(Q34618835)

English

The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo (English)

1 reference

Europe PubMed Central

3 August 2017

neoplastic invasiveness

1 reference

based on heuristic

inferred from title

7

object named as

Numsen Hail

0 references

object named as

Ye Chen

3

0 references

Marina Konopleva

8

object named as

Marina Konopleva

1 reference

Europe PubMed Central

3 August 2017

Michael Andreeff

9

object named as

Michael Andreeff

1 reference

Europe PubMed Central

3 August 2017

Wendy D Schober

6

object named as

Wendy Schober

1 reference

Europe PubMed Central

3 August 2017

1

object named as

Xiaoyang Ling

1 reference

Europe PubMed Central

3 August 2017

2

object named as

Erika Spaeth

1 reference

Europe PubMed Central

3 August 2017

author name string

Yuexi Shi

4

1 reference

Europe PubMed Central

3 August 2017

Weiguo Zhang

5

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

6 March 2013

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

8

1 reference

Europe PubMed Central

3 August 2017

3

1 reference

Europe PubMed Central

3 August 2017

e58426

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

6 March 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3590173/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The differences in CXCR4 protein expression are significant for the five molecular subtypes of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

New insight into the SDF-1/CXCR4 axis in a breast carcinoma model: hypoxia-induced endothelial SDF-1 and tumor cell CXCR4 are required for tumor cell intravasation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic niche

1 reference

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Recruitment of myeloid but not endothelial precursor cells facilitates tumor regrowth after local irradiation

1 reference

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EGFR variant-mediated invasion by enhanced CXCR4 expression through transcriptional and post-translational mechanisms

1 reference

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Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches

1 reference

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CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure

1 reference

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Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

1 reference

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Contributions of integrin-linked kinase to breast cancer metastasis and tumourigenesis.

1 reference

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Mitochondrial reactive oxygen species affect sensitivity to curcumin-induced apoptosis

1 reference

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7 July 2018

Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

1 reference

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7 July 2018

Genetic determinants of cancer metastasis

1 reference

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7 July 2018

Inhibition of CXCR4-mediated breast cancer metastasis: a potential role for heparinoids?

1 reference

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Blocking CXCR4-mediated cyclic AMP suppression inhibits brain tumor growth in vivo

1 reference

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7 July 2018

The role of the organ microenvironment in the biology and therapy of cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Preparing the "soil": the premetastatic niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Multipotent mesenchymal stromal cell recruitment, migration, and differentiation: what have matrix metalloproteinases got to do with it?

1 reference

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7 July 2018

CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Knockdown of STAT3 expression by RNA interference inhibits the induction of breast tumors in immunocompetent mice

1 reference

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7 July 2018

Identification of the cytoplasmic domains of CXCR4 involved in Jak2 and STAT3 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

CXCR4 regulates growth of both primary and metastatic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

1 reference

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7 July 2018

Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis

1 reference

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7 July 2018

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

1 reference

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Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.

1 reference

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7 July 2018

Stromal effects on mammary gland development and breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Involvement of chemokine receptors in breast cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3590173

7 July 2018

Identification and characterization of small molecule functional antagonists of the CCR1 chemokine receptor

1 reference

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7 July 2018

Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor

1 reference

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7 July 2018

Phosphorylated CXCR4 is associated with poor survival in adults with B-acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0058426

21 January 2018

CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0058426

21 January 2018

Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0058426

21 January 2018

The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0058426

21 January 2018

Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0058426

21 January 2018

Breast-Cancer Stromal Cells withTP53Mutations and Nodal Metastases

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0058426

21 January 2018

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0058426

21 January 2018

CXC chemokine receptor-4 antagonist blocks both growth of primary tumor and metastasis of head and neck cancer in xenograft mouse models

1 reference

https://pubmed.ncbi.nlm.nih.gov/23484027

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0058426

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...858426L

0 references

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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