(Q34568708)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

review article

1 reference

title

Interleukin-12 in anti-tumor immunity and immunotherapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

interleukin-12-interleukin-12 receptor complex

8 December 2019

main subject

interleukins

0 references

1 reference

Gene Ontology release 2020-05-02

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

2

Giorgio Trinchieri

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

publication date

1 April 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

Cytokine and Growth Factor Reviews

8 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

155-168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

8 December 2019

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The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells

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7 January 2021

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

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7 January 2021

Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells

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7 January 2021

Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist

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7 January 2021

Biosynthesis and posttranslational regulation of human IL-12.

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7 January 2021

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

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7 January 2021

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

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7 January 2021

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes

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7 January 2021

Antitumor and antimetastatic activity of interleukin 12 against murine tumors

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7 January 2021

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

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7 January 2021

Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12

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7 January 2021

The anti-tumor activity of IL-12: mechanisms of innate immunity that are model and dose dependent

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7 January 2021

Different requirements for alpha-galactosylceramide and recombinant IL-12 antitumor activity in the treatment of C-26 colon carcinoma hepatic metastases.

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7 January 2021

CD4 T cells inhibit in vivo the CD8-mediated immune response against murine colon carcinoma cells transduced with interleukin-12 genes

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7 January 2021

Regulatory T cells in the control of immune pathology.

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7 January 2021

Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor

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7 January 2021

Cytokines, tumour-cell death and immunogenicity: a question of choice

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7 January 2021

Antitumor Efficacy of Adenocarcinoma Cells Engineered to Produce Interleukin 12 (IL-12) or Other Cytokines Compared With Exogenous IL-12

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7 January 2021

Interleukin 12 synergizes with B7/CD28 interaction in inducing efficient proliferation and cytokine production of human T cells

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7 January 2021

B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation

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7 January 2021

The adjuvant effect of interleukin-12 in a vaccine against Leishmania major.

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7 January 2021

IL-12 as an adjuvant for cell-mediated immunity

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7 January 2021

Influence of interleukin 12 on p53 peptide vaccination against established Meth A sarcoma

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7 January 2021

Interleukin-12 as an adjuvant for cancer immunotherapy

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7 January 2021

Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect

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7 January 2021

Inhibition of angiogenesis in vivo by interleukin 12.

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7 January 2021

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo

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7 January 2021

A Role for the Interferon-Inducible Protein 10 in Inhibition of Angiogenesis by Interleukin-12

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7 January 2021

Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12

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7 January 2021

Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis

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7 January 2021

Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis

1 reference

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7 January 2021

Oxygen dependence of cellular uptake of EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl)a cet amide] : analysis of drug adducts by fluorescent antibodies vs bound radioactivity

1 reference

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7 January 2021

IFN-gamma and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy

1 reference

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7 January 2021

The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig

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7 January 2021

Cell cycle-dependent expression of CXC chemokine receptor 3 by endothelial cells mediates angiostatic activity

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7 January 2021

Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells

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7 January 2021

IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk

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7 January 2021

Interleukin 12-mediated prevention of spontaneous mammary adenocarcinomas in two lines of Her-2/neu transgenic mice.

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7 January 2021

Effects of high dose raloxifene in selected patients with advanced breast carcinoma.

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7 January 2021

Tamoxifen for the prevention of breast cancer

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7 January 2021

IL-12 treatment of endogenously arising murine brain tumors

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7 January 2021

Effect of interleukin 12 on tumor induction by 3-methylcholanthrene

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7 January 2021

Differential tumor surveillance by natural killer (NK) and NKT cells.

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7 January 2021

CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides

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7 January 2021

The natural killer T (NKT) cell ligand alpha-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells

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7 January 2021

Toll meets bacterial CpG-DNA.

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7 January 2021

Evaluation of recombinant human interleukin-12 in patients with recurrent or refractory ovarian cancer: a gynecologic oncology group study

1 reference

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7 January 2021

Down-regulation of the pharmacokinetic-pharmacodynamic response to interleukin-12 during long-term administration to patients with renal cell carcinoma and evaluation of the mechanism of this “adaptive response” in mice

1 reference

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7 January 2021

Randomized multicenter phase II trial of subcutaneous recombinant human interleukin-12 versus interferon-alpha 2a for patients with advanced renal cell carcinoma

1 reference

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7 January 2021

Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: outcome of a phase I study

1 reference

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7 January 2021

Effects of interleukin-12 on the immune response to a multipeptide vaccine for resected metastatic melanoma

1 reference

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7 January 2021

Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency

1 reference

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7 January 2021

Inherited interleukin 12 deficiency in a child with bacille Calmette-Guérin and Salmonella enteritidis disseminated infection

1 reference

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7 January 2021

10.1016/S1359-6101(01)00032-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11900991%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference