(Q34621573)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

0 references

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Marco Antônio Ataíde

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Ricardo Gazzinelli

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

10

Douglas T Golenbock

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Sally T Ishizaka

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Marc Lamphier

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Fabian Gusovsky

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Hans Hansen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Jeffrey Rose

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Wanjun Zheng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Rosane B de Oliveira

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

8 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

3689-3694

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Hemozoin (malarial pigment) directly promotes apoptosis of erythroid precursors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endothelium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Artemisinin Resistance in Plasmodium falciparum Malaria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

A world malaria map: Plasmodium falciparum endemicity in 2007

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Malaria primes the innate immune response due to interferon-gamma induced enhancement of toll-like receptor expression and function.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

STAT6-mediated suppression of erythropoiesis in an experimental model of malarial anemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Enhanced toll-like receptor responsiveness associated with mitogen-activated protein kinase activation in Plasmodium falciparum-infected children

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

TLR7/9 antagonists as therapeutics for immune-mediated inflammatory disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Malaria: mechanisms of erythrocytic infection and pathological correlates of severe disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

New concepts in antimalarial use and mode of action in dermatology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Murine cerebral malaria development is independent of toll-like receptor signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Human malarial disease: a consequence of inflammatory cytokine release

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Common and divergent immune response signaling pathways discovered in peripheral blood mononuclear cell gene expression patterns in presymptomatic and clinically apparent malaria.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Malaria tolerance--for whom the cell tolls?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Immunopathogenesis of cerebral malaria.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Interaction of mouse dendritic cells and malaria-infected erythrocytes: uptake, maturation, and antigen presentation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Dendritic cells, pro-inflammatory responses, and antigen presentation in a rodent malaria infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

The anemia of malaria infection: role of inflammatory cytokines.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Effects of chloroquine on viral infections: an old drug against today's diseases?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

A retrospective examination of anemia during infection of humans with Plasmodium vivax

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Evaluation of the pyrogenic threshold for Plasmodium falciparum malaria in naive individuals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Mechanism of action of hydroxychloroquine as an antirheumatic drug

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Does endotoxin cause both the disease and parasite death in acute malaria and babesiosis?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048158

Malaria: the end of the beginning

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

Pathological role of Toll-like receptor signaling in cerebral malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

Plasmodium falciparum infection causes proinflammatory priming of human TLR responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

MyD88-dependent activation of dendritic cells and CD4(+) T lymphocytes mediates symptoms, but is not required for the immunological control of parasites during rodent malaria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

Transgenic mice expressing high levels of soluble TNF-R1 fusion protein are protected from lethal septic shock and cerebral malaria, and are highly sensitive to Listeria monocytogenes and Leishmania major infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

Depletion of CD4+ or CD8+ T-cells prevents Plasmodium berghei induced cerebral malaria in end-stage disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1015406108

The effect of hydroxychloroquine therapy on serum levels of immunoregulatory molecules in patients with systemic lupus erythematosus

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21303985

12 December 2020

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/21303985

12 December 2020

inferred from PubMed ID database lookup

The duration of untreated or inadequately treated Plasmodium falciparum infections in the human host

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21303985

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1015406108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21303985%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21303985

1 reference