(Q34583598)

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Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

natural product

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based on heuristic

inferred from title

Christian A. Olsen

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

W Seth Horne

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

John M Beierle

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Ana Montero

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

M Reza Ghadiri

5

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22 January 2020

language of work or name

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1 January 2009

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Europe PubMed Central

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22 January 2020

Angewandte Chemie International Edition

1 reference

Europe PubMed Central

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22 January 2020

48

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

26

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

4718-4724

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Histone deacetylase inhibitors through click chemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Ruthenium-catalyzed azide-alkyne cycloaddition: scope and mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Isoform-selective histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Peptidomimetics via copper-catalyzed azide-alkyne cycloadditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Ruthenium-catalyzed cycloaddition of alkynes and organic azides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Efficient route to C2 symmetric heterocyclic backbone modified cyclic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Epigenetics--an epicenter of gene regulation: histones and histone-modifying enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Heterocyclic peptide backbone modifications in an alpha-helical coiled coil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Polytriazoles as copper(I)-stabilizing ligands in catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Histone deacetylases (HDACs): characterization of the classical HDAC family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Histone deacetylase: a target for antiproliferative and antiprotozoal agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Multiple interconverting conformers of the cyclic tetrapeptide tentoxin, [cyclo-(L-MeAla1-L-Leu2-MePhe[(Z) delta]3-Gly4)], as seen by two-dimensional 1H-nmr spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

On the dependence of molecular conformation on the type of solvent environment: a molecular dynamics study of cyclosporin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Isotope-edited NMR of cyclosporin A bound to cyclophilin: evidence for a trans 9,10 amide bond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

7 July 2018

The 1,2,3-triazole ring as a peptido- and olefinomimetic element: discovery of click vanilloids and cannabinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Click chemistry as a macrocyclization tool in the solid-phase synthesis of small cyclic peptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Molecular design of histone deacetylase inhibitors by aromatic ring shifting in chlamydocin framework.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Translating peptides into small molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Engineering cyclic tetrapeptides containing chimeric amino acids as preferred reverse-turn scaffolds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Solution, solid phase and computational structures of apicidin and its backbone-reduced analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Nonpeptidic foldamers from amino acids: synthesis and characterization of 1,3-substituted triazole oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Conformational analysis of drug-like molecules bound to proteins: an extensive study of ligand reorganization upon binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

A heterocyclic peptide nanotube

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Predicting the conformational states of cyclic tetrapeptides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

A cis amide bond surrogate incorporating 1,2,4-triazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3041267

27 October 2018

1,2,3-Triazoles as peptide bond isosteres: synthesis and biological evaluation of cyclotetrapeptide mimics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational polymorphism in peptidic and nonpeptidic drug molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction of a triazole amino acid into a peptoid oligomer induces turn formation in aqueous solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrazoles, 1,2,4-triazoles, and tetrazoles as surrogates for cis-amide bonds in boronate ester thrombin inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improving Oral Bioavailability of Peptides by Multiple N-Methylation: Somatostatin Analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ring closure to beta-turn mimics via copper-catalyzed azide/alkyne cycloadditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Empirical rules predicting conformation of cyclic tetrapeptides from primary structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Click chemistry as a route to cyclic tetrapeptide analogues: synthesis of cyclo-[Pro-Val-psi(triazole)-Pro-Tyr]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Semisynthesis of an analogue of antitumor bicyclic hexapeptide RA-VII by fixing the Ala-2/Tyr-3 bond to Cis by incorporating a triazole cis-amide bond surrogate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ruthenium-catalyzed cycloaddition of aryl azides and alkynes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19267380

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/ANIE.200805900

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19267380%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

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