(Q34619243)

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Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: apoptosis through the formation of 3-hydroxykynurenine

scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Induction of indoleamine 2,3-dioxygenase by interferon-gamma in human lens epithelial cells: apoptosis through the formation of 3-hydroxykynurenine (English)

1 reference

Europe PubMed Central

3 August 2017

1-methyltryptophan

1 reference

ChEBI release 2020-05-28

author name string

Maneesh Mailankot

1

1 reference

Europe PubMed Central

3 August 2017

Ram H Nagaraj

2

1 reference

Europe PubMed Central

3 August 2017

publication date

6 May 2010

1 reference

Europe PubMed Central

3 August 2017

International Journal of Biochemistry & Cell Biology

1 reference

Europe PubMed Central

3 August 2017

42

1 reference

Europe PubMed Central

3 August 2017

9

1 reference

Europe PubMed Central

3 August 2017

1446-1454

1 reference

Europe PubMed Central

3 August 2017

Proinflammatory cytokine interferon-gamma increases induction of indoleamine 2,3-dioxygenase in monocytic cells primed with amyloid beta peptide 1-42: implications for the pathogenesis of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Indoleamine 2,3-dioxygenase overexpression causes kynurenine-modification of proteins, fiber cell apoptosis and cataract formation in the mouse lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Interferon-gamma: a historical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Curcumin suppresses the induction of indoleamine 2,3-dioxygenase by blocking the Janus-activated kinase-protein kinase Cdelta-STAT1 signaling pathway in interferon-gamma-stimulated murine dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Cell cycle arrest by kynurenine in lens epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Detection of kynurenine modifications in proteins using a monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Molecules in focus: indoleamine 2,3-dioxygenase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Immune cell-specific amplification of interferon signaling by the IRF-4/8-PU.1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Paediatric uveitis: a Sydney clinic experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Degree, duration, and causes of visual loss in uveitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Interferon-gamma induces apoptosis of lens alphaTN4-1 cells and proteasome inhibition has an antiapoptotic effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Regulation of indoleamine 2,3-dioxygenase, the first enzyme in UV filter biosynthesis in the human lens. Relevance for senile nuclear cataract.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Analysis of immunoregulatory cytokines in ocular fluid samples from patients with uveitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Hydrogen peroxide-mediated neuronal cell death induced by an endogenous neurotoxin, 3-hydroxykynurenine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Cataract extraction in uveitis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

7 July 2018

Uveitis in childhood: an Italian clinical and epidemiological study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Uveitis in patients with autoimmune hepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Deaminated UV filter 3-hydroxykynurenine O-beta-D-glucoside is found in cataractous human lenses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Genetic polymorphisms in the promoter of the interferon gamma receptor 1 gene are associated with atopic cataracts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Interferon-gamma induces regression of epithelial cell carcinoma: critical roles of IRF-1 and ICSBP transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

3-Hydroxykynurenine oxidizes alpha-crystallin: potential role in cataractogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Indoleamine 2,3-dioxygenase protects corneal endothelial cells from UV mediated damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Protein-bound kynurenine is a photosensitizer of oxidative damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Glutathione and NADH, but not ascorbate, protect lens proteins from modification by UV filters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Human lens coloration and aging. Evidence for crystallin modification by the major ultraviolet filter, 3-hydroxy-kynurenine O-beta-D-glucoside.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2910246

26 October 2018

Cytokine profile in aqueous humor and sera of patients with infectious or noninfectious uveitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-bound UV filters in normal human lenses: the concentration of bound UV filters equals that of free UV filters in the center of older lenses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-bound and free UV filters in cataract lenses. The concentration of UV filters is much lower than in normal lenses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines, chemokines and soluble adhesion molecules in aqueous humor of children with uveitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term follow-up of patients with uveitis associated with juvenile idiopathic arthritis: a cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aqueous and serum interferon gamma, interleukin (IL) 2, IL-4, and IL-10 in patients with uveitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-oxidative modification of lens crystallins by kynurenine: a novel post-translational protein modification with possible relevance to ageing and cataract

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Hydroxykynurenine and 3-Hydroxyanthranilic Acid Generate Hydrogen Peroxide and Promote α-Crystallin Cross-Linking by Metal Ion Reduction†

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UV filters in human lenses: tryptophan catabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The modification of proteins by 3-hydroxykynurenine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect and recovery of long-term H2O2 exposure on lens morphology and biochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic expression of gamma interferon in the eyes of transgenic mice induces ocular pathology and MHC class II gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20435158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BIOCEL.2010.04.014

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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