(Q34555685)

English

Differential processing of let-7a precursors influences RRM2 expression and chemosensitivity in pancreatic cancer: role of LIN-28 and SET oncoprotein

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Differential processing of let-7a precursors influences RRM2 expression and chemosensitivity in pancreatic cancer: role of LIN-28 and SET oncoprotein (English)

1 reference

Europe PubMed Central

3 August 2017

pancreatic cancer

1 reference

based on heuristic

inferred from title

author name string

Yangzom Doma Bhutia

1

1 reference

Europe PubMed Central

3 August 2017

Sau Wai Hung

2

1 reference

Europe PubMed Central

3 August 2017

Madeline Krentz

3

1 reference

Europe PubMed Central

3 August 2017

Dimal Patel

4

1 reference

Europe PubMed Central

3 August 2017

Dylan Lovin

5

1 reference

Europe PubMed Central

3 August 2017

Radhika Manoharan

6

1 reference

Europe PubMed Central

3 August 2017

J Michael Thomson

7

1 reference

Europe PubMed Central

3 August 2017

Rajgopal Govindarajan

8

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

15 January 2013

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

8

1 reference

Europe PubMed Central

3 August 2017

1

1 reference

Europe PubMed Central

3 August 2017

e53436

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

15 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Overcoming nucleoside analog chemoresistance of pancreatic cancer: a therapeutic challenge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

MicroRNAs in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer

1 reference

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7 July 2018

Let-7 modulates acquired resistance of ovarian cancer to Taxanes via IMP-1-mediated stabilization of multidrug resistance 1

1 reference

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7 July 2018

Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice.

1 reference

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7 July 2018

Functional analysis of microRNAs in human hepatocellular cancer stem cells

1 reference

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7 July 2018

CNT1 expression influences proliferation and chemosensitivity in drug-resistant pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

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Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy

1 reference

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7 July 2018

LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Pancreatic cancer: understanding and overcoming chemoresistance

1 reference

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Targeting microRNAs in cancer: rationale, strategies and challenges

1 reference

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The potential functions of primary microRNAs in target recognition and repression

1 reference

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The translational regulator eIF3a: the tricky eIF3 subunit!

1 reference

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7 July 2018

Antagonistic role of hnRNP A1 and KSRP in the regulation of let-7a biogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

MicroRNA let-7: an emerging next-generation cancer therapeutic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Recent developments in palliative chemotherapy for locally advanced and metastatic pancreas cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Clinical pharmacology and pharmacogenetics of gemcitabine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

let-7 MicroRNA transfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

let-7 Overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34, and stabilization of Wee1 kinase in primary fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Expression of multidrug resistance-associated protein 2 is involved in chemotherapy resistance in human pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

The let-7 family of microRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

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Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

Switching from repression to activation: microRNAs can up-regulate translation

1 reference

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7 July 2018

The let-7 microRNA represses cell proliferation pathways in human cells

1 reference

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The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

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Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

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Extensive post-transcriptional regulation of microRNAs and its implications for cancer

1 reference

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Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells

1 reference

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MicroRNA expression profiles classify human cancers

1 reference

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RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance

1 reference

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1 reference

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7 July 2018

S Phase-specific transcription of the mouse ribonucleotide reductase R2 gene requires both a proximal repressive E2F-binding site and an upstream promoter activating region

1 reference

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7 July 2018

RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine

1 reference

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1 reference

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1 reference

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7 July 2018

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1 reference

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7 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

7 July 2018

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1 reference

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Ribonucleotide reductase subunit M2 mRNA expression in pretreatment biopsies obtained from unresectable pancreatic carcinomas

1 reference

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Analysis of ribonucleotide reductase M2 mRNA levels in patient samples after GTI-2040 antisense drug treatment.

1 reference

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Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

27 October 2018

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1 reference

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c-Myc initiates illegitimate replication of the ribonucleotide reductase R2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546076

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Lin28: A microRNA regulator with a macro role

1 reference

https://pubmed.ncbi.nlm.nih.gov/23335963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypermethylation of let-7a-3 in epithelial ovarian cancer is associated with low insulin-like growth factor-II expression and favorable prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23335963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0053436

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...853436B

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1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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