosin promotes clearance of wild-type α-synuclein and reduces the pathology in an α-synuclein model of LBD.

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7 July 2018

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Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

7 July 2018

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Controlling the mass action of alpha-synuclein in Parkinson's disease

7 July 2018

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Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration

7 July 2018

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Value of measuring plasmatic levels of neurosin in the diagnosis of Alzheimer's disease

7 July 2018

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Cloning and characterization of novel isoforms of the human kallikrein 6 gene

7 July 2018

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Characterization of the enzymatic activity of human kallikrein 6: Autoactivation, substrate specificity, and regulation by inhibitors

7 July 2018

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Staging of brain pathology related to sporadic Parkinson's disease

7 July 2018

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Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease

7 July 2018

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The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy.

7 July 2018

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alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain

7 July 2018

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7 July 2018

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7 July 2018

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Alpha-synuclein immunoreactivity in glial cytoplasmic inclusions in multiple system atrophy

7 July 2018

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Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy.

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Multiple-system atrophy: a new alpha-synuclein disease?

21 January 2018

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Differential levels of alpha-synuclein, beta-amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Decreased alpha-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Extracellular neurosin degrades α-synuclein in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Cleavage of normal and pathological forms of alpha-synuclein by neurosin in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Substrate specificity of human kallikrein 6: salt and glycosaminoglycan activation effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Characterization of a brain-related serine protease, neurosin (human kaillikrein 6), in human cerebrospinal fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Human kallikrein 6 as a biomarker of alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Cerebrospinal fluid alpha-synuclein in neurodegenerative disorders-a marker of synapse loss?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Altered CSF orexin and α-synuclein levels in dementia patients.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540093

CSF α-synuclein does not discriminate dementia with Lewy bodies from Alzheimer's disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540093

Cerebrospinal fluid alpha-synuclein does not discriminate between dementia disorders.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540093

Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3540093

Dementia with Lewy bodies

27 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Cerebrospinal fluid Tau/α-synuclein ratio in Parkinson's disease and degenerative dementias

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Immunofluorometric assay of human kallikrein 6 (zyme/protease M/neurosin) and preliminary clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0053250

Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23308173

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Alpha-synuclein in the cerebrospinal fluid differentiates synucleinopathies (Parkinson Disease, dementia with Lewy bodies, multiple system atrophy) from Alzheimer disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23308173

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0053250

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference