(Q34596110)

3 August 2017

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title

Complex roles of tissue inhibitors of metalloproteinases in cancer (English)

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3 August 2017

Yangfu Jiang

1

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3 August 2017

Itzhak D Goldberg

series ordinal

2

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3 August 2017

Y Eric Shi

series ordinal

3

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3 August 2017

language of work or name

English

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publication date

1 March 2002

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3 August 2017

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3 August 2017

21

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3 August 2017

2245-2252

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3 August 2017

14

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205291

3 August 2017

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cites work

Tumor Cell Invasion Inhibited by TIMP-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2(Timp-2) gene alters proMMP-2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Matrix metalloproteinases and the development of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inhibition of endothelial cell migration by gene transfer of tissue inhibitor of metalloproteinases-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Tissue inhibitor of metalloproteinase-1 alters the tumorigenicity of Burkitt's lymphoma via divergent effects on tumor growth and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Cloning and partial structure of the gene encoding human tissue inhibitor of metalloproteinases-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Differential roles of TIMP-4 and TIMP-2 in pro-MMP-2 activation by MT1-MMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Increased expression of tissue inhibitor of metalloproteinases type 1 (TIMP-1) in a more tumourigenic colon cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Tissue inhibitor of metalloproteinases-2 (TIMP-2) suppresses TKR-growth factor signaling independent of metalloproteinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Dormancy of mammary carcinoma after mastectomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Synthetic inhibitor of matrix metalloproteinases (batimastat) reduces prostate cancer growth in an orthotopic rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

ECM signalling: orchestrating cell behaviour and misbehaviour.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Tissue inhibitor of metalloprotease (TIMP)-1 and proliferative behaviour of clonal breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Expression and Prognostic Significance of Metalloproteinases and Their Tissue Inhibitors in Patients With Small-Cell Lung Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

TIMP-3 mRNA expression is regionally increased in moderately and poorly differentiated colorectal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Tissue inhibitor of metalloproteinases-1 (TIMP-1) binds to the cell surface and translocates to the nucleus of human MCF-7 breast carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Matrix metalloproteinases in remodeling of the normal and neoplastic mammary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Role of tissue inhibitor of metalloproteinases-2 (TIMP-2) in regulation of pro-gelatinase A activation catalyzed by membrane-type matrix metalloproteinase-1 (MT1-MMP) in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Marimastat: the clinical development of a matrix metalloproteinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Localization and quantification of mRNA for matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix metalloproteinase-2 (TIMP-2) in human benign and malignant prostatic tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Cancer dormancy: opportunities for new therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Inhibition of metastasis in human gastric cancer cells transfected with tissue inhibitor of metalloproteinase 1 gene in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Enhanced RNA expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Mammary carcinoma cells over-expressing tissue inhibitor of metalloproteinases-1 show enhanced vascular endothelial growth factor expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Prognostic value of tissue inhibitor of matrix metalloproteinase-1 in plasma of patients with gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Localization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus. Metalloproteinase inhibition is associated with proapoptotic activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Human tissue inhibitor of metalloproteinases 3 interacts with both the N- and C-terminal domains of gelatinases A and B. Regulation by polyanions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

The propeptide domain of membrane type 1 matrix metalloproteinase is required for binding of tissue inhibitor of metalloproteinases and for activation of pro-gelatinase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma--a clinicopathologic study using immunohistochemistry and mRNA in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

MMPI demise spotlights target choice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Plasma membrane-bound tissue inhibitor of metalloproteinases (TIMP)-2 specifically inhibits matrix metalloproteinase 2 (gelatinase A) activated on the cell surface

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Expression of tissue inhibitors of metalloproteinases (TIMPs) in gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Suppression of the tumorigenic and metastatic abilities of murine B16-F10 melanoma cells in vivo by the overexpression of the tissue inhibitor of the metalloproteinases-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Metalloproteinases and Tissue Inhibitors of Matrix-Metalloproteinases in Plasma of Patients with Prostate Cancer and in Prostate Cancer Tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Transfection of an invasive human astrocytoma cell line with a TIMP-1 cDNA: modulation of astrocytoma invasive potential.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

High levels of tissue inhibitor of metalloproteinase-1 predict poor outcome in patients with breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Regulation of angiostatin production by matrix metalloproteinase-2 in a model of concomitant resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Angiostatin-converting enzyme activities of human matrilysin (MMP-7) and gelatinase B/type IV collagenase (MMP-9)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 expression in human amnion mesenchymal and epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Tissue inhibitor of metalloproteinase-2 (TIMP-2) has erythroid-potentiating activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Matrix metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205291

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205291

1 reference

Dimensions Publication ID

3 August 2017

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1 reference