(Q34624675)

English

Coupling deep transcriptome analysis with untargeted metabolic profiling in Ophiorrhiza pumila to further the understanding of the biosynthesis of the anti-cancer alkaloid camptothecin and anthraquinones

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Coupling deep transcriptome analysis with untargeted metabolic profiling in Ophiorrhiza pumila to further the understanding of the biosynthesis of the anti-cancer alkaloid camptothecin and anthraquinones (English)

1 reference

Europe PubMed Central

3 August 2017

0 references

Ophiorrhiza pumila

object named as

Ophiorrhiza pumila

1 reference

based on heuristic

inferred from title

metabolic profiling

1 reference

based on heuristic

inferred from title

Elsa Góngora-Castillo

object named as

Elsa Góngora-Castillo

14

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Ryo Nakabayashi

object named as

Ryo Nakabayashi

4

0 references

Tetsuya Sakurai

object named as

Tetsuya Sakurai

16

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Keiichi Mochida

object named as

Keiichi Mochida

2

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object named as

Mami Yamazaki

1

0 references

object named as

Kazuki Saito

17

0 references

12

object named as

Yasushi Totoki

1 reference

Europe PubMed Central

3 August 2017

Dayan B Goodenowe

8

object named as

Dayan B Goodenowe

1 reference

Europe PubMed Central

3 August 2017

author name string

Takashi Asano

3

1 reference

Europe PubMed Central

3 August 2017

Motoaki Chiba

5

1 reference

Europe PubMed Central

3 August 2017

Nirin Udomson

6

1 reference

Europe PubMed Central

3 August 2017

Yasuyo Yamazaki

7

1 reference

Europe PubMed Central

3 August 2017

Ushio Sankawa

9

1 reference

Europe PubMed Central

3 August 2017

Takuhiro Yoshida

10

1 reference

Europe PubMed Central

3 August 2017

Atsushi Toyoda

11

1 reference

Europe PubMed Central

3 August 2017

Yoshiyuki Sakaki

13

1 reference

Europe PubMed Central

3 August 2017

C Robin Buell

15

1 reference

Europe PubMed Central

3 August 2017

publication date

15 March 2013

1 reference

Europe PubMed Central

3 August 2017

number of pages

11

1 reference

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inferred from page(s)

Plant and Cell Physiology

1 reference

Europe PubMed Central

3 August 2017

54

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Europe PubMed Central

3 August 2017

5

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Europe PubMed Central

3 August 2017

686-696

1 reference

Europe PubMed Central

3 August 2017

Network analysis for gene discovery in plant-specialized metabolism

1 reference

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Transcriptome data modeling for targeted plant metabolic engineering

1 reference

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1 reference

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1 reference

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Cytochromes p450

1 reference

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Towards understanding how molecular networks evolve in plants

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Pyrosequencing of the Camptotheca acuminata transcriptome reveals putative genes involved in camptothecin biosynthesis and transport

1 reference

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Structures of alkaloid biosynthetic glucosidases decode substrate specificity

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Mutations in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants

1 reference

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Camptothecin: therapeutic potential and biotechnology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3653139

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Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis

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Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana

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Biosynthesis of camptothecin. In silico and in vivo tracer study from [1-13C]glucose

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1093%2FPCP%2FPCT040

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1 reference

https://api.crossref.org/works/10.1093%2FPCP%2FPCT040

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Camptothecins and two new monoterpene glucosides from Ophiorrhiza liukiuensis

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23503598

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23503598

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1 reference

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Identifiers

10.1093/PCP/PCT040

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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