(Q34628298)

3 August 2017

title

Promotion of sleep by suvorexant-a novel dual orexin receptor antagonist (English)

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3 August 2017

1

Christopher J Winrow

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3 August 2017

Anthony L Gotter

2

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3 August 2017

Christopher D Cox

3

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3 August 2017

Scott M Doran

4

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3 August 2017

Pamela L Tannenbaum

5

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3 August 2017

Michael J Breslin

6

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3 August 2017

Susan L Garson

7

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3 August 2017

Steven V Fox

8

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3 August 2017

Charles M Harrell

9

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3 August 2017

Joanne Stevens

10

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3 August 2017

Duane R Reiss

11

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3 August 2017

Donghui Cui

12

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3 August 2017

Paul J Coleman

13

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3 August 2017

John J Renger

14

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3 August 2017

publication date

1 March 2011

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3 August 2017

published in

Journal of Neurogenetics

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3 August 2017

volume

25

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3 August 2017

issue

1-2

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3 August 2017

page(s)

52-61

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Selective stimulation of orexin receptor type 2 promotes wakefulness in freely behaving rats

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Role of lateral hypothalamic orexin neurons in reward processing and addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Diagnosis and treatment of chronic insomnia: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Orexins: from neuropeptides to energy homeostasis and sleep/wake regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Hypocretins in the control of sleep and wakefulness.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Promotion of sleep by targeting the orexin system in rats, dogs and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Design and synthesis of conformationally constrained N,N-disubstituted 1,4-diazepanes as potent orexin receptor antagonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Discovery of the dual orexin receptor antagonist [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone (MK-4305) for the treatment of insomnia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Analysis of onset location, laterality and propagation of cataplexy in canine narcolepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Changes in CSF hypocretin-1 (orexin A) levels in rats across 24 hours and in response to food deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Arousal effect of orexin A depends on activation of the histaminergic system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Insomnia in the elderly: cause, approach, and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Sleep patterns and mortality among elderly patients in a geriatric hospital.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Differential expression of orexin receptors 1 and 2 in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Behavioral correlates of activity in identified hypocretin/orexin neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Behavioral state instability in orexin knock-out mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Orexin-1 receptor antagonism decreases ethanol consumption and preference selectively in high-ethanol--preferring Sprague--Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Sub-chronic administration of zolpidem affects modifications to rat sleep architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

The orexin system: roles in sleep/wake regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Discovery of a potent, CNS-penetrant orexin receptor antagonist based on an n,n-disubstituted-1,4-diazepane scaffold that promotes sleep in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Orexins activate histaminergic neurons via the orexin 2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F01677063.2011.566953

10.3109/01677063.2011.566953

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference