(Q34587432)

3 August 2017

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title

Balancing immunity and pathology in visceral leishmaniasis (English)

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3 August 2017

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visceral leishmaniasis

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inferred from title

author

Christian R. Engwerda

object named as

Christian R Engwerda

series ordinal

2

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author name string

Amanda C Stanley

series ordinal

1

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3 August 2017

5 December 2006

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Immunology & Cell Biology

3 August 2017

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3 August 2017

85

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3 August 2017

2

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3 August 2017

138-147

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Tropical medicine for the 21st century. Tropical medicine should be concerned with medical problems endemic to the tropics

3 August 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Leishmaniasis in Sudan. Visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Leishmaniasis: new approaches to disease control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Drug resistance in leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Post-kala-azar dermal leishmaniasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Recent developments in leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Impact of highly active antiretroviral therapy on the incidence of visceral leishmaniasis in a French cohort of patients infected with human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Incidence of and risk factors for symptomatic visceral leishmaniasis among human immunodeficiency virus type 1-infected patients from Spain in the era of highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Intradermal infection model for pathogenesis and vaccine studies of murine visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

SLC11A1 (formerly NRAMP1) and disease resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Natural resistance to infection with intracellular pathogens: the Nramp1 protein is recruited to the membrane of the phagosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Role of Lsh in regulating macrophage priming/activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Slc11a1-mediated resistance to Salmonella enterica serovar Typhimurium and Leishmania donovani infections does not require functional inducible nitric oxide synthase or phagocyte oxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

The macrophage resistance gene Lsh/Ity/Bcg

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

SLC11A1 (formerly NRAMP1) and susceptibility to visceral leishmaniasis in The Sudan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Leishmania donovani-induced expression of suppressor of cytokine signaling 3 in human macrophages: a novel mechanism for intracellular parasite suppression of activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Activation of TGF-beta by Leishmania chagasi: importance for parasite survival in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Leishmania donovani suppresses activated protein 1 and NF-kappaB activation in host macrophages via ceramide generation: involvement of extracellular signal-regulated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Leishmania priming of human dendritic cells for CD40 ligand-induced interleukin-12p70 secretion is strain and species dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Kinetics of gamma interferon binding and induction of major histocompatibility complex class II mRNA in Leishmania-infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Deficient expression of co-stimulatory molecules on Leishmania-infected macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Unresponsive CD4+ T lymphocytes from Leishmania chagasi-infected mice increase cytokine production and mediate parasite killing after blockade of B7-1/CTLA-4 molecular pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Organ-specific immune responses associated with infectious disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Leishmania donovani infection of a susceptible host results in CD4+ T-cell apoptosis and decreased Th1 cytokine production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

CD95 is required for the early control of parasite burden in the liver of Leishmania donovani-infected mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

The dynamics of granuloma formation in experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Liver morphology and function in visceral leishmaniasis (Kala-azar)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Tissue granuloma structure-function in experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Visceral leishmaniasis in mice devoid of tumor necrosis factor and response to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Distinct roles for lymphotoxin-alpha and tumor necrosis factor in the control of Leishmania donovani infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Leishmania donovani infection initiates T cell-independent chemokine responses, which are subsequently amplified in a T cell-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

B cell-deficient mice are highly resistant to Leishmania donovani infection, but develop neutrophil-mediated tissue pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Invariant NKT cells are essential for the regulation of hepatic CXCL10 gene expression during Leishmania donovani infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

The immunopathology of experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Modulation of T-Cell Costimulation as Immunotherapy or Immunochemotherapy in Experimental Visceral Leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Immunotherapy with OX40L-Fc or anti-CTLA-4 enhances local tissue responses and killing of Leishmania donovani.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Effect of granulocyte-macrophage colony-stimulating factor in experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Intracellular antimicrobial activity in the absence of interferon-gamma: effect of interleukin-12 in experimental visceral leishmaniasis in interferon-gamma gene-disrupted mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Therapeutic effect of interferon-gamma gene transfer in experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Reduced nitric oxide synthase 2 (NOS2) promoter activity in the Syrian hamster renders the animal functionally deficient in NOS2 activity and unable to control an intracellular pathogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

An in vivo analysis of cytokine production during Leishmania donovani infection in scid mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

IL-10 mediates susceptibility to Leishmania donovani infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Determinants of response to interleukin-10 receptor blockade immunotherapy in experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Interleukin 10 production correlates with pathology in human Leishmania donovani infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Macrophage deactivation by interleukin 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Antagonizing deactivating cytokines to enhance host defense and chemotherapy in experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Cells in the marginal zone of the spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Structure and function of the spleen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Loss of dendritic cell migration and impaired resistance to Leishmania donovani infection in mice deficient in CCL19 and CCL21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Myd88-dependent in vivo maturation of splenic dendritic cells induced by Leishmania donovani and other Leishmania species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

RNA interference reveals a role for TLR2 and TLR3 in the recognition of Leishmania donovani promastigotes by interferon-gamma-primed macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Interleukin 12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Inhibition of CD1 expression in human dendritic cells during intracellular infection with Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

The TGF-beta response to Leishmania chagasi in the absence of IL-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Chemokines: a new classification system and their role in immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Localization of marginal zone macrophages is regulated by C-C chemokine ligands 21/19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Enhanced hematopoietic activity accompanies parasite expansion in the spleen and bone marrow of mice infected with Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Stromal cells direct local differentiation of regulatory dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

American cutaneous leishmaniasis unresponsive to antimonial drugs: successful treatment using combination of N-methilglucamine antimoniate plus pentoxifylline

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

Presence of Leishmania organisms in specific and non-specific skin lesions in HIV-infected individuals with visceral leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Expression of the natural resistance gene Lsh in resident liver macrophages.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Leishmania donovani infection in heterozygous and recombinant H-2 haplotype mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Dendritic cells, but not macrophages, produce IL-12 immediately followingLeishmania donovani infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Immunology of leishmaniasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Antimicrobial response of a T cell-deficient host to cytokine therapy: effect of interferon-gamma in experimental visceral leishmaniasis in nude mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Hepatic fibrin-ring granulomas in visceral leishmaniasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

TGF-beta mediates CTLA-4 suppression of cellular immunity in murine kalaazar

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Endogenous interleukin-12 regulates acquired resistance in experimental visceral leishmaniasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Cutting Edge: STAT1 and T-bet Play Distinct Roles in Determining Outcome of Visceral Leishmaniasis Caused by Leishmania donovani

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Responses to Leishmania donovani in mice deficient in both phagocyte oxidase and inducible nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Immature human dendritic cells infected with Leishmania infantum are resistant to NK-mediated cytolysis but are efficiently recognized by NKT cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

A murine transmembrane tumor necrosis factor (TNF) transgene induces arthritis by cooperative p55/p75 TNF receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Differences in Lsh gene control over systemic Leishmania major and Leishmania donovani or Leishmania mexicana mexicana infections are caused by differential targeting to infiltrating and resident liver macrophage populations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

The Anaemia of Kala Azar

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ICB7100011

7 January 2021

Identifiers

DOI

10.1038/SJ.ICB7100011

1 reference

3 August 2017

1 reference

PubMed ID

17146466