(Q34622392)

3 August 2017

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title

Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments (English)

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3 August 2017

H Blumberg

3

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author name string

J H Krystal

1

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3 August 2017

G Sanacora

2

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3 August 2017

A Anand

4

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3 August 2017

D S Charney

5

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3 August 2017

G Marek

6

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3 August 2017

C N Epperson

7

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3 August 2017

A Goddard

8

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3 August 2017

G F Mason

9

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3 August 2017

language of work or name

English

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publication date

1 January 2002

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3 August 2017

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3 August 2017

7 Suppl 1

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3 August 2017

S71-80

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https://scigraph.springernature.com/pub.10.1038/sj.mp.4001021

3 August 2017

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Impairment of GABAergic transmission in depression: new insights from neuroimaging studies

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21 January 2018

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Glial reduction in the subgenual prefrontal cortex in mood disorders

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Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression.

21 January 2018

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21 January 2018

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21 January 2018

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Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain.

21 January 2018

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Prefrontal cortical-amygdalar metabolism in major depression

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Increased anterior cingulate and caudate activity in bipolar mania

21 January 2018

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Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders

21 January 2018

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Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.

21 January 2018

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Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR.

21 January 2018

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Reduced glutamate in the anterior cingulate cortex in depression: an in vivo proton magnetic resonance spectroscopy study

21 January 2018

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Single doses of MK-801, a non-competitive antagonist of NMDA receptors, increase the number of 5-HT1A serotonin receptors in the rat brain.

21 January 2018

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N-methyl-d-aspartate receptors regulate 5-HT release in the raphe nuclei and frontal cortex of freely moving rats: differential role of 5-HT1A autoreceptors.

21 January 2018

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Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats.

21 January 2018

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Tricyclic antidepressants block N-methyl-D-aspartate receptors: similarities to the action of zinc

21 January 2018

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Inhibition of N-methyl-l-aspartate activated ion current by desmethylimipramine

21 January 2018

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Characterization of a [3H]glycine recognition site as a modulatory site of the N-methyl-D-aspartate receptor complex

21 January 2018

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Actions of D-cycloserine at the N-methyl-D-aspartate-associated glycine receptor site in vivo

21 January 2018

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Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

21 January 2018

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Possible use of amantadine in depression

21 January 2018

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Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents--preclinical studies.

21 January 2018

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Therapeutic brain concentration of the NMDA receptor antagonist amantadine

21 January 2018

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Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.

21 January 2018

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Amantadine in depression.

21 January 2018

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Amantadine and human Borna disease virus in vitro and in vivo in an infected patient with bipolar depression

21 January 2018

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Amantadine-induced aggressiveness

21 January 2018

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Treatment of Impaired Cerebral Function in Psychogeriatric Patients with Memantine - Results of a Phase II Double-Blind Study

21 January 2018

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Antidepressant effects of ketamine in depressed patients

21 January 2018

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Mechanism of disinhibition after brain lesions

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Prefrontal cortex regulates inhibition and excitation in distributed neural networks

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

21 January 2018

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An in vitro electrophysiological study on the effects of phenytoin, lamotrigine and gabapentin on striatal neurons

21 January 2018

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Effect of carbamazepine, oxcarbazepine and lamotrigine on the increase in extracellular glutamate elicited by veratridine in rat cortex and striatum.

21 January 2018

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21 January 2018

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5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

21 January 2018

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Serotonin model of schizophrenia: emerging role of glutamate mechanisms

21 January 2018

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A comparison of trazodone and fluoxetine: implications for a serotonergic mechanism of antidepressant action

21 January 2018

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Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

21 January 2018

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Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers

21 January 2018

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Differential psychopathology and patterns of cerebral glucose utilisation produced by (S)- and (R)-ketamine in healthy volunteers using positron emission tomography (PET)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Attenuation of ketamine effects by nimodipine pretreatment in recovering ethanol dependent men: psychopharmacologic implications of the interaction of NMDA and L-type calcium channel antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Comparison of clonidine and lithium in the treatment of mania

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Clinical studies of induction agents. 38. Effect of premedicants and supplements on ketamine anaesthesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

GABA and mood disorders: a brief review and hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Role of 5-HT2A receptors in the stress-induced down-regulation of brain-derived neurotrophic factor expression in rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Reliability of a lifetime history of major depression: implications for heritability and co-morbidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

The relationship between panic disorder and major depression. A new family study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Allopregnanolone concentrations and premenstrual syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Progesterone metabolite allopregnanolone in women with premenstrual syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

GABAergic modulation of learned helplessness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

The gabaergic hypothesis of depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

The effect of repeated electroconvulsive shock on GABA synthesis and release in regions of rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Low brain GABA level is associated with poor seizure control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Human brain GABA levels rise rapidly after initiation of vigabatrin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

A functional anatomical study of unipolar depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Hippocampal volume in geriatric depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

D-serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Alterations in the N-methyl-d-asparatate (NMDA) receptor complex in the frontal cortex of suicide victims

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Blockade of transmission at NMDA receptors facilitates the electrical and synthetic activity of ascending serotoninergic neurones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Swim Stress Increases the Potency of Glycine at the N-Methyl-d-Aspartate Receptor Complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Drugs of abuse and stress increase the expression of GluR1 and NMDAR1 glutamate receptor subunits in the rat ventral tegmental area: common adaptations among cross-sensitizing agents.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Cyloserine as an antidepressant agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Amantadine dosage in treatment of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

The anticonvulsant, lamotrigine decreases spontaneous glutamate release but increases spontaneous GABA release in the rat entorhinal cortex in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Effects of anticonvulsants on veratridine- and KCl-evoked glutamate release from rat cortical synaptosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

DOI-Induced activation of the cortex: dependence on 5-HT2A heteroceptors on thalamocortical glutamatergic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

NMDA-dependent modulation of CA1 local circuit inhibition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Ketamine activates psychosis and alters limbic blood flow in schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Double-blind comparison of the effects of clonazepam and lorazepam in acute mania

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Depression among alcoholics. Relationship to clinical and cerebrospinal fluid variables

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Brain-derived neurotrophic factor mediates the activity-dependent regulation of inhibition in neocortical cultures.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Different mechanisms of protection against apoptosis by valproate and Li+

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001021

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001021

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference