(Q37293658)

English

Indoleamine 2,3-dioxygenase overexpression causes kynurenine-modification of proteins, fiber cell apoptosis and cataract formation in the mouse lens

scientific article published on 23 March 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Indoleamine 2,3-dioxygenase overexpression causes kynurenine-modification of proteins, fiber cell apoptosis and cataract formation in the mouse lens (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

apoptotic process

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1 reference

based on heuristic

inferred from title

Magdalena Maria Staniszewska

2

object named as

Magdalena M Staniszewska

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Maneesh Mailankot

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Heather Butler

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Moonkyung H Caprara

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Scott Howell

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Benlian Wang

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Catherine Doller

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Lixing W Reneker

8

1 reference

Europe PubMed Central

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19 August 2017

Ram H Nagaraj

9

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Europe PubMed Central

PMC publication ID

19 August 2017

publication date

23 March 2009

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Europe PubMed Central

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19 August 2017

Laboratory Investigation

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Europe PubMed Central

PMC publication ID

19 August 2017

89

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

498-512

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

https://scigraph.springernature.com/pub.10.1038/labinvest.2009.22

0 references

Tumor immune escape mediated by indoleamine 2,3-dioxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Role of indoleamine 2,3-dioxygenase in antimicrobial defence and immuno-regulation: tryptophan depletion versus production of toxic kynurenines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Tryptophan catabolism in IDO+ plasmacytoid dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Molecules in focus: indoleamine 2,3-dioxygenase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Inhibition of indoleamine 2,3 dioxygenase activity by H2O2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Mini-alphaB-crystallin: a functional element of alphaB-crystallin with chaperone-like activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Caspase-dependent secondary lens fiber cell disintegration in alphaA-/alphaB-crystallin double-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

UV filters in the lens of the thirteen lined ground squirrel (Spermophilus tridecemlineatus).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Biochemical and medical aspects of the indoleamine 2,3-dioxygenase-initiated L-tryptophan metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Monitoring tryptophan metabolism in chronic immune activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Growth factor regulation of lens development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Tryptophan catabolism and T cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Immune activation and degradation of tryptophan in coronary heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Neuronal apoptosis induced by pharmacological concentrations of 3-hydroxykynurenine: characterization and protection by dantrolene and Bcl-2 overexpression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Glutathione: a vital lens antioxidant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Regulation of mouse lens fiber cell development and differentiation by the Maf gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Prox1 function is crucial for mouse lens-fibre elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

6 September 2017

Detection of kynurenine modifications in proteins using a monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

14 September 2017

Interferon-gamma induces apoptosis of lens alphaTN4-1 cells and proteasome inhibition has an antiapoptotic effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

14 September 2017

Lens differentiation in vertebrates. A review of cellular and molecular features

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

14 September 2017

3-Hydroxyanthranilic acid, an L-tryptophan metabolite, induces apoptosis in monocyte-derived cells stimulated by interferon-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

28 September 2017

Regulation of indoleamine 2,3-dioxygenase, the first enzyme in UV filter biosynthesis in the human lens. Relevance for senile nuclear cataract.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

28 September 2017

Major changes in human ocular UV protection with age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

26 June 2018

Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

26 June 2018

Metabolism and function of glutathione in the lens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

26 June 2018

Rise and fall of crystallin gene messenger levels during fibroblast growth factor induced terminal differentiation of lens cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

26 June 2018

Kynurenine pathway abnormalities in Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

26 June 2018

Proapoptotic activity of indoleamine 2,3-dioxygenase expressed in renal tubular epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Local expression of indoleamine 2,3-dioxygenase protects engraftment of xenogeneic skin substitute

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Human alpha-1-microglobulin is covalently bound to kynurenine-derived chromophores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Kidney and liver kynurenine pathway enzymes in chronic renal failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

T cell apoptosis by kynurenines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Protein-bound kynurenine decreases with the progression of age-related nuclear cataract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Neurotoxic and neurobehavioral effects of kynurenines in adult insects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

The effect of elevated intraocular oxygen on organelle degradation in the embryonic chicken lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

UV filter instability: consequences for the human lens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Rho GTPase inactivation impairs lens growth and integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Novel protein modification by kynurenine in human lenses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Kynurenine binds to the peptide binding region of the chaperone alphaB-crystallin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Disruption of lens fiber cell differentiation and survival at multiple stages by region-specific expression of truncated FGF receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722445

3 September 2018

L-tryptophan-kynurenine pathway metabolite 3-hydroxyanthranilic acid induces apoptosis in macrophage-derived cells under pathophysiological conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aqueous and serum interferon gamma, interleukin (IL) 2, IL-4, and IL-10 in patients with uveitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect and recovery of long-term H2O2 exposure on lens morphology and biochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione levels of the human crystalline lens in aging and its antioxidant effect against the oxidation of lens proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice expressing IFN-gamma in the retina develop inflammation of the eye and photoreceptor loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An investigation of the activities of 3-hydroxykynureninase and kynurenine aminotransferase in the brain in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase is necessary for lens fiber cell differentiation and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein-bound UV filters in normal human lenses: the concentration of bound UV filters equals that of free UV filters in the center of older lenses

1 reference

https://pubmed.ncbi.nlm.nih.gov/19308046

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/LABINVEST.2009.22

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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