(Q34575673)

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Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase.

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17 January 2020

Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase (English)

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17 January 2020

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8

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17 January 2020

Vern L. Schramm

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Vern L Schramm

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17 January 2020

Thomas J Belbin

4

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Thomas J Belbin

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17 January 2020

9

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Chandan Guha

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17 January 2020

Maria B Cassera

3

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Maria B Cassera

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17 January 2020

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author name string

Indranil Basu

1

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17 January 2020

Joseph Locker

2

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17 January 2020

Emilio F Merino

5

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17 January 2020

Xinyuan Dong

6

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17 January 2020

Ivan Hemeon

7

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17 January 2020

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6 December 2010

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17 January 2020

number of pages

10

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Journal of Biological Chemistry

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17 January 2020

286

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17 January 2020

6

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17 January 2020

4902-4911

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17 January 2020

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

1 reference

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7 July 2018

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1 reference

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Cancer chemoprevention locks onto a new polyamine metabolic target

1 reference

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7 July 2018

Polyamine catabolism and disease

1 reference

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7 July 2018

Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma

1 reference

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7 July 2018

Cancer statistics, 2009

1 reference

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Polyamine biosynthesis impacts cellular folate requirements necessary to maintain S-adenosylmethionine and nucleotide pools.

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New TNM classification for non-small-cell lung cancer

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Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry

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7 July 2018

A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers

1 reference

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7 July 2018

Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039339

7 July 2018

Polyamines and cancer: old molecules, new understanding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039339

7 July 2018

Methylthioadenosine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039339

7 July 2018

DNA demethylation and cancer: therapeutic implications.

1 reference

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7 July 2018

Methylthioadenosine phosphorylase, a gene frequently codeleted with p16(cdkN2a/ARF), acts as a tumor suppressor in a breast cancer cell line

1 reference

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7 July 2018

Present and future treatment of advanced non-small cell lung cancer

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7 July 2018

Identification of genes periodically expressed in the human cell cycle and their expression in tumors

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7 July 2018

Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039339

7 July 2018

S-Adenosylmethionine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039339

7 July 2018

Development of difluoromethylornithine (DFMO) as a chemoprevention agent.

1 reference

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7 July 2018

Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21

1 reference

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7 July 2018

Inhibition by 5'-methylthioadenosine of cell growth and tyrosine kinase activity stimulated by fibroblast growth factor receptor in human gliomas

1 reference

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7 July 2018

Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis

1 reference

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Effect of several inhibitors of enzymatic DNA methylation on thein vivomethylation of different classes of DNA sequences in a cultured human cell line

1 reference

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7 July 2018

Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.

1 reference

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Methylthioadenosine, a potent inhibitor of spermine synthase from bovine brain

1 reference

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1 reference

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7 July 2018

Staging of non-small cell lung cancer: consensus, controversies and challenges

1 reference

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Simultaneous quantification of S-adenosyl methionine and S-adenosyl homocysteine in human plasma by stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry

1 reference

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21 January 2018

Direct and tumor microenvironment mediated influences of 5'-deoxy-5'-(methylthio)adenosine on tumor progression of malignant melanoma

1 reference

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1 reference

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21 January 2018

Identification and validation of a potent type II inhibitor of inactive polo-like kinase 1.

1 reference

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21 January 2018

Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis.

1 reference

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21 January 2018

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1 reference

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27 October 2018

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1 reference

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12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21135097

12 December 2020

based on heuristic

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Identifiers

10.1074/JBC.M110.198374

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21135097%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

Europe PubMed Central

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17 January 2020

1 reference

Europe PubMed Central

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17 January 2020

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