(Q34568264)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Linked thioredoxin-glutathione systems in platyhelminth parasites: alternative pathways for glutathione reduction and deglutathionylation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

1 reference

1

1 reference

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15 January 2020

4

Vadim N Gladyshev

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

2

Ana Denicola

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Stefano M Marino

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Gustavo Salinas

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

language of work or name

English

0 references

publication date

4 November 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

number of pages

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

4959-4967

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

Mapping the Catalytic Cycle of Schistosoma mansoni Thioredoxin Glutathione Reductase by X-ray Crystallography

15 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Structural and kinetic analysis of Saccharomyces cerevisiae thioredoxin Trx1: implications for the catalytic mechanism of GSSG reduced by the thioredoxin system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Structural aspects of the distinct biochemical properties of glutaredoxin 1 and glutaredoxin 2 from Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Platyhelminth mitochondrial and cytosolic redox homeostasis is controlled by a single thioredoxin glutathione reductase and dependent on selenium and glutathione.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Assessment of production conditions for efficient use of Escherichia coli in high-yield heterologous recombinant selenoprotein synthesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

The disulfide redox system of Schistosoma mansoni and the importance of a multifunctional enzyme, thioredoxin glutathione reductase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Solution structure of Escherichia coli glutaredoxin-2 shows similarity to mammalian glutathione-S-transferases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Structure, dynamics and electrostatics of the active site of glutaredoxin 3 from Escherichia coli: comparison with functionally related proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Selenoprotein oxidoreductase with specificity for thioredoxin and glutathione systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Overexpression of wild type and SeCys/Cys mutant of human thioredoxin reductase in E. coli: the role of selenocysteine in the catalytic activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

NMR structure of oxidized glutaredoxin 3 from Escherichia coli

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

High-level expression in Escherichia coli of selenocysteine-containing rat thioredoxin reductase utilizing gene fusions with engineered bacterial-type SECIS elements and co-expression with the selA, selB and selC genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

NMR structure of oxidized Escherichia coli glutaredoxin: Comparison with reduced E. coli glutaredoxin and functionally related proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Alternative mRNAs arising from trans-splicing code for mitochondrial and cytosolic variants of Echinococcus granulosus thioredoxin Glutathione reductase

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170761

Purification, characterization and kinetic properties of the multifunctional thioredoxin-glutathione reductase from Taenia crassiceps metacestode (cysticerci).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170761

Reaction mechanism and regulation of mammalian thioredoxin/glutathione reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170761

In vitro killing action of auranofin on Taenia crassiceps metacestode (cysticerci) and inactivation of thioredoxin-glutathione reductase (TGR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170761

S-nitrosation versus S-glutathionylation of protein sulfhydryl groups by S-nitrosoglutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170761

The thioredoxin system of the malaria parasite Plasmodium falciparum. Glutathione reduction revisited.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.170761

Protein denitrosylation: enzymatic mechanisms and cellular functions.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

Protein sequence alignments: a strategy for the hierarchical analysis of residue conservation.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037608

27 October 2018

Glutathione reductase

1 reference

12 December 2020

S-nitrosoglutathione is cleaved by the thioredoxin system with liberation of glutathione and redox regulating nitric oxide

1 reference

12 December 2020

The path of unspecific incorporation of selenium in Escherichia coli

1 reference

12 December 2020

Preparation and assay of mammalian thioredoxin and thioredoxin reductase

1 reference

12 December 2020

Insights into deglutathionylation reactions. Different intermediates in the glutaredoxin and protein disulfide isomerase catalyzed reactions are defined by the gamma-linkage present in glutathione

1 reference

12 December 2020

Rat liver thioredoxin and thioredoxin reductase: purification and characterization

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.170761

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21051543%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

21051543

1 reference