(Q34548314)

2 August 2017

1 reference

title

Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases (English)

1 reference

2 August 2017

Adam P Curnock

1

1 reference

PubMed ID

11872087

2 August 2017

Marisa K Logan

series ordinal

2

1 reference

PubMed ID

11872087

2 August 2017

Stephen G Ward

series ordinal

3

1 reference

2 August 2017

1 February 2002

1 reference

2 August 2017

1 reference

2 August 2017

105

1 reference

2 August 2017

125-136

1 reference

2 August 2017

2

1 reference

Chemokines: a new classification system and their role in immunity

2 August 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Chemokines: understanding their role in T-lymphocyte biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Chemokines and T lymphocytes: more than an attraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Leukocyte polarization in cell migration and immune interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Selective G protein coupling by C-C chemokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Distinct PI(3)Ks mediate mitogenic signalling and cell migration in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Role of phosphoinositide 3-kinase in monocyte recruitment under flow conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Autophosphorylation of p110δ phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Rho family GTPases bind to phosphoinositide kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

A novel role for phosphatidylinositol 3-kinase beta in signaling from G protein-coupled receptors to Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Protein kinase cascades activated by stress and inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Interleukin-8 receptors R1 and R2 activate mitogen-activated protein kinases and induce c-fos, independent of Ras and Raf-1 in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Evidence of zeta protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Regulating integrin-mediated adhesion: one more function for PI 3-kinase?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

Activation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human mo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01345.X

T-Cell Function and Migration — Two Sides of the Same Coin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Src tyrosine kinase is a novel direct effector of G proteins.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

MIP-3alpha induces human eosinophil migration and activation of the mitogen-activated protein kinases (p42/p44 MAPK).

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Chemokine-induced monocyte transmigration requires cdc42-mediated cytoskeletal changes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Identification and characterization of the CXCR4 chemokine receptor in human T cell lines: ligand binding, biological activity, and HIV-1 infectivity

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

G protein-coupled signal transduction pathways for interleukin-8

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Gi-mediated activation of the p21ras-mitogen-activated protein kinase pathway by alpha 2-adrenergic receptors expressed in fibroblasts

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

RANTES-activated human T lymphocytes. A role for phosphoinositide 3-kinase

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

C-C chemokines induce the chemotaxis of NK and IL-2-activated NK cells. Role for G proteins.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

Receptor-activated calcium influx in human monocytes exposed to monocyte chemotactic protein-1 and related cytokines

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1782650

G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

27 October 2018

1 reference

12 December 2020

MAP kinase function in amoeboid chemotaxis

1 reference

12 December 2020

Phosphoinositide 3-kinase gamma is a mediator of Gbetagamma-dependent Jun kinase activation

1 reference

12 December 2020

Importance of MEK in neutrophil microbicidal responsiveness

1 reference

12 December 2020

Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

1 reference

12 December 2020

Activation of mitogen-activated protein kinase regulates eotaxin-induced eosinophil migration

1 reference

12 December 2020

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

12 December 2020

PI 3-kinase-dependent and independent chemotaxis of human neutrophil leukocytes

1 reference

12 December 2020

Phosphoinositide 3-kinase gamma and p85/phosphoinositide 3-kinase in platelets. Relative activation by thrombin receptor or beta-phorbol myristate acetate and roles in promoting the ligand-binding function of alphaIIbbeta3 integrin

1 reference

12 December 2020

Activation of dual T cell signaling pathways by the chemokine RANTES

1 reference

12 December 2020

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

1 reference

12 December 2020

10.1046/J.1365-2567.2002.01345.X

Identifiers

DOI

1 reference

release_5ypbkdrzgvg7hp5nuqg6nqzhwm

2 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5ypbkdrzgvg7hp5nuqg6nqzhwm

24 November 2022

mapped directly with Wikidata item

0 references

1 reference

PubMed ID

11872087