(Q34612062)

3 August 2017

title

Modulation of aflatoxin B1-mediated genotoxicity in primary cultures of human hepatocytes by diindolylmethane, curcumin, and xanthohumols (English)

1 reference

3 August 2017

0 references

1 reference

Stephen C Strom

5

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author name string

Kerstin Gross-Steinmeyer

1

1 reference

3 August 2017

Patricia L Stapleton

2

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3 August 2017

Julia H Tracy

3

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3 August 2017

Theo K Bammler

4

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3 August 2017

Donald R Buhler

6

1 reference

3 August 2017

David L Eaton

7

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3 August 2017

publication date

21 September 2009

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3 August 2017

published in

Toxicological Sciences

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3 August 2017

volume

112

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3 August 2017

issue

2

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3 August 2017

page(s)

303-310

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Single-dose pharmacokinetics and tolerability of absorption-enhanced 3,3'-diindolylmethane in healthy subjects

3 August 2017

cites work

1 reference

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7 July 2018

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Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis

7 July 2018

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Biological effects of curcumin and its role in cancer chemoprevention and therapy

7 July 2018

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7 July 2018

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Chemopreventive functions of isothiocyanates

7 July 2018

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Sequence diversity and haplotype structure at the human CYP3A cluster

7 July 2018

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Polymorphism of glutathione S-transferase mu 1 and theta 1 genes and hepatocellular carcinoma in southern Guangxi, China

7 July 2018

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Complementary DNA cloning, protein expression, and characterization of alpha-class GSTs from Macaca fascicularis liver

7 July 2018

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Interindividual differences in response to chemoprotection against aflatoxin-induced hepatocarcinogenesis: implications for human biotransformation enzyme polymorphisms.

7 July 2018

1 reference

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Role of phase 2 enzyme induction in chemoprotection by dithiolethiones

7 July 2018

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Signal transduction events elicited by cancer prevention compounds

7 July 2018

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Chemoprotection by organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins

7 July 2018

1 reference

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The micronutrient indole-3-carbinol: implications for disease and chemoprevention

7 July 2018

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Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets

7 July 2018

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Progress in cancer chemoprevention: development of diet-derived chemopreventive agents

7 July 2018

1 reference

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Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Dietary effect on mixed function P450 1A2 activity assayed by estimation of caffeine metabolism in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Mechanisms of aflatoxin carcinogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Comparison of the aflatoxin B1-8,9-epoxide conjugating activities of two bacterially expressed alpha class glutathione S-transferase isozymes from mouse and rat

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Dominant contribution of P450 3A4 to the hepatic carcinogenic activation of aflatoxin B1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Influence of Matrigel-overlay on constitutive and inducible expression of nine genes encoding drug-metabolizing enzymes in primary human hepatocytes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Hepatocellular carcinoma and polymorphisms in carcinogen-metabolizing and DNA repair enzymes in a population with aflatoxin exposure and hepatitis B virus endemicity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Phytochemical-induced changes in gene expression of carcinogen-metabolizing enzymes in cultured human primary hepatocytes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Modulations of P450 mRNA in liver and mammary gland and P450 activities and metabolism of estrogen in liver by treatment of rats with indole-3-carbinol

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae reveals a functional role in aflatoxin B1 detoxification.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Simultaneous characterization of glutathione S-transferase M1 and T1 polymorphisms by polymerase chain reaction in American whites and blacks.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

Procarcinogen activation by cytochrome P450 3A4 and 3A5 expressed in Escherichia coli and by human liver microsomes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2777076

The polymorphisms of GSTM1, GSTT1, HYL1*2, and XRCC1, and aflatoxin B1-related hepatocellular carcinoma in Guangxi population, China

26 October 2018

1 reference

12 December 2020

Content of glucosinolates in cruciferous vegetables grown at the same site for two years under different climatic conditions

1 reference

12 December 2020

Single-dose and multiple-dose administration of indole-3-carbinol to women: pharmacokinetics based on 3,3'-diindolylmethane

1 reference

12 December 2020

In vitro inhibition of human P450 enzymes by prenylated flavonoids from hops, Humulus lupulus

1 reference

12 December 2020

Use of human hepatocytes to study P450 gene induction

1 reference

12 December 2020

Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro

1 reference

12 December 2020

Saccharomyces cerevisiae: an alternative source for human microsomal liver enzymes and its use in drug interaction studies

1 reference

12 December 2020

Promotion of aflatoxin B1 carcinogenesis by the natural tumor modulator indole-3-carbinol: influence of dose, duration, and intermittent exposure on indole-3-carbinol promotional potency

1 reference

12 December 2020

Fate of xanthohumol and related prenylflavonoids from hops to beer

1 reference

12 December 2020

Identifiers

DOI

10.1093/TOXSCI/KFP206

1 reference

3 August 2017

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3 August 2017

1 reference