(Q34599780)

3 August 2017

1 reference

title

The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review (English)

1 reference

3 August 2017

Klok MD

1

1 reference

PubMed ID

17212793

3 August 2017

Jakobsdottir S

series ordinal

2

1 reference

PubMed ID

17212793

3 August 2017

Drent ML

series ordinal

3

1 reference

3 August 2017

1 January 2007

1 reference

3 August 2017

1 reference

3 August 2017

8

1 reference

3 August 2017

1

1 reference

3 August 2017

21-34

1 reference

Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002.

3 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Obesity: epidemiology and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Neuroendocrine effects of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin signaling in the hypothalamus: emphasis on energy homeostasis and leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Structural organization and chromosomal assignment of the human obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Genomic structure and promoter analysis of the human obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Presence of leptin in colostrum and/or breast milk from lactating mothers: a potential role in the regulation of neonatal food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

The stomach is a source of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin secretion and leptin receptor in the human stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin expression in placental and fetal tissues: does leptin have a functional role?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

The long form of the leptin receptor (OB-Rb) is widely expressed in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin-induced signal transduction pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Expression of placental leptin and leptin receptor transcripts in early pregnancy and at term

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Biological action of leptin as an angiogenic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Effect of Fasting, Refeeding, and Dietary Fat Restriction on Plasma Leptin Levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Resting metabolic rate in healthy adults: relation to growth hormone status and leptin levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Partial leptin deficiency and human adiposity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Intact sympathetic nervous system is required for leptin effects on resting metabolic rate in people with spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Response of leptin to short-term and prolonged overfeeding in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin levels do not change acutely with food administration in normal or obese subjects, but are negatively correlated with pituitary-adrenal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

The metabolic significance of leptin in humans: gender-based differences in relationship to adiposity, insulin sensitivity, and energy expenditure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin gene expression and systemic levels in healthy men: effect of exercise, carbohydrate, interleukin-6, and epinephrine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin regulates bone formation via the sympathetic nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Pathophysiological significance of the obese gene product, leptin, in ventromedial hypothalamus (VMH)-lesioned rats: evidence for loss of its satiety effect in VMH-lesioned rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Effects of leptin and corticosterone on the expression of corticotropin-releasing hormone, agouti-related protein, and proopiomelanocortin in the brain of ob/ob mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin regulation of prepro-orexin and orexin receptor mRNA levels in the hypothalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Changes in Hypothalamic Expression Levels of Galanin-Like Peptide in Rat and Mouse Models Support That It Is a Leptin-Target Peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

A role for ghrelin in the central regulation of feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Hypothalamic CART is a new anorectic peptide regulated by leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Brain-derived neurotrophic factor plays a role as an anorexigenic factor in the dorsal vagal complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Relationship between circulating leptin and energy expenditure in adult men and women aged 18 years to 81 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin, gut, and food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Vagal stimulation rapidly increases leptin secretion in human stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Role of leptin in energy-deprivation states: normal human physiology and clinical implications for hypothalamic amenorrhoea and anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin: a gastric peptide that regulates food intake and energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Immunolocalization of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in the cyclic human ovary

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Presence of ghrelin in normal and adenomatous human pituitary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

A receptor in pituitary and hypothalamus that functions in growth hormone release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Genomic structure and transcriptional regulation of the human growth hormone secretagogue receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Expression of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in normal human testis and testicular tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Post-prandial decrease of circulating human ghrelin levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Plasma ghrelin concentrations in elderly subjects: comparison with anorexic and obese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin secretion in humans is sexually dimorphic, suppressed by somatostatin, and not affected by the ambient growth hormone levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Neurosteroid metabolism in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Weight loss increases circulating levels of ghrelin in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin--a hormone with multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: responses to the intravenous and oral administration of glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Deletion of Ghrelin Impairs neither Growth nor Appetite

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin acts in the central nervous system to stimulate gastric acid secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin induces adiposity in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and food-related cues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin enhances appetite and increases food intake in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Neuroendocrine and Metabolic Effects of Acute Ghrelin Administration in Human Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin stimulates appetite, imagination of food, GH, ACTH, and cortisol, but does not affect leptin in normal controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Correlation between fasting plasma ghrelin levels and age, body mass index (BMI), BMI percentiles, and 24-hour plasma ghrelin profiles in Prader-Willi syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Energy homeostasis and gastric emptying in ghrelin knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Overexpression of the obese (ob) gene in adipose tissue of human obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

A leptin missense mutation associated with hypogonadism and morbid obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Obese (ob) gene defects are rare in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Human leptin receptor gene in obese Japanese subjects: evidence against either obesity-causing mutations or association of sequence variants with obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Large-scale studies of the Leu72Met polymorphism of the ghrelin gene in relation to the metabolic syndrome and associated quantitative traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin receptor gene: identification of several sequence variants in extremely obese children and adolescents, healthy normal-weight and underweight students, and children with short normal stature

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Weekly subcutaneous pegylated recombinant native human leptin (PEG-OB) administration in obese men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Resistance to the satiety action of leptin following chronic central leptin infusion is associated with the development of leptin resistance in neuropeptide Y neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

The role of agouti-related protein in regulating body weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Identification of SOCS-3 as a potential mediator of central leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Physiological studies of transgenic mice overexpressing growth hormone (GH) secretagogue receptor 1A in GH-releasing hormone neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Engineering a pharmacologically superior form of leptin for the treatment of obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Anti-ghrelin Spiegelmer NOX-B11 inhibits neurostimulatory and orexigenic effects of peripheral ghrelin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Constitutive ghrelin receptor activity as a signaling set-point in appetite regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Antagonism of ghrelin receptor reduces food intake and body weight gain in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

A novel growth hormone secretagogue-1a receptor antagonist that blocks ghrelin-induced growth hormone secretion but induces increased body weight gain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

PTP1B regulates leptin signal transduction in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Endocrine responses to the oral ingestion of a physiological dose of essential amino acids in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Differential Responses of Circulating Ghrelin to High-Fat or High-Carbohydrate Meal in Healthy Women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Differential effect of protein and fat on plasma ghrelin levels in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Ghrelin secretion is modulated in a nutrient- and gender-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Loss of meal-induced decrease in plasma ghrelin levels in patients with anorexia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

Generation of a Phenotypic Array of Hypothalamic Neuronal Cell Models to Study Complex Neuroendocrine Disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2006.00270.X

10.1111/J.1467-789X.2006.00270.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

17212793