(Q34618241)

3 August 2017

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title

Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture (English)

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3 August 2017

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Ralf Bartenschlager

1

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author name string

Sandra Sparacio

series ordinal

2

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3 August 2017

10 April 2007

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3 August 2017

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3 August 2017

127

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3 August 2017

195-207

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3 August 2017

2

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Long-term transmission of defective RNA viruses in humans and Aedes mosquitoes

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Hepatitis C virus subgenomic replicons in the human embryonic kidney 293 cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Unexpected host range of hepatitis C virus replicons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Novel insights into hepatitis C virus replication and persistence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Replication of the hepatitis C virus in cell culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

An infectious molecular clone of a Japanese genotype 1b hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Hepatitis C Virus Entry Depends on Clathrin-Mediated Endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Efficient initiation of HCV RNA replication in cell culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell Culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

The hepatitis C virus alternate reading frame (ARF) and its family of novel products: the alternate reading frame protein/F-protein, the double-frameshift protein, and others

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon Activities

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Genotype 2a hepatitis C virus subgenomic replicon can replicate in HepG2 and IMY-N9 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Kissing-loop interaction in the 3' end of the hepatitis C virus genome essential for RNA replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Identification of a key determinant of hepatitis C virus cell culture adaptation in domain II of NS3 helicase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Replication Studies Using Genotype 1a Subgenomic Hepatitis C Virus Replicons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Effect of alpha interferon on the hepatitis C virus replicon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Molecular cloning and heterogeneity of the human hepatitis C virus (HCV) genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

An in vitro model of hepatitis C virion production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Generation of transmissible hepatitis C virions from a molecular clone in chimpanzees

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Diverse Effects of Cyclosporine on Hepatitis C Virus Strain Replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Generation of Infectious Hepatitis C Virus in Immortalized Human Hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Production of two phosphoproteins from the NS5A region of the hepatitis C viral genome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Nonhepatic cell lines HeLa and 293 support efficient replication of the hepatitis C virus genotype 2a subgenomic replicon.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Sequence analysis of hepatitis C virus isolated from a fulminant hepatitis patient

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Impaired antiviral response in human hepatoma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Subgenomic replicon derived from a cell line infected with the hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

The Level of CD81 Cell Surface Expression Is a Key Determinant for Productive Entry of Hepatitis C Virus into Host Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Antiviral effect and virus-host interactions in response to alpha interferon, gamma interferon, poly(i)-poly(c), tumor necrosis factor alpha, and ribavirin in hepatitis C virus subgenomic replicons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Infectious cDNA clone of the hepatitis C virus genotype 1 prototype sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Hepatitis C virus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Replication of a novel subgenomic HCV genotype 1a replicon expressing a puromycin resistance gene in Huh-7 cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Complete replication of hepatitis C virus in cell culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Structure of the catalytic domain of the hepatitis C virus NS2-3 protease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Introduction of NS5A mutations enables subgenomic HCV replicon derived from chimpanzee-infectious HC-J4 isolate to replicate efficiently in Huh-7 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Persistent Replication of Hepatitis C Virus Replicons Expressing the -Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Reduction of hepatitis C virus NS5A hyperphosphorylation by selective inhibition of cellular kinases activates viral RNA replication in cell culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Persistent and transient replication of full-length hepatitis C virus genomes in cell culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Characterization of cell lines carrying self-replicating hepatitis C virus RNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Binding of hepatitis C virus to CD81

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Translation initiation by factor-independent binding of eukaryotic ribosomes to internal ribosomal entry sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Hepatitis C virus glycoproteins interact with DC-SIGN and DC-SIGNR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Adenovirus-mediated gene transfer of interferon alpha inhibits hepatitis C virus replication in hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

A novel sequence found at the 3' terminus of hepatitis C virus genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Emergence of a distinct pattern of viral mutations in chimpanzees infected with a homogeneous inoculum of hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Dissecting the interferon-induced inhibition of hepatitis C virus replication by using a novel host cell line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Identification of novel HCV subgenome replicating persistently in chronic active hepatitis C patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Genetic organization and diversity of the 3' noncoding region of the hepatitis C virus genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Subgenomic hepatitis C virus replicons inducing expression of a secreted enzymatic reporter protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

3' nontranslated RNA signals required for replication of hepatitis C virus RNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Structure-function analysis of the 3' stem-loop of hepatitis C virus genomic RNA and its role in viral RNA replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Adaptive mutations producing efficient replication of genotype 1a hepatitis C virus RNA in normal Huh7 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

A cis-acting replication element in the sequence encoding the NS5B RNA-dependent RNA polymerase is required for hepatitis C virus RNA replication

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Robust hepatitis C virus infection in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Replication of Hepatitis C Virus Subgenomes in Nonhepatic Epithelial and Mouse Hepatoma Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

Kinetic and structural analyses of hepatitis C virus polyprotein processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

7 January 2021

Secondary structure determination of the conserved 98-base sequence at the 3' terminus of hepatitis C virus genome RNA

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

7 January 2021

Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

7 January 2021

Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2007.02.022

7 January 2021

10.1016/J.VIRUSRES.2007.02.022

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

17428568