(Q34623585)

3 August 2017

Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure (English)

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3 August 2017

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Ying Chen

1

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3 August 2017

Yi Yang

2

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3 August 2017

Marian L Miller

3

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3 August 2017

Dongxiao Shen

4

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3 August 2017

Howard G Shertzer

5

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3 August 2017

Keith F Stringer

6

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3 August 2017

Bin Wang

7

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3 August 2017

Scott N Schneider

8

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3 August 2017

Daniel W Nebert

9

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3 August 2017

Timothy P Dalton

10

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3 August 2017

language of work or name

English

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publication date

1 May 2007

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3 August 2017

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3 August 2017

45

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3 August 2017

5

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3 August 2017

1118-1128

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Glutathione replenishment capacity is lower in isolated perivenous than in periportal hepatocytes

3 August 2017

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The distribution of glutathione in the rat liver lobule

21 January 2018

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Mitochondrial changes associated with glutathione deficiency

21 January 2018

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Survival and cell death in cells constitutively unable to synthesize glutathione.

21 January 2018

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Regulation of hepatic glutathione metabolism and its role in hepatotoxicity

21 January 2018

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Genetically altered mice to evaluate glutathione homeostasis in health and disease

21 January 2018

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7 January 2021

Biologic and pharmacologic regulation of mammalian glutathione synthesis

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7 January 2021

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

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7 January 2021

Metabolism and function of glutathione: an overview

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7 January 2021

Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels

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7 January 2021

Expression and purification of human gamma-glutamylcysteine synthetase

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7 January 2021

Nutritional and hormonal regulation of glutathione homeostasis

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7 January 2021

Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

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7 January 2021

Glutathione synthesis is essential for mouse development but not for cell growth in culture

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7 January 2021

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

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7 January 2021

Detoxification of reactive oxygen species by a nonpeptidyl mimic of superoxide dismutase cures acetaminophen-induced acute liver failure in the mouse

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7 January 2021

Cytochrome P450 and liver diseases

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7 January 2021

Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress

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7 January 2021

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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7 January 2021

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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7 January 2021

Dioxin increases reactive oxygen production in mouse liver mitochondria

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7 January 2021

Determining glutathione and glutathione disulfide using the fluorescence probe o-phthalaldehyde

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7 January 2021

Enzyme induction by L-buthionine (S,R)-sulfoximine in cultured mouse hepatoma cells.

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7 January 2021

Glutathione redox state regulates mitochondrial reactive oxygen production

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7 January 2021

Intervention in free radical mediated hepatotoxicity and lipid peroxidation by indole-3-carbinol

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7 January 2021

Distribution of organelles and membranes between hepatocytes and nonhepatocytes in the rat liver parenchyma. A stereological study

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7 January 2021

Glutathione metabolism during aging and in Alzheimer disease

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7 January 2021

Thiol-dependent peroxidases care little about homology-based assignments of function

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7 January 2021

Origin and turnover of mitochondrial glutathione

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7 January 2021

Glutathione depleting agents and lipid peroxidation

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7 January 2021

The heme-responsive element of the mouse heme oxygenase-1 gene is an extended AP-1 binding site that resembles the recognition sequences for MAF and NF-E2 transcription factors

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7 January 2021

Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress

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7 January 2021

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements

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7 January 2021

Differential expression of albumin and α-fetoprotein genes in fetal tissues of mouse and rat

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7 January 2021

Mechanistic aspects of enhanced lipid peroxidation following glutathione depletion in vivo

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7 January 2021

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function

1 reference

7 January 2021

Involvement of the cystathionine pathway in the biosynthesis of glutathione by isolated rat hepatocytes

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7 January 2021

The regulation of hepatic glutathione

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7 January 2021

Hepatic glutathione homeostasis in the rat: efflux accounts for glutathione turnover.

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7 January 2021

Mitochondria in steatohepatitis

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7 January 2021

The ins and outs of mitochondrial dysfunction in NASH.

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7 January 2021

Identifiers

DOI

10.1002/HEP.21635

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3 August 2017

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