(Q46345563)

English

NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors.

scientific article published in April 2002

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scholarly article

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8 December 2019

NG2 is a major chondroitin sulfate proteoglycan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11923444%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

oligodendrocyte

1 reference

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inferred from title

Mark H. Tuszynski

4

object named as

Mark H Tuszynski

1 reference

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8 December 2019

author name string

Leonard L Jones

1

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8 December 2019

Yu Yamaguchi

2

1 reference

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8 December 2019

William B Stallcup

3

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8 December 2019

language of work or name

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publication date

1 April 2002

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8 December 2019

Journal of Neuroscience

1 reference

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8 December 2019

22

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8 December 2019

2792-2803

1 reference

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8 December 2019

7

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8 December 2019

Glial cell extracellular matrix: boundaries for axon growth in development and regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional involvement of sciatic nerve-derived versican- and decorin-like molecules and other chondroitin sulphate proteoglycans in ECM-mediated cell adhesion and neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chondroitin sulfate and cytoplasmic domain-dependent membrane targeting of the NG2 proteoglycan promotes retraction fiber formation and cell polarization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory proteoglycan immunoreactivity is higher at the caudal than the rostral Schwann cell graft-transected spinal cord interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Normal and reactive NG2+ glial cells are distinct from resting and activated microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial fibrillary acidic protein (GFAP): purification from human fibrillary astrocytoma, development and validation of a radioimmunoassay for GFAP-like immunoactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glial scar and central nervous system repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basal membrane-depleted scar in lesioned CNS: characteristics and relationships with regenerating axons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia: a sensor for pathological events in the CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the NG2 chondroitin sulfate proteoglycan with type VI collagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical characterization of reactive optic nerve astrocytes and meningeal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell-adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-surface Molecules That Characterize Different Stages in the Development of Cerebellar Interneurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

cDNA cloning and the identification of an aggrecanase-like cleavage site in rat brevican.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: the major axon-inhibitory proteoglycan is NG2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of the oligodendrocyte progenitor cell population (defined by NG2 labelling) to demyelination of the adult spinal cord.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic factors, cellular bridges and gene therapy for spinal cord injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin-associated glycoprotein: a role in myelination and in the inhibition of axonal regeneration?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-affinity binding of basic fibroblast growth factor and platelet-derived growth factor-AA to the core protein of the NG2 proteoglycan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The membrane-spanning proteoglycan NG2 binds to collagens V and VI through the central nonglobular domain of its core protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type protein tyrosine phosphatase, with neurons, glia, and neural cell adhesion molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult neuronal regeneration induced by transgenic integrin expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silver staining of proteins in polyacrylamide gels

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of rubrospinal and corticospinal neurons to injury and neurotrophins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The primary structure of NG2, a novel membrane-spanning proteoglycan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Entorhinal cortex lesion in adult rats induces the expression of the neuronal chondroitin sulfate proteoglycan neurocan in reactive astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The brain chondroitin sulfate proteoglycan brevican associates with astrocytes ensheathing cerebellar glomeruli and inhibits neurite outgrowth from granule neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nogo-A, a potent inhibitor of neurite outgrowth and regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of brevican, a novel brain proteoglycan of the aggrecan/versican family.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral nerve injury fails to induce growth of lesioned ascending dorsal column axons into spinal cord scar tissue expressing the axon repellent Semaphorin3A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chondroitin sulphate proteoglycan brevican is upregulated by astrocytes after entorhinal cortex lesions in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and proliferation of endogenous oligodendrocyte precursor cells during ethidium bromide-induced demyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia-specific localisation of a novel calcium binding protein, Iba1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chondroitin sulfate proteoglycans neurocan and phosphacan are expressed by reactive astrocytes in the chronic CNS glial scar

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chondroitin sulfate proteoglycans in the developing central nervous system. II. Immunocytochemical localization of neurocan and phosphacan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of truncated forms of the NG2 proteoglycan by cell surface proteolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between putative inhibitory molecules at the dorsal root entry zone and failure of dorsal root axonal regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo proliferation of oligodendrocyte progenitors expressing PDGFalphaR during early remyelination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactions of oligodendrocyte precursor cells to alpha herpesvirus infection of the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of the alpha platelet-derived growth factor receptor from rat olfactory epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A diverse set of developmentally regulated proteoglycans is expressed in the rat central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain derived versican V2 is a potent inhibitor of axonal growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous corticospinal axonal plasticity and functional recovery after adult central nervous system injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor stimulates the accumulation of beta1 integrin at the tips of filopodia in the growth cones of sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NG2-expressing cells in the central nervous system: are they oligodendroglial progenitors?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on the pathology of several types of human spinal cord injury, with emphasis on the astrocyte response to penetrating injuries

1 reference

https://pubmed.ncbi.nlm.nih.gov/11923444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.22-07-02792.2002

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11923444%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11923444%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11923444%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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