(Q34569564)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures (English)

1 reference

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23 February 2020

5

1 reference

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23 February 2020

Opher Gileadi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Eli Rothenberg

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Ian D Hickson

7

0 references

author name string

Sujoy Chatterjee

1

1 reference

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23 February 2020

Jennifer Zagelbaum

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Pavel Savitsky

3

1 reference

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23 February 2020

Andreas Sturzenegger

4

1 reference

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23 February 2020

Pavel Janscak

6

1 reference

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23 February 2020

language of work or name

English

0 references

publication date

24 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

published in

Nature Communications

1 reference

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23 February 2020

volume

5

1 reference

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23 February 2020

page(s)

5556

1 reference

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https://scigraph.springernature.com/pub.10.1038/ncomms6556

23 February 2020

exact match

0 references

cites work

RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP

1 reference

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Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs.

7 July 2018

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Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2

7 July 2018

1 reference

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Periodic DNA patrolling underlies diverse functions of Pif1 on R-loops and G-rich DNA.

7 July 2018

1 reference

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Human RecQ helicases in DNA repair, recombination, and replication.

7 July 2018

1 reference

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G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding

7 July 2018

1 reference

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Structure of the RecQ C-terminal domain of human Bloom syndrome protein

7 July 2018

1 reference

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Genomes and G-quadruplexes: for better or for worse.

7 July 2018

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Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability

7 July 2018

1 reference

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Pif1 family helicases suppress genome instability at G-quadruplex motifs

7 July 2018

1 reference

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Neisseria gonorrhoeae RecQ helicase HRDC domains are essential for efficient binding and unwinding of the pilE guanine quartet structure required for pilin antigenic variation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells

7 July 2018

1 reference

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RecQ Helicases: Conserved Guardians of Genomic Integrity.

7 July 2018

1 reference

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DNA secondary structures: stability and function of G-quadruplex structures

7 July 2018

1 reference

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POT1-TPP1 regulates telomeric overhang structural dynamics.

7 July 2018

1 reference

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Small-molecule-induced DNA damage identifies alternative DNA structures in human genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Insight into helicase mechanism and function revealed through single-molecule approaches

7 July 2018

1 reference

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Structure, location and interactions of G‐quadruplexes

7 July 2018

1 reference

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G‐quadruplex nucleic acids and human disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Structure and function of the regulatory HRDC domain from human Bloom syndrome protein

7 July 2018

1 reference

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High-throughput production of human proteins for crystallization: the SGC experience.

7 July 2018

1 reference

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Unwinding the functions of the Pif1 family helicases.

7 July 2018

1 reference

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Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

7 July 2018

1 reference

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The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

BLM helicase measures DNA unwound before switching strands and hRPA promotes unwinding reinitiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase delta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Baculovirus expression vector system: an emerging host for high-throughput eukaryotic protein expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Replication fork regression in vitro by the Werner syndrome protein (WRN): holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Human replication protein A unfolds telomeric G-quadruplexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Analysis of single-molecule FRET trajectories using hidden Markov modeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Extreme conformational diversity in human telomeric DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The HRDC domain of BLM is required for the dissolution of double Holliday junctions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Prevalence of quadruplexes in the human genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Highly prevalent putative quadruplex sequence motifs in human DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Helix formation by guanylic acid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Characterization and mutational analysis of the RecQ core of the bloom syndrome protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Substrate-specific inhibition of RecQ helicase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The Bloom's syndrome gene product is a 3'-5' DNA helicase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Monovalent cation-induced structure of telomeric DNA: the G-quartet model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

Fork sensing and strand switching control antagonistic activities of RecQ helicases

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS6556

A conserved G4 DNA binding domain in RecQ family helicases.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS6556

High throughput production of recombinant human proteins for crystallography

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4243535

The Bloom's syndrome helicase unwinds G4 DNA

27 October 2018

1 reference

12 December 2020

Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n

1 reference

12 December 2020

Role for BLM in replication-fork restart and suppression of origin firing after replicative stress

1 reference

12 December 2020

Single-molecule FRET analysis of helicase functions

1 reference

12 December 2020

G-quadruplex hinders translocation of BLM helicase on DNA: a real-time fluorescence spectroscopic unwinding study and comparison with duplex substrates

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS6556

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

23 February 2020

ADS bibcode

2014NatCo...5.5556C

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

25418155

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25418155%20AND%20SRC:MED&resulttype=core&format=json