(Q34574703)

3 August 2017

Deimination of membrane-bound myelin basic protein in multiple sclerosis exposes an immunodominant epitope (English)

1 reference

3 August 2017

0 references

George Harauz

3

0 references

author name string

Abdiwahab A Musse

series ordinal

1

1 reference

PubMed ID

16537438

3 August 2017

Joan M Boggs

series ordinal

2

1 reference

PubMed ID

16537438

3 August 2017

language of work or name

English

0 references

publication date

9 March 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

1 reference

3 August 2017

103

1 reference

3 August 2017

12

1 reference

3 August 2017

4422-4427

1 reference

Major T-cell responses in multiple sclerosis.

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Solution NMR structure of an immunodominant epitope of myelin basic protein. Conformational dependence on environment of an intrinsically unstructured protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Molecules affecting myelin stability: a novel hypothesis regarding the pathogenesis of multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Synergistic interactions of lipids and myelin basic protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Myelin basic protein-diverse conformational states of an intrinsically unstructured protein and its roles in myelin assembly and multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Multiple sclerosis: etiological mechanisms and future directions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Neuropathology of multiple sclerosis-new concepts.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

A functional and structural basis for TCR cross-reactivity in multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Kinetic profiles of cerebrospinal fluid anti-MBP in response to intravenous MBP synthetic peptide DENP(85)VVHFFKNIVTP(96)RT in multiple sclerosis patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Identifying conformational changes with site-directed spin labeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Substrate-induced exposure of an energy-coupling motif of a membrane transporter

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Cryoelectron microscopy of protein-lipid complexes of human myelin basic protein charge isomers differing in degree of citrullination.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Highly deiminated isoform of myelin basic protein from multiple sclerosis brain causes fragmentation of lipid vesicles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Axonal transection in the lesions of multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Binding of myelin basic protein peptides to human histocompatibility leukocyte antigen class II molecules and their recognition by T cells from multiple sclerosis patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Determination of the distance between two spin labels attached to a macromolecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Myelin in multiple sclerosis is developmentally immature

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

The isolation, characterization, and lipid-aggregating properties of a citrulline containing myelin basic protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Cells producing antibodies specific for myelin basic protein region 70-89 are predominant in cerebrospinal fluid from patients with multiple sclerosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Rapid release and unusual stability of immunodominant peptide 45-89 from citrullinated myelin basic protein.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

An Arg/Lys-->Gln mutant of recombinant murine myelin basic protein as a mimic of the deiminated form implicated in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

Membrane-anchoring and charge effects in the interaction of myelin basic protein with lipid bilayers studied by site-directed spin labeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

An immunodominant epitope of myelin basic protein is an amphipathic alpha-helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

Multiple sclerosis: an important role for post-translational modifications of myelin basic protein in pathogenesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450187

Deimination of Myelin Basic Protein. 2. Effect of Methylation of MBP on Its Deimination by Peptidylarginine Deiminase†

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

Characterization of a Recombinant Murine 18.5-kDa Myelin Basic Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0509158103

Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein

21 January 2018

1 reference

12 December 2020

Effect of posttranslational modifications to myelin basic protein on its ability to aggregate acidic lipid vesicles

1 reference

12 December 2020

Expansion by self antigen is necessary for the induction of experimental autoimmune encephalomyelitis by T cells primed with a cross-reactive environmental antigen

1 reference

12 December 2020

Immunology of multiple sclerosis

1 reference

12 December 2020

1 reference

12 December 2020

Multilamellar packing of myelin modeled by lipid-bound MBP

1 reference

12 December 2020

Site-directed spin labeling of proteins. Applications to diphtheria toxin

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0509158103

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference

PubMed ID

16537438