(Q34624051)

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Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21199869%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21199869%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

G protein-coupled receptor

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2

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19 January 2020

author name string

Chih-chin Huang

1

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19 January 2020

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3 January 2011

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19 January 2020

Journal of Biological Chemistry

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19 January 2020

286

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19 January 2020

7715-7721

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19 January 2020

10

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Europe PubMed Central

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19 January 2020

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Differential signaling of the endogenous agonists at the beta2-adrenergic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Molecular basis for activation of G protein-coupled receptor kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Teaching old receptors new tricks: biasing seven-transmembrane receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Monomeric rhodopsin is the minimal functional unit required for arrestin binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

A G protein-coupled receptor at work: the rhodopsin model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structural and kinetic modeling of an activating helix switch in the rhodopsin-transducin interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The structure and function of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

GRK2 activation by receptors: role of the kinase large lobe and carboxyl-terminal tail.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Topology of class A G protein-coupled receptors: insights gained from crystal structures of rhodopsins, adrenergic and adenosine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Crystal structure of opsin in its G-protein-interacting conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structure of a beta1-adrenergic G-protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Crystal structure of the ligand-free G-protein-coupled receptor opsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Crystal structure of squid rhodopsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structural basis of effector regulation and signal termination in heterotrimeric Galpha proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Conformational complexity of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Transducin activation by nanoscale lipid bilayers containing one and two rhodopsins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structural basis of function in heterotrimeric G proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Differential interaction of spin-labeled arrestin with inactive and active phosphorhodopsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The structural basis of arrestin-mediated regulation of G-protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structure of bovine rhodopsin in a trigonal crystal form.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Probing the mechanism of rhodopsin-catalyzed transducin activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The A326S mutant of Gialpha1 as an approximation of the receptor-bound state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Light-activated rhodopsin induces structural binding motif in G protein alpha subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

GTP-binding-protein-coupled receptor kinases--two mechanistic models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048657

7 July 2018

Rhodopsin determinants for transducin activation: a gain-of-function approach

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R109.051847

21 January 2018

The interaction with the cytoplasmic loops of rhodopsin plays a crucial role in arrestin activation and binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R109.051847

21 January 2018

Conformations of the active and inactive states of opsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R109.051847

21 January 2018

Rhodopsin activation exposes a key hydrophobic binding site for the transducin alpha-subunit C terminus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R109.051847

21 January 2018

Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R109.051847

21 January 2018

Signal transfer from GPCRs to G proteins: role of the G alpha N-terminal region in rhodopsin-transducin coupling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R109.051847

21 January 2018

The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R109.051847

21 January 2018

Rhodopsin recognition by mutant G(s)alpha containing C-terminal residues of transducin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of G-protein Galpha subunits by receptors through Galpha-Gbeta and Galpha-Ggamma interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of rhodopsin kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The receptor-bound "empty pocket" state of the heterotrimeric G-protein alpha-subunit is conformationally dynamic

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein-coupled receptor kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and function in rhodopsin: effects of disulfide cross-links in the cytoplasmic face of rhodopsin on transducin activation and phosphorylation by rhodopsin kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21199869

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.R109.051847

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21199869%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

release_kjz3nryelfagjmwumhwhvp2ifa

1 reference

https://api.fatcat.wiki/v0/release/kjz3nryelfagjmwumhwhvp2ifa

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21199869%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21199869%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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