(Q34568391)

3 August 2017

title

Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain (English)

1 reference

3 August 2017

1

Jan Terje Andersen

1 reference

3 August 2017

Rikard Pehrson

2

1 reference

3 August 2017

Vladimir Tolmachev

3

1 reference

3 August 2017

Muluneh Bekele Daba

4

1 reference

3 August 2017

Lars Abrahmsén

5

1 reference

3 August 2017

Caroline Ekblad

6

1 reference

3 August 2017

language of work or name

English

0 references

publication date

7 December 2010

1 reference

Journal of Biological Chemistry

3 August 2017

published in

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3 August 2017

volume

286

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3 August 2017

issue

7

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3 August 2017

page(s)

5234-5241

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Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

FcRn binding properties of an abnormal truncated analbuminemic albumin variant

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Biodistribution of a bispecific single-chain diabody and its half-life extended derivatives

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Conditional deletion of the MHC class I-related receptor FcRn reveals the sites of IgG homeostasis in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Ligand binding and antigenic properties of a human neonatal Fc receptor with mutation of two unpaired cysteine residues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Discovering and improving novel peptide therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Dependence of antibody-mediated presentation of antigen on FcRn

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Engineering of a femtomolar affinity binding protein to human serum albumin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Anti-serum albumin domain antibodies for extending the half-lives of short lived drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Fc-based cytokines : prospects for engineering superior therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Albinterferon alpha-2b: a genetic fusion protein for the treatment of chronic hepatitis C.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

FcRn: the neonatal Fc receptor comes of age.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Radionuclide therapy of HER2-positive microxenografts using a 177Lu-labeled HER2-specific Affibody molecule.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Perspective-- FcRn transports albumin: relevance to immunology and medicine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Tumor imaging using a picomolar affinity HER2 binding affibody molecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Comparative in vivo evaluation of technetium and iodine labels on an anti-HER2 affibody for single-photon imaging of HER2 expression in tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Engineering novel binding proteins from nonimmunoglobulin domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Crystal structure and biological implications of a bacterial albumin binding module in complex with human serum albumin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Selection and characterization of HER2/neu-binding affibody ligands

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Visualizing the site and dynamics of IgG salvage by the MHC class I-related receptor, FcRn.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Site-specific PEGylation of a lysine-deficient TNF-alpha with full bioactivity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Effect of pegylation on pharmaceuticals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Therapeutic antibodies for human diseases at the dawn of the twenty-first century

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Pharmaceutical strategies utilizing recombinant human serum albumin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Major oncogenes and tumor suppressor genes involved in epithelial ovarian cancer (review).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Interstitial exclusion of IgG in rat tissues estimated by continuous infusion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Metabolism of immunoglobulins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Interstitial exclusion of albumin in rat tissues measured by a continuous infusion method

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3037636

Development trends for therapeutic antibody fragments

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

Prolonged in vivo residence times of antibody fragments associated with albumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

Use of an albumin-binding domain for the selective immobilisation of recombinant capture antibody fragments on ELISA plates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

Imaging tumors with an albumin-binding Fab, a novel tumor-targeting agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

Albumin binding as a general strategy for improving the pharmacokinetics of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

The pharmacokinetics of an albumin-binding Fab (AB.Fab) can be modulated as a function of affinity for albumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

Albumin binding to FcRn: distinct from the FcRn-IgG interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH-dependent binding to albumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164848

21 January 2018

1 reference

12 December 2020

Extended in vivo half-life of human soluble complement receptor type 1 fused to a serum albumin-binding receptor

1 reference

12 December 2020

Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells

1 reference

12 December 2020

A novel tri-functional antibody fusion protein with improved pharmacokinetic properties generated by fusing a bispecific single-chain diabody with an albumin-binding domain from streptococcal protein G

1 reference

12 December 2020

Anti-serum albumin domain antibodies in the development of highly potent, efficacious and long-acting interferon

1 reference

12 December 2020

Interstitial fluid pressure, composition of interstitium, and interstitial exclusion of albumin in hypothyroid rats

1 reference

12 December 2020

Albugranin, a recombinant human granulocyte colony stimulating factor (G-CSF) genetically fused to recombinant human albumin induces prolonged myelopoietic effects in mice and monkeys

1 reference

12 December 2020

Evidence to support the cellular mechanism involved in serum IgG homeostasis in humans

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.164848

1 reference

3 August 2017

1 reference

3 August 2017

1 reference