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XIAP impairs Smac release from the mitochondria during apoptosis.
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
title
XIAP impairs Smac release from the mitochondria during apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
main subject
mitochondrion
1 reference
based on heuristic
inferred from title
apoptotic process
1 reference
based on heuristic
inferred from title
author
Lorna Flanagan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
Marc C Devocelle
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
Jochen Prehn
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7
1 reference
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
Markus Rehm
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8
1 reference
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
author name string
J Sebastià
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
L P Tuffy
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
A Spring
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4
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
A Lichawska
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5
1 reference
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
publication date
3 June 2010
1 reference
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
published in
Cell Death and Disease
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stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
volume
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
page(s)
e49
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Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3032314/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
XIAP mediates NOD signaling via interaction with RIP2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Proteomics of mitochondrial inner and outer membranes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Intracellular signaling dynamics during apoptosis execution in the presence or absence of X-linked-inhibitor-of-apoptosis-protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Quantitative analysis of pathways controlling extrinsic apoptosis in single cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Systems analysis of effector caspase activation and its control by X-linked inhibitor of apoptosis protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Disturbed balance of expression between XIAP and Smac/DIABLO during tumour progression in renal cell carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Dual role of BRUCE as an antiapoptotic IAP and a chimeric E2/E3 ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
An improved cyan fluorescent protein variant useful for FRET
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
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7 July 2018
Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Real-time single cell analysis of Smac/DIABLO release during apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Mechanism of XIAP-mediated inhibition of caspase-9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
X-linked inhibitor of apoptosis protein functions as a cofactor in transforming growth factor-beta signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Structural Basis of Caspase Inhibition by XIAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Structural basis of IAP recognition by Smac/DIABLO
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
7 July 2018
Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDDIS.2010.26
retrieved
21 January 2018
Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDDIS.2010.26
retrieved
21 January 2018
Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FCDDIS.2010.26
retrieved
21 January 2018
Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
27 October 2018
Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3032314
retrieved
27 October 2018
xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21364655
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21364655
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/CDDIS.2010.26
1 reference
stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
PMC publication ID
3032314
1 reference
stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
PubMed publication ID
21364655
1 reference
stated in
Europe PubMed Central
PMC publication ID
3032314
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21364655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
24 January 2020
ResearchGate publication ID
50250573
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