(Q34580424)

3 August 2017

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title

Peroxisome proliferator-activated receptor gamma agonists: potential use for treating chronic inflammatory diseases (English)

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3 August 2017

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4

Gary S Gilkeson

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3 August 2017

James C Oates

1

1 reference

PubMed ID

11920394

3 August 2017

Christopher M Reilly

series ordinal

2

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PubMed ID

11920394

3 August 2017

Michelle B Crosby

series ordinal

3

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3 August 2017

1 March 2002

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3 August 2017

Arthritis & Rheumatology

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3 August 2017

46

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3 August 2017

3

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3 August 2017

598-605

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Peroxisome proliferator-activated receptor gamma1 (PPARgamma1) expresses in rat mesangial cells and PPARgamma agonists modulate its differentiation

3 August 2017

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Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages

21 January 2018

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15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats

21 January 2018

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15-Deoxy-delta12,14-PGJ2, but not troglitazone, modulates IL-1beta effects in human chondrocytes by inhibiting NF-kappaB and AP-1 activation pathways.

21 January 2018

1 reference

An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer

21 January 2018

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Peroxisome proliterator-activated receptors, orphans with ligands and functions

21 January 2018

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PPARgamma3 mRNA: a distinct PPARgamma mRNA subtype transcribed from an independent promoter

21 January 2018

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Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

21 January 2018

1 reference

Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators

21 January 2018

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Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma

21 January 2018

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Inhibition of adipogenesis by a COOH-terminally truncated mutant of PPARgamma2 in 3T3-L1 cells

21 January 2018

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A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding

21 January 2018

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Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription

21 January 2018

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

Induction of the acyl-coenzyme A synthetase gene by fibrates and fatty acids is mediated by a peroxisome proliferator response element in the C promoter

21 January 2018

1 reference

PPARgamma induces the insulin-dependent glucose transporter GLUT4 in the absence of C/EBPalpha during the conversion of 3T3 fibroblasts into adipocytes

21 January 2018

1 reference

Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene

21 January 2018

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Hypertension and insulin resistance: role of peroxisome proliferator-activated receptor gamma.

21 January 2018

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Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes

21 January 2018

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

21 January 2018

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Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

21 January 2018

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Molecular cloning and characterization of the rat inducible nitric oxide synthase (iNOS) gene.

21 January 2018

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Cytokine-mediated transcriptional induction of the human inducible nitric oxide synthase gene requires both activator protein 1 and nuclear factor kappaB-binding sites

21 January 2018

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Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene

21 January 2018

1 reference

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

21 January 2018

1 reference

Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs

21 January 2018

1 reference

Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2

21 January 2018

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15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

21 January 2018

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PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

21 January 2018

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The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

21 January 2018

1 reference

The PPARs: from orphan receptors to drug discovery

21 January 2018

1 reference

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

21 January 2018

1 reference

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

21 January 2018

1 reference

Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein

21 January 2018

1 reference

Transforming growth factor-beta1 (TGF-beta1) and TGF-beta2 decrease expression of CD36, the type B scavenger receptor, through mitogen-activated protein kinase phosphorylation of peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

Prostaglandin J(2) inhibition of mesangial cell iNOS expression

21 January 2018

1 reference

Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages

21 January 2018

1 reference

Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis

21 January 2018

1 reference

Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis

21 January 2018

1 reference

Activation of PPARalpha or gamma reduces secretion of matrix metalloproteinase 9 but not interleukin 8 from human monocytic THP-1 cells.

21 January 2018

1 reference

Anti-inflammatory actions of 15-deoxy-delta 12,14-prostaglandin J2 and troglitazone: evidence for heat shock-dependent and -independent inhibition of cytokine-induced inducible nitric oxide synthase expression

21 January 2018

1 reference

Activation of peroxisome proliferator-activated receptor gamma does not inhibit IL-6 or TNF-alpha responses of macrophages to lipopolysaccharide in vitro or in vivo

21 January 2018

1 reference

Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT.

21 January 2018

1 reference

Peroxisome proliferator-activated receptor gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300.

21 January 2018

1 reference

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

21 January 2018

1 reference

New oral therapies for type 2 diabetes mellitus: The glitazones or insulin sensitizers

21 January 2018

1 reference

Troglitazone improves psoriasis and normalizes models of proliferative skin disease: ligands for peroxisome proliferator-activated receptor-gamma inhibit keratinocyte proliferation

21 January 2018

1 reference

The organization, promoter analysis, and expression of the human PPARgamma gene

21 January 2018

1 reference

A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response

21 January 2018

1 reference

Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice

21 January 2018

1 reference

Peroxisome proliferator-activated receptor-gamma: a versatile metabolic regulator

21 January 2018

1 reference

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

21 January 2018

1 reference

Medical significance of peroxisome proliferator-activated receptors.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/ART.10052

1 reference

3 August 2017

1 reference

PubMed ID

11920394