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Hexosamines as mediators of nutrient sensing and regulation in diabetes.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
review article
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Europe PubMed Central
title
Hexosamines as mediators of nutrient sensing and regulation in diabetes
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author
Don A McClain
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
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7 December 2019
author name string
Donald A McClain
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1
1 reference
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Europe PubMed Central
PubMed publication ID
11872372
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2 August 2017
publication date
1 January 2002
1 reference
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Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Journal of Diabetes and its Complications
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
16
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
72-80
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.
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Glucosamine induces insulin resistance in vivo by affecting GLUT 4 translocation in skeletal muscle. Implications for glucose toxicity
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A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
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7 January 2021
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c-Myc Is Glycosylated at Threonine 58, a Known Phosphorylation Site and a Mutational Hot Spot in Lymphomas
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reference URL
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7 January 2021
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O-Glycosylation of nuclear and cytosolic proteins. Dynamic interplay between O-GlcNAc and O-phosphate
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7 January 2021
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Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione.
1 reference
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7 January 2021
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Glutamine:fructose-6-phosphate amidotransferase activity in cultured human skeletal muscle cells: relationship to glucose disposal rate in control and non-insulin-dependent diabetes mellitus subjects and regulation by glucose and insulin
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7 January 2021
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In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat: possible relevance to the maladaptive responses to chronic hyperglycaemia
1 reference
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Crossref
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7 January 2021
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Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility
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7 January 2021
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Glycosylation in the nucleus and cytoplasm
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the glucosamine pathway in fat-induced insulin resistance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
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Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance
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Crossref
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7 January 2021
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Obesity-independent hyperinsulinemia in nondiabetic first-degree relatives of individuals with type 2 diabetes.
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7 January 2021
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O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation
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7 January 2021
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SPINDLY, a tetratricopeptide repeat protein involved in gibberellin signal transduction in Arabidopsis
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7 January 2021
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Insights into insulin resistance and type 2 diabetes from knockout mouse models
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7 January 2021
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Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance
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7 January 2021
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Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteins
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7 January 2021
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Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.
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7 January 2021
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Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle.
1 reference
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Crossref
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7 January 2021
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Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
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inferred from DOI database lookup
Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Progressive decline in insulin levels in Rabson-Mendenhall syndrome.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hexosamines stimulate leptin production in transgenic mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of glucosamine infusion on insulin secretion and insulin action in humans.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo glucosamine infusion induces insulin resistance in normoglycemic but not in hyperglycemic conscious rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucosamine infusion in rats mimics the beta-cell dysfunction of non-insulin-dependent diabetes mellitus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase II
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human glucokinase gene: isolation, characterization, and identification of two missense mutations linked to early-onset non-insulin-dependent (type 2) diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin action and secretion in healthy, glucose tolerant first degree relatives of patients with type 2 diabetes mellitus. Influence of body weight
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A nutrient-sensing pathway regulates leptin gene expression in muscle and fat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UDP-N-acetylglucosamine transferase and glutamine: fructose 6-phosphate amidotransferase activities in insulin-sensitive tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of troglitazone and D-chiroinositol on glucosamine-induced insulin resistance in vivo in rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1056-8727%2801%2900188-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1056-8727(01)00188-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
PubMed publication ID
11872372
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11872372
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11872372%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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