(Q34623816)

3 August 2017

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title

Opinion: peroxisomal-protein import: is it really that complex? (English)

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protein import into peroxisome matrix

3 August 2017

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0016558

protein import into peroxisome matrix, docking

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Gene Ontology release 2020-05-02

1

Stephen J Gould

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3 August 2017

Cynthia S Collins

2

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PubMed ID

11988772

3 August 2017

language of work or name

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1 May 2002

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Nature Reviews Molecular Cell Biology

3 August 2017

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3 August 2017

3

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3 August 2017

382-389

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3 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/nrm807

3 August 2017

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cites work

Protein translocation across membranes

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An oligomeric protein is imported into peroxisomes in vivo

31 March 2020

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Saccharomyces cerevisiae peroxisomal thiolase is imported as a dimer.

31 March 2020

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Import of stably folded proteins into peroxisomes

31 March 2020

1 reference

Involvement of 70-kD heat-shock proteins in peroxisomal import

31 March 2020

1 reference

A conserved tripeptide sorts proteins to peroxisomes

31 March 2020

1 reference

Protein import into peroxisomes and biogenesis of the organelle

31 March 2020

1 reference

Peroxisomal targeting signal-1 recognition by the TPR domains of human PEX5

31 March 2020

1 reference

The genetics of peroxisome biogenesis

31 March 2020

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The mammalian peroxin Pex5pL, the longer isoform of the mobile peroxisome targeting signal (PTS) type 1 transporter, translocates the Pex7p.PTS2 protein complex into peroxisomes via its initial docking site, Pex14p

31 March 2020

1 reference

Domain mapping of human PEX5 reveals functional and structural similarities to Saccharomyces cerevisiae Pex18p and Pex21p

31 March 2020

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Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes

31 March 2020

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Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor

31 March 2020

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Peroxisome biogenesis disorders: genetics and cell biology

31 March 2020

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Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways

31 March 2020

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Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor

31 March 2020

1 reference

The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins.

31 March 2020

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Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor

31 March 2020

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PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import

31 March 2020

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Pex8p, an intraperoxisomal peroxin of Saccharomyces cerevisiae required for protein transport into peroxisomes binds the PTS1 receptor pex5p

31 March 2020

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Molecular anatomy of the peroxin Pex12p: ring finger domain is essential for Pex12p function and interacts with the peroxisome-targeting signal type 1-receptor Pex5p and a ring peroxin, Pex10p

31 March 2020

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The ubiquitin-conjugating enzyme Pex4p of Hansenula polymorpha is required for efficient functioning of the PTS1 import machinery

31 March 2020

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The peroxisome biogenesis factors pex4p, pex22p, pex1p, and pex6p act in the terminal steps of peroxisomal matrix protein import

31 March 2020

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Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane

31 March 2020

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Translocation of acyl-CoA oxidase into peroxisomes requires ATP hydrolysis but not a membrane potential

31 March 2020

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Cytosol-dependent peroxisomal protein import in a permeabilized cell system

31 March 2020

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Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14.

31 March 2020

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Metabolic pathways in peroxisomes and glyoxysomes

31 March 2020

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Peroxisomal beta-oxidation enzymes

31 March 2020

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The di-aromatic pentapeptide repeats of the human peroxisome import receptor PEX5 are separate high affinity binding sites for the peroxisomal membrane protein PEX14.

31 March 2020

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Biogenesis of peroxisomes

31 March 2020

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Proton ionophores prevent assembly of a peroxisomal protein

31 March 2020

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Hsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1

31 March 2020

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PTS2 protein import into mammalian peroxisomes

31 March 2020

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The cytosolic DnaJ-like protein djp1p is involved specifically in peroxisomal protein import

31 March 2020

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Protein unfolding by mitochondria. The Hsp70 import motor

31 March 2020

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AAA proteins. Lords of the ring

31 March 2020

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The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor

31 March 2020

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Mutations in PEX1 are the most common cause of peroxisome biogenesis disorders

31 March 2020

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Peroxisomes are formed from complex membrane structures in PEX6-deficient CHO cells upon genetic complementation.

31 March 2020

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Cloning and characterization of PAS5: a gene required for peroxisome biogenesis in the methylotrophic yeast Pichia pastoris

31 March 2020

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Role of the PAS1 gene of Pichia pastoris in peroxisome biogenesis

31 March 2020

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

31 March 2020

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

31 March 2020

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The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

31 March 2020

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The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation

31 March 2020

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The human peroxisomal targeting signal receptor, Pex5p, is translocated into the peroxisomal matrix and recycled to the cytosol

31 March 2020

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Peroxisomal protein import. the paradigm shifts

31 March 2020

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Protein translocation: tunnel vision

31 March 2020

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The translocon: a dynamic gateway at the ER membrane

31 March 2020

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Acyl-CoA oxidase is imported as a heteropentameric, cofactor-containing complex into peroxisomes of Yarrowia lipolytica

31 March 2020

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Topology of catalase assembly in human skin fibroblasts

31 March 2020

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Peroxisomes in human fibroblasts have a basic pH

31 March 2020

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Three-dimensional ultrastructure of normal rat hepatocytes by quick-freezing and deep-etching method

31 March 2020

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A freeze-etch study of angular marginal-plate-containing peroxisomes in the proximal tubules of bovine kidney

31 March 2020

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How proteins penetrate peroxisomes

31 March 2020

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Characterization of peroxisomal Pex5p from rat liver. Pex5p in the Pex5p-Pex14p membrane complex is a transmembrane protein

31 March 2020

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The Hansenula polymorpha PER3 gene is essential for the import of PTS1 proteins into the peroxisomal matrix.

31 March 2020

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Identification and characterization of the putative human peroxisomal C-terminal targeting signal import receptor

31 March 2020

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Biogenesis of peroxisomal proteins in vivo and in vitro

31 March 2020

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Overproduction of Pex5p stimulates import of alcohol oxidase and dihydroxyacetone synthase in a Hansenula polymorpha Pex14 null mutant.

31 March 2020

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31 March 2020

Peroxisome biogenesis

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31 March 2020

Peroxisomes of protozoa

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Biology of Giardia lamblia

31 March 2020

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Inactivation of the endoplasmic reticulum protein translocation factor, Sec61p, or its homolog, Ssh1p, does not affect peroxisome biogenesis

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRM807

1 reference

PubMed ID

11988772

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

11988772