(Q34615592)

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Cytotoxic Evaluation of 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone, 3-AP, in Peripheral Blood Lymphocytes of Patients with Refractory Solid Tumors using Electron Paramagnetic Resonance

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Europe PubMed Central

PubMed publication ID

3 August 2017

Cytotoxic Evaluation of 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone, 3-AP, in Peripheral Blood Lymphocytes of Patients with Refractory Solid Tumors using Electron Paramagnetic Resonance (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

10

object named as

George Wilding

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Europe PubMed Central

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3 August 2017

author name string

Jill M Kolesar

1

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Europe PubMed Central

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3 August 2017

Kamakshi Sachidanandam

2

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3 August 2017

William R Schelman

3

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Europe PubMed Central

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3 August 2017

Jens Eickhoff

4

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Europe PubMed Central

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3 August 2017

Kyle D Holen

5

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3 August 2017

Anne M Traynor

6

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Europe PubMed Central

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3 August 2017

Dona B Alberti

7

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3 August 2017

James P Thomas

8

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3 August 2017

Christopher R Chitambar

9

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3 August 2017

William E Antholine

11

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3 August 2017

publication date

1 January 2011

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3 August 2017

Experimental and Therapeutic Medicine

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3 August 2017

2

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3 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

119-123

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Europe PubMed Central

PubMed publication ID

3 August 2017

The maximum tolerated dose and biologic effects of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) in combination with irinotecan for patients with refractory solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Fluorescence properties and cellular distribution of the investigational anticancer drug triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone) and its zinc(II) complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Modulating radiation resistance by inhibiting ribonucleotide reductase in cancers with virally or mutationally silenced p53 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Inhibitory mechanisms of heterocyclic carboxaldehyde thiosemicabazones for two forms of human ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

A phase II trial of triapine (NSC# 663249) and gemcitabine as second line treatment of advanced non-small cell lung cancer: Eastern Cooperative Oncology Group Study 1503

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

A phase I study of Triapine in combination with doxorubicin in patients with advanced solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Electron paramagnetic resonance study of peripheral blood mononuclear cells from patients with refractory solid tumors treated with Triapine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone) induces apoptosis in ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Clinical and pharmacological studies with 5-hydroxy-2-formylpyridine thiosemicarbazone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Three-dimensional structure of the free radical protein of ribonucleotide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

7 July 2018

Examination of the antiproliferative activity of iron chelators: multiple cellular targets and the different mechanism of action of triapine compared with desferrioxamine and the potent pyridoxal isonicotinoyl hydrazone analogue 311.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

26 October 2018

Interaction of 2-formylpyridine thiosemicarbazonato copper (II) with ehrlich ascites tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046871

26 October 2018

Cytochrome c release from mitochondria: all or nothing

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of inhibition of ribonucleoside diphosphate reductase by a-(N)-heterocyclic aldehyde thiosemicarbazones

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the reaction of 2-formylpyridine thiosemicarbazone and its iron and copper complexes with biological systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of chelating agents upon the synthesis of nucleic acids and protein: Inhibition of DNA synthesis by 1-formylisoquinoline thiosemicarbazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of iron uptake in HL60 cells by 2-formylpyridine monothiosemicarbazonato Cu(II)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of 3-AP Triapine in patients with recurrent or metastatic head and neck squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship of intracellular iron chelation to the inhibition and regeneration of human ribonucleotide reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21373381

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3892/ETM.2010.165

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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