(Q34614586)

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Entrapment via synaptic-like connections between NG2 proteoglycan+ cells and dystrophic axons in the lesion plays a role in regeneration failure after spinal cord injury

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Europe PubMed Central

PubMed publication ID

3 August 2017

Entrapment via synaptic-like connections between NG2 proteoglycan+ cells and dystrophic axons in the lesion plays a role in regeneration failure after spinal cord injury (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

Dwight E. Bergles

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25471575%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

11

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10 June 2020

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Angela R Filous

1

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10 June 2020

Amanda Tran

2

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10 June 2020

C James Howell

3

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10 June 2020

Sarah A Busch

4

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10 June 2020

Teresa A Evans

5

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10 June 2020

William B Stallcup

6

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10 June 2020

Shin H Kang

7

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10 June 2020

Seong-il Lee

9

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10 June 2020

Joel M Levine

10

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10 June 2020

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1 December 2014

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3 August 2017

Journal of Neuroscience

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10 June 2020

34

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10 June 2020

49

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10 June 2020

16369-16384

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10 June 2020

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11 June 2022

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AAVshRNA-mediated suppression of PTEN in adult rats in combination with salmon fibrin administration enables regenerative growth of corticospinal axons and enhances recovery of voluntary motor function after cervical spinal cord injury

1 reference

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7 July 2018

Perivascular fibroblasts form the fibrotic scar after contusive spinal cord injury

1 reference

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7 July 2018

LAR-RPTPs: synaptic adhesion molecules that shape synapse development

1 reference

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Myelin repair and functional recovery mediated by neural cell transplantation in a mouse model of multiple sclerosis

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7 July 2018

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

1 reference

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7 July 2018

Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors

1 reference

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7 July 2018

A pericyte origin of spinal cord scar tissue

1 reference

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7 July 2018

In vivo imaging of dorsal root regeneration: rapid immobilization and presynaptic differentiation at the CNS/PNS border

1 reference

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7 July 2018

Unexpected survival of neurons of origin of the pyramidal tract after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Adult NG2+ cells are permissive to neurite outgrowth and stabilize sensory axons during macrophage-induced axonal dieback after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Synapses on NG2-expressing progenitors in the brain: multiple functions?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

NG2 glial cells provide a favorable substrate for growing axons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

NG2: a component of the glial scar that inhibits axon growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Multiple regions of the NG2 proteoglycan inhibit neurite growth and induce growth cone collapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Chondroitinase ABC promotes functional recovery after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Structure and function of aggrecan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Versican is upregulated in CNS injury and is a product of oligodendrocyte lineage cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Survival and regeneration of rubrospinal neurons 1 year after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Embryonic neurons adapt to the inhibitory proteoglycan aggrecan by increasing integrin expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: the major axon-inhibitory proteoglycan is NG2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Glial cell extracellular matrix: boundaries for axon growth in development and regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Dynamic microtubule ends are required for growth cone turning to avoid an inhibitory guidance cue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Actin filament bundles are required for microtubule reorientation during growth cone turning to avoid an inhibitory guidance cue.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Expression of beta 1 integrins in sensory neurons of the dorsal root ganglion and their functions in neurite outgrowth on two laminin isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Axon Outgrowth Enhanced by a Previous Nerve Injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Regenerating axons form nerve terminals at astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

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Demonstration of the potential for chronically injured neurons to regenerate axons into intraspinal peripheral nerve grafts

1 reference

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A quantitative study of subsurface cisterns and their relationships in normal and axotomized hypoglossal neurones

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Axonal regeneration in the rat sciatic nerve: Effect of a conditioning lesion and of dbcAMP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

7 July 2018

Quantifying synapses: an immunocytochemistry-based assay to quantify synapse number

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Schwann cell chondroitin sulfate proteoglycan inhibits dorsal root ganglion neuron neurite outgrowth and substrate specificity via a soma and not a growth cone mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Stripe assay to examine axonal guidance and cell migration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Vesicular glutamate release from axons in white matter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Axon regeneration through scars and into sites of chronic spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Differential responses of spinal axons to transection: influence of the NG2 proteoglycan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Cell proliferation and replacement following contusive spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Axonal Regeneration through Regions of Chondroitin Sulfate Proteoglycan Deposition after Spinal Cord Injury: A Balance of Permissiveness and Inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

Chondroitin sulfate and cytoplasmic domain-dependent membrane targeting of the NG2 proteoglycan promotes retraction fiber formation and cell polarization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

26 October 2018

The role of proteoglycans in Schwann cell/astrocyte interactions and in regeneration failure at PNS/CNS interfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252548

9 December 2018

Studies on the development and behavior of the dystrophic growth cone, the hallmark of regeneration failure, in an in vitro model of the glial scar and after spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte-associated fibronectin is critical for axonal regeneration in adult white matter

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral injury enhances central regeneration of primary sensory neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes block axonal regeneration in mammals by activating the physiological stop pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A stable lead by modification of Sato's method

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved uranyl acetate staining for electron microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal axons in central nervous system scar tissue are closely related to laminin-immunoreactive astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth cones are actively influenced by substrate-bound adhesion molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NG2 colocalizes with axons and is expressed by a mixed cell population in spinal cord lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic Changes in NG2+ Cells after Spinal Cord Injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25471575

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1309-14.2014

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25471575%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25471575%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25471575%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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