(Q34558567)

3 August 2017

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title

Immunosuppressive therapy for paediatric transplant patients: pharmacokinetic considerations (English)

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3 August 2017

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María del Mar Fernández De Gatta

1

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3 August 2017

Dolores Santos-Buelga

2

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3 August 2017

Alfonso Domínguez-Gil

3

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3 August 2017

María José García

4

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3 August 2017

1 January 2002

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Clinical Pharmacokinetics

3 August 2017

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3 August 2017

41

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3 August 2017

2

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3 August 2017

115-135

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https://scigraph.springernature.com/pub.10.2165/00003088-200241020-00004

3 August 2017

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Pharmacokinetics and pharmacodynamics of FK 506 in pediatric patients receiving living-related donor liver transplantations

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Tacrolimus in pediatric renal transplantation: a review

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Clinical variability of cyclosporine pharmacokinetics in adult and pediatric patients after renal, cardiac, hepatic, and bone-marrow transplants.

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12 December 2020

Differences in oral FK506 dose requirements between adult and pediatric liver transplant patients

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12 December 2020

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Antibody therapy as an induction regimen in pediatric renal transplantation

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Prevention of rejection in cardiac transplantation by blockade of the interleukin-2 receptor with a monoclonal antibody

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12 December 2020

Pharmacokinetics of tacrolimus (FK 506) in children and adolescents with renal transplants

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12 December 2020

Southwestern Internal Medicine Conference. New advances in immunosuppression therapy for renal transplantation

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12 December 2020

High variability of drug exposure: a biopharmaceutic risk factor for chronic rejection

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12 December 2020

Increased clearance of tacrolimus in children: need for higher doses and earlier initiation prior to bone marrow transplantation

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12 December 2020

Recommendations for bioequivalence testing of cyclosporine generics revisited

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12 December 2020

Cyclosporin pharmacokinetics in paediatric transplant recipients

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12 December 2020

Immunosuppressive drugs in paediatric liver transplantation

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12 December 2020

Advances in therapeutic drug monitoring for immunosuppressants: a review of sirolimus. Introduction and overview

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12 December 2020

Deoxyspergualin: mechanism of action and pharmacokinetics

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12 December 2020

Pharmacokinetics of mycophenolate mofetil are influenced by concomitant immunosuppression.

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12 December 2020

Therapeutic drug monitoring of immunosuppressant drugs.

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12 December 2020

The therapeutic use of azathioprine in renal transplantation

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12 December 2020

Long-term cyclosporin A pharmacokinetic profiles in pediatric renal transplant recipients

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12 December 2020

Muromonab CD-3: a review of its pharmacology, pharmacokinetics, and clinical use in transplantation

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12 December 2020

Population pharmacokinetics and exposure-response relationships for basiliximab in kidney transplantation. The U.S. Simulect Renal Transplant Study Group

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12 December 2020

The importance of thiopurine methyltransferase activity for the use of azathioprine in transplant recipients

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12 December 2020

A size standard for pharmacokinetics.

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12 December 2020

KIDNEY FUNCTION AFTER 1:1 CONVERSION TO THE CYCLOSPORINE MICROEMULSION FORMULATION IN CHILDREN WITH LIVER ALLOGRAFTS

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12 December 2020

6-Thioguanine nucleotide accumulation in erythrocytes during azathioprine treatment for systemic connective tissue diseases: a possible index for monitoring treatment

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12 December 2020

New immunosuppressive agents in pediatric renal transplantation

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12 December 2020

A critical appraisal of cyclosporine A pharmacokinetics in pediatric kidney transplantation using a microemulsion galenic formulation (Neoral)

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12 December 2020

Role of therapeutic drug monitoring of rapamycin

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12 December 2020

Canadian Consensus Meeting on cyclosporine monitoring: report of the consensus panel.

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12 December 2020

Sirolimus-induced thrombocytopenia and leukopenia in renal transplant recipients: risk factors, incidence, progression, and management

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12 December 2020

Comparison of pharmacokinetics of Neoral and Sandimmune in stable pediatric liver transplant recipients

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12 December 2020

Pharmacogenetics of acute azathioprine toxicity: relationship to thiopurine methyltransferase genetic polymorphism

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12 December 2020

Increased dosage requirement and rejection after Neoral conversion in pediatric liver transplant patients

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12 December 2020

Pharmacoeconomics of therapeutic drug monitoring in transplantation

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12 December 2020

Therapeutic drug monitoring of sirolimus: correlations with efficacy and toxicity

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12 December 2020

Sirolimus: continuing the evolution of transplant immunosuppression

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12 December 2020

Improved cyclosporine bioavailability in black pediatric liver transplant recipients after administration of the microemulsion formulation

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12 December 2020

Pharmacokinetics of mycophenolate mofetil in eight pediatric renal transplant patients

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12 December 2020

Clinical pharmacokinetics in organ transplant patients

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12 December 2020

Diltiazem retards the metabolism of oral prednisone with effects on T-cell markers

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12 December 2020

Methods for clinical monitoring of cyclosporin in transplant patients.

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12 December 2020

Tacrolimus, a new immunosuppressant--a review of the literature

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12 December 2020

Mycophenolate mofetil for rescue therapy in acute renal transplant rejection in children should always be monitored by measurement of trough concentration

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12 December 2020

OKT3 therapy increases cyclosporine blood levels

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12 December 2020

Pharmacokinetics of cyclosporine in pediatric long-term liver transplant recipients converted from Sandimmun to Neoral

1 reference

12 December 2020

Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings

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12 December 2020

Clinical use of mizoribine (Bredinin) and pharmacologic monitoring assessment in renal transplantation

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12 December 2020

Target concentration strategy for cyclosporin monitoring

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12 December 2020

The use of therapeutic drug monitoring to optimise immunosuppressive therapy

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12 December 2020

Reduced variability of neoral pharmacokinetic studies in pediatric renal transplantation

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12 December 2020

Tacrolimus: a further update of its pharmacology and therapeutic use in the management of organ transplantation

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12 December 2020

Cyclosporin A monitoring in Australia: consensus recommendations

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12 December 2020

Biological effects of cyclosporin A: A new antilymphocytic agent

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12 December 2020

Population pharmacokinetics of sirolimus in kidney transplant patients

1 reference

12 December 2020

Optimization of cyclosporine therapy with new therapeutic drug monitoring strategies: report from the International Neoral TDM Advisory Consensus Meeting (Vancouver, November 1997).

1 reference

12 December 2020

Steady-state pharmacokinetics of cyclosporine in renal transplant patients: does an influence of age or body weight exist?

1 reference

12 December 2020

Abbreviated cyclosporine AUCs on Neoral--the search continues!

1 reference

12 December 2020

Clinical pharmacokinetics of tacrolimus

1 reference

12 December 2020

Pharmacokinetics of mycophenolic acid (MPA) and determinants of MPA free fraction in pediatric and adult renal transplant recipients. German Study group on Mycophenolate Mofetil Therapy in Pediatric Renal Transplant Recipients

1 reference

12 December 2020

Therapeutic drug monitoring of cyclosporin. Practical applications and limitations

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12 December 2020

Study of circadian variation of cyclosporine pharmacokinetics

1 reference

12 December 2020

Recent advances in cyclosporine pharmacokinetics

1 reference

12 December 2020

The pharmacokinetic-pharmacodynamic relationship for mycophenolate mofetil in renal transplantation

1 reference

12 December 2020

Age-dependent cyclosporine: pharmacokinetics in marrow transplant recipients

1 reference

12 December 2020

Lake Louise Consensus Conference on cyclosporin monitoring in organ transplantation: report of the consensus panel.

1 reference

12 December 2020

Monitoring of azathioprine treatment by determination of 6-thioguanine nucleotide concentrations in erythrocytes

1 reference

12 December 2020

Absorption characteristics of a microemulsion formulation of cyclosporine in de novo pediatric liver transplant recipients

1 reference

12 December 2020

Sirolimus: a new agent for prevention of renal allograft rejection

1 reference

12 December 2020

Covariate effects on the apparent clearance of tacrolimus in paediatric liver transplant patients undergoing conversion therapy.

1 reference

12 December 2020

Comparative methylprednisolone pharmacokinetics in renal transplant patients receiving double- or triple-drug immunosuppression

1 reference

12 December 2020

Muromonab-CD3 and antithymocyte globulin in renal transplantation

1 reference

12 December 2020

Efficacy of Neoral in the immediate postoperative period in children post-liver transplantation.

1 reference

12 December 2020

Pharmacokinetics of methylprednisolone and rejection episodes in kidney transplant patients

1 reference

12 December 2020

Pharmacokinetics of deflazacort in renal transplanted and hemodialyzed children.

1 reference

12 December 2020

Cyclosporin A (Neoral) in pediatric organ transplantation. Neoral Pediatric Study Group

1 reference

12 December 2020

The use of tacrolimus in pediatric liver transplantation

1 reference

12 December 2020

Pharmacokinetics of mycophenolic acid (MPA) and free MPA in paediatric renal transplant recipients--a multicentre study. The German Study Group on Mycophenolate Mofetil (MMF) Therapy

1 reference

12 December 2020

Clinical pharmacokinetics of Neoral in pediatric recipients of primary liver transplants

1 reference

12 December 2020

Rapamycin: distribution, pharmacokinetics and therapeutic range investigations: an update

1 reference

12 December 2020

Impact of absorption profiling on efficacy and safety of cyclosporin therapy in transplant recipients.

1 reference

12 December 2020

Pharmacokinetics of prednisolone during administration of sirolimus in patients with renal transplants

1 reference

12 December 2020

Screening for basiliximab exposure-response relationships in renal allotransplantation

1 reference

12 December 2020

Limited sampling model for area-under-the-curve monitoring in pediatric patients receiving either Sandimmune or Neoral cyclosporin A oral formulations.

1 reference

12 December 2020

Experience with daclizumab in liver transplantation: renal transplant dosing without calcineurin inhibitors is insufficient to prevent acute rejection in liver transplantation

1 reference

12 December 2020

Sandimmune to Neoral conversion and value of abbreviated AUC monitoring in stable pediatric kidney transplant recipients

1 reference

12 December 2020

Cyclosporin clinical pharmacokinetics

1 reference

12 December 2020

Comparative study of cyclosporine and FK 506 dosage requirements in adult and pediatric orthotopic liver transplant patients

1 reference

12 December 2020

Improving the therapeutic monitoring of cyclosporin A

1 reference

12 December 2020

Comparative clinical pharmacokinetics of tacrolimus in paediatric and adult patients

1 reference

12 December 2020

Evaluation of dose-related pharmacokinetics and pharmacodynamics of prednisolone in man

1 reference

12 December 2020

Neoral induction in pediatric renal transplantation

1 reference

12 December 2020

Pharmacokinetics of tacrolimus (FK506) in paediatric liver transplant recipients.

1 reference

12 December 2020

FK506 (tacrolimus) compared with cyclosporine for primary immunosuppression after pediatric liver transplantation. Results from the U.S. Multicenter Trial.

1 reference

12 December 2020

The pediatric nephrologist's dilemma: growth after renal transplantation and its interaction with age as a possible immunologic variable

1 reference

12 December 2020

Monitoring glucocorticoid therapy: a pharmacokinetic approach

1 reference

12 December 2020

6-Mercaptopurine pharmacokinetics after use of azathioprine in renal transplant recipients with intermediate or high thiopurine methyl transferase activity phenotype

1 reference

12 December 2020

Area under the concentration curve values in pediatric liver transplant recipients on cyclosporin microemulsion formulation.

1 reference

12 December 2020

Pharmacokinetics of cyclosporine as a function of energy--protein deficiency in children with chronic renal failure

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12 December 2020

Pharmacokinetics of an oral solution of the microemulsion formulation of cyclosporine in maintenance pediatric liver transplant recipients.

1 reference

12 December 2020

Blood distribution and single-dose pharmacokinetics of leflunomide

1 reference

12 December 2020

Therapeutic strategies for optimal use of novel immunosuppressants

1 reference

12 December 2020

Enhanced oral cyclosporine absorption with water-soluble vitamin E early after liver transplantation.

1 reference

12 December 2020

NONMEM population pharmacokinetic modeling of orally administered cyclosporine from routine drug monitoring data after heart transplantation

1 reference

12 December 2020

Safety, tolerability, and pharmacokinetic actions of diltiazem in pediatric liver transplant recipients on cyclosporine

1 reference

12 December 2020

Bioavailability of two oral formulations of cyclosporin A in uremic children before renal transplantation

1 reference

12 December 2020

The monitoring of immunosuppressive drugs: a pharmacodynamic approach

1 reference

12 December 2020

New immunosuppressive drugs in organ transplantation

1 reference

12 December 2020

Pharmacokinetics of azathioprine after repeated oral and single intravenous administration

1 reference

12 December 2020

Pharmacokinetics of cyclosporine after renal transplant in children

1 reference

12 December 2020

Optimal time points for the prediction of the area-under-the-curve in liver transplant patients receiving tacrolimus

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12 December 2020

1 reference

12 December 2020

Pharmacology of immunosuppressive medications used in renal diseases and transplantation

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12 December 2020

Cyclosporine A monitoring in children: abbreviated area under curve formulas and C2 level

1 reference

12 December 2020

Pharmacokinetics, dosing principles, and blood level monitoring of FK506.

1 reference

12 December 2020

Update of current immunosuppressive drugs used in clinical organ transplantation

1 reference

12 December 2020

Sandimmun and Neoral treatment: pharmacokinetics and kidney function in paediatric and adolescent renal transplant

1 reference

12 December 2020

Monitoring of tacrolimus as rescue therapy in pediatric liver transplantation

1 reference

12 December 2020

Trends in immunosuppressive therapy: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)

1 reference

12 December 2020

Disposition and immunodynamics of basiliximab in liver allograft recipients.

1 reference

12 December 2020

Phase I safety and pharmacokinetic studies of brequinar sodium after single ascending oral doses in stable renal, hepatic, and cardiac allograft recipients

1 reference

12 December 2020

Limited sampling strategy for mycophenolic acid area under the curve

1 reference

12 December 2020

Consensus document: therapeutic monitoring of tacrolimus (FK-506).

1 reference

12 December 2020

Liver transplantation in children: long-term outcome and quality of life

1 reference

12 December 2020

Long-term survivors of pediatric heart transplantation: a multicenter report of sixty-eight children who have survived longer than five years

1 reference

12 December 2020

Pharmacokinetics and metabolism of sirolimus

1 reference

12 December 2020

Cyclosporin A in patients receiving renal allografts from cadaver donors

1 reference

12 December 2020

Consensus statements on the optimal use of cyclosporine in pediatric patients

1 reference

12 December 2020

Constructing a prediction interval for time to reach a threshold concentration based on a population pharmacokinetic analysis: an application to basiliximab in renal transplantation.

1 reference

12 December 2020

10.2165/00003088-200241020-00004

Identifiers

DOI

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Dimensions Publication ID

3 August 2017

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