(Q34551011)

English

Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Piotr J Mak

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Ilia G Denisov

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Yelena V Grinkova

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Stephen G Sligar

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

James R Kincaid

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

0 references

publication date

5 January 2011

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Journal of the American Chemical Society

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

133

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1357-1366

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Defining the structural consequences of mechanism-based inactivation of mammalian cytochrome P450 2B4 using resonance Raman spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

P450 enzymes: their structure, reactivity, and selectivity-modeled by QM/MM calculations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Mixing apples and oranges: Analysis of heterotropic cooperativity in cytochrome P450 3A4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Cooperative properties of cytochromes P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Resonance Raman spectroscopic studies of hydroperoxo derivatives of cobalt-substituted myoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Defining resonance Raman spectral responses to substrate binding by cytochrome P450 from Pseudomonas putida

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

The ferrous-oxy complex of human aromatase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

QM/MM study of the active species of the human cytochrome P450 3A4, and the influence thereof of the multiple substrate binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Redox potential control by drug binding to cytochrome P450 3A4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Resonance Raman detection of the hydroperoxo intermediate in the cytochrome P450 enzymatic cycle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Differential sensing of protein influences by NO and CO vibrations in heme adducts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

A malleable catalyst dominates the metabolism of drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Structural basis for ligand promiscuity in cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Current views on the fundamental mechanisms of cytochrome P450 allosterism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Structures of cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

CO as a vibrational probe of heme protein active sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Finding a single-molecule solution for membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Self‐assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Single-molecule height measurements on microsomal cytochrome P450 in nanometer-scale phospholipid bilayer disks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

The erythromycin breath test for the prediction of drug clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Cytochrome P-450 3A4: regulation and role in drug metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Mutagenic, electrochemical, and crystallographic investigation of the cytochrome b5 oxidation-reduction equilibrium: involvement of asparagine-57, serine-64, and heme propionate-7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

A method for preparing analytically pure sodium dithionite. Dithionite quality and observed nitrogenase-specific activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Substrate analogue induced changes of the CO-stretching mode in the cytochrome P450cam-carbon monoxide complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

7 July 2018

Resonance Raman studies of cytochrome P450 2B4 in its interactions with substrates and redox partners

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Ligand binding to cytochrome P450 3A4 in phospholipid bilayer nanodiscs: the effect of model membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Allosteric mechanisms in cytochrome P450 3A4 studied by high-pressure spectroscopy: pivotal role of substrate-induced changes in the accessibility and degree of hydration of the heme pocket.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Structural dynamics of the cooperative binding of organic molecules in the human cytochrome P450 3A4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Effects of systematic peripheral group deuteration on the low-frequency resonance Raman spectra of myoglobin derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Phe393 mutants of cytochrome P450 BM3 with modified heme redox potentials have altered heme vinyl and propionate conformations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Hydrogen-bonding interactions in the active sites of cytochrome P450cam and its site-directed mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Functional implications of the proximal hydrogen-bonding network in myoglobin: a resonance Raman and kinetic study of Leu89, Ser92, His97, and F-helix swap mutants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Oxidation of nonionic detergents by cytochrome P450 enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Analysis of four residues within substrate recognition site 4 of human cytochrome P450 3A4: role in steroid hydroxylase activity and alpha-naphthoflavone stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

Resonance Raman investigations of Escherichia coli-expressed Pseudomonas putida cytochrome P450 and P420

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

27 October 2018

The One-electron Autoxidation of Human Cytochrome P450 3A4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

9 December 2018

Cooperativity in Cytochrome P450 3A4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

9 December 2018

The Ferrous-Dioxygen Intermediate in Human Cytochrome P450 3A4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

9 December 2018

Resonance Raman Spectroscopic Studies of Hydroperoxo-Myoglobin at Cryogenic Temperatures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033474

9 December 2018

Low frequency resonance Raman spectra of isolated alpha and beta subunits of hemoglobin and their deuterated analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/21207936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allosteric P450 mechanisms: multiple binding sites, multiple conformers or both?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21207936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The resonance Raman frequencies of the Fe-CO stretching and bending modes in the CO complex of cytochrome P-450cam

1 reference

https://pubmed.ncbi.nlm.nih.gov/21207936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resonance Raman studies of cytochrome P450BM3 and its complexes with exogenous ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/21207936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Raman evidence for specific substrate-induced structural changes in the heme pocket of human cytochrome P450 aromatase during the three consecutive oxygen activation steps

1 reference

https://pubmed.ncbi.nlm.nih.gov/21207936

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA105869P

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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