(Q34565310)

3 August 2017

title

Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions (English)

1 reference

3 August 2017

Takehiko Yokomizo

5

0 references

Timothy Hla

object named as

Timothy Hla

7

0 references

Jeremiah Stitham

3

object named as

Jeremiah Stitham

1 reference

3 August 2017

Hideru Obinata

1

1 reference

3 August 2017

Sarah Gutkind

2

1 reference

3 August 2017

Toshiaki Okuno

4

1 reference

3 August 2017

John Hwa

6

1 reference

3 August 2017

language of work or name

1 reference

7 October 2014

1 reference

Journal of Lipid Research

3 August 2017

published in

1 reference

3 August 2017

volume

55

1 reference

3 August 2017

issue

12

1 reference

3 August 2017

page(s)

2665-2675

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Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P)

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Second generation S1P pathway modulators: research strategies and clinical developments.

7 July 2018

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Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

7 July 2018

1 reference

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Sphingosine-1-phosphate and its receptors: structure, signaling, and influence

7 July 2018

1 reference

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Restructuring G-protein- coupled receptor activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Fine-tuning S1P therapeutics

7 July 2018

1 reference

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Flow-regulated endothelial S1P receptor-1 signaling sustains vascular development

7 July 2018

1 reference

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Helix 8 of leukotriene B4 receptor 1 inhibits ligand-induced internalization

7 July 2018

1 reference

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Assessment of sphingosine-1-phosphate activity in biological samples by receptor internalization and adherens junction formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Crystal structure of a lipid G protein-coupled receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs

7 July 2018

1 reference

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Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Lifting the lid on GPCRs: the role of extracellular loops

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Sphingosine 1-phosphate in coagulation and inflammation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

N-linked glycosylation of protease-activated receptor-1 second extracellular loop: a critical determinant for ligand-induced receptor activation and internalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Anti-atherogenic actions of high-density lipoprotein through sphingosine 1-phosphate receptors and scavenger receptor class B type I.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

The vascular S1P gradient-cellular sources and biological significance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

HDL serves as a S1P signaling platform mediating a multitude of cardiovascular effects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

N-glycans of sphingosine 1-phosphate receptor Edg-1 regulate ligand-induced receptor internalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

7 July 2018

https://api.crossref.org/works/10.1194%2FJLR.P054163

Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

A helix propensity scale based on experimental studies of peptides and proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

The inducible G protein-coupled receptor edg-1 signals via the G(i)/mitogen-activated protein kinase pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4242458

The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.

7 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.P054163

S1P1 inhibits sprouting angiogenesis during vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.P054163

Engagement of S1P₁-degradative mechanisms leads to vascular leak in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.P054163

Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.P054163

The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.P054163

G-protein-coupled receptor S1P1 acts within endothelial cells to regulate vascular maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.P054163

21 January 2018

Identifiers

DOI

10.1194/JLR.P054163

1 reference

3 August 2017

1 reference

3 August 2017

1 reference