(Q34559498)

3 August 2017

title

Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites (English)

1 reference

3 August 2017

Yun Xie

1

1 reference

3 August 2017

Andrew V Dix

series ordinal

2

1 reference

3 August 2017

Yitzhak Tor

series ordinal

3

1 reference

3 August 2017

language of work or name

English

0 references

publication date

13 May 2010

1 reference

3 August 2017

published in

Chemical Communications

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3 August 2017

volume

46

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3 August 2017

issue

30

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3 August 2017

page(s)

5542-5544

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FRET enabled real time detection of RNA-small molecule binding

3 August 2017

cites work

1 reference

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The use of ribosomal crystal structures in antibiotic drug design.

7 July 2018

1 reference

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Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria

7 July 2018

1 reference

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Negamycin Binds to the Wall of the Nascent Chain Exit Tunnel of the 50S Ribosomal Subunit

7 July 2018

1 reference

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Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization

7 July 2018

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7 July 2018

1 reference

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The ribosomal A-site as an inspiration for the design of RNA binders

7 July 2018

1 reference

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Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity.

7 July 2018

1 reference

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Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

7 July 2018

1 reference

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Antibiotics targeting ribosomes: resistance, selectivity, synergism and cellular regulation

7 July 2018

1 reference

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Improving on nature: antibiotics that target the ribosome

7 July 2018

1 reference

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Defining the basis for the specificity of aminoglycoside-rRNA recognition: a comparative study of drug binding to the A sites of Escherichia coli and human rRNA.

7 July 2018

1 reference

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RNA as a Drug Target: The Case of Aminoglycosides

7 July 2018

1 reference

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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

7 July 2018

1 reference

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Targeting RNA with small-molecule drugs: therapeutic promise and chemical challenges

7 July 2018

1 reference

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Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site

7 July 2018

1 reference

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Recognition of cognate transfer RNA by the 30S ribosomal subunit

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Structural basis for selectivity and toxicity of ribosomal antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Structural origins of aminoglycoside specificity for prokaryotic ribosomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Basis for prokaryotic specificity of action of aminoglycoside antibiotics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Ribosomes and translation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Mechanism of action of negamycin in Escherichia coli K12. I. Inhibition of initiation of protein synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Aminoglycoside binding to human and bacterial A-Site rRNA decoding region constructs

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035430

Specificity of aminoglycoside antibiotics for the A-site of the decoding region of ribosomal RNA

27 October 2018

1 reference

12 December 2020

Aminoglycoside antibiotics and eukaryotic protein synthesis: stimulation of errors in the translation of natural messengers in extracts of cultured human cells

1 reference

12 December 2020

Aminoglycoside antibiotics and eukaryotic protein synthesis: structure--function relationships in the stimulation of misreading with a wheat embryo system

1 reference

12 December 2020

Negamycin, a novel hydrazide antibiotic

1 reference

12 December 2020

Targeting RNA with Small Molecules

1 reference

12 December 2020

Identifiers

DOI

10.1039/C0CC00423E

1 reference

3 August 2017

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3 August 2017

1 reference