(Q34584573)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

9 January 2020

main subject

phase III clinical trial

0 references

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

10

Hiroshi Mitsumoto

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

17

Michael C Graves

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

18

Leo F McCluskey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Dan H Moore

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Robert G Miller

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Julaine M Florence

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Joseph L Verheijde

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Carolyn Doorish

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Joan F Hilton

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

G Mark Spitalny

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Robert B MacArthur

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Hans E Neville

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Kevin Boylan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Tahseen Mozaffar

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Jerry M Belsh

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

John Ravits

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Richard S Bedlack

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Richard J Barohn

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Rup Tandan

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Western ALS Study Group

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

publication date

5 November 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

page(s)

1045-1053

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17980667%20AND%20SRC:MED&resulttype=core&format=json

Amyotrophic lateral sclerosis

9 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Clinical pharmacokinetics of doxycycline and minocycline

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline delays disease onset and mortality in a transgenic model of ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline in amyotrophic lateral sclerosis: a pilot study

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Prognostic indicators of survival in ALS. ALS CNTF Treatment Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Performance of the Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) in multicenter clinical trials.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III).

1 reference

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7 January 2021

A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Phase III randomized trial of gabapentin in patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

A comparison of muscle strength testing techniques in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Quality of life in ALS is maintained as physical function declines

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Phase II/III randomized trial of TCH346 in patients with ALS

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Pentoxifylline in ALS: a double-blind, randomized, multicenter, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline safety and tolerability in Huntington disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline enhances MPTP toxicity to dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline worsens hypoxic-ischemic brain injury in a neonatal mouse model.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Neuroprotective and anti-human immunodeficiency virus activity of minocycline

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline prevents cholinergic loss in a mouse model of Down's syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Minocycline affects microglia activation, Abeta deposition, and behavior in APP-tg mice

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Inhibition of autoimmune encephalomyelitis by a tetracycline.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2807%2970270-3

7 January 2021

Effective combination of minocycline and interferon-beta in a model of multiple sclerosis

1 reference

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7 January 2021

Lost in translation: treatment trials in the SOD1 mouse and in human ALS.

1 reference

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7 January 2021

Guidelines for the preclinical in vivo evaluation of pharmacological active drugs for ALS/MND: report on the 142nd ENMC international workshop.

1 reference

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7 January 2021

An efficient multi‐stage, single‐arm Phase II futility design for ALS

1 reference

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7 January 2021

Selecting promising ALS therapies in clinical trials.

1 reference

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7 January 2021

Use of Sniff nasal-inspiratory force to predict survival in amyotrophic lateral sclerosis.

1 reference

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7 January 2021