(Q34629065)

3 August 2017

3 references

17 June 2019

2 October 2019

11 October 2020

Astaxanthin: a potential therapeutic agent in cardiovascular disease (English)

1 reference

3 August 2017

1 reference

2 October 2019

cardiovascular disease

4 references

17 June 2019

2 October 2019

11 October 2020

1 reference

1 reference

11 October 2020

2

Jeff S Coombes

1 reference

3 August 2017

Robert G Fassett

1

1 reference

3 August 2017

publication date

21 March 2011

4 references

3 August 2017

17 June 2019

2 October 2019

11 October 2020

4 references

3 August 2017

17 June 2019

2 October 2019

11 October 2020

9

1 reference

3 August 2017

issue

3

1 reference

3 August 2017

page(s)

447-465

1 reference

Creative Commons Attribution 3.0 Unported

3 August 2017

copyright license

3 references

17 June 2019

2 October 2019

Novel astaxanthin prodrug (CDX-085) attenuates thrombosis in a mouse model

11 October 2020

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin decreased oxidative stress and inflammation and enhanced immune response in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Association between atherosclerosis and newly classified chronic kidney disease stage for Japanese patients with type 2 diabetes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Effects of astaxanthin on the production of NO and the expression of COX-2 and iNOS in LPS-stimulated BV2 microglial cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin inhibits reactive oxygen species-mediated cellular toxicity in dopaminergic SH-SY5Y cells via mitochondria-targeted protective mechanism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin vs placebo on arterial stiffness, oxidative stress and inflammation in renal transplant patients (Xanthin): a randomised controlled trial.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Effects of astaxanthin on human blood rheology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin, a dietary carotenoid, protects retinal cells against oxidative stress in-vitro and in mice in-vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Antioxidants in cardiovascular health and disease: key lessons from epidemiologic studies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin: a novel potential treatment for oxidative stress and inflammation in cardiovascular disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

The chemistry of novel xanthophyll carotenoids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Natural products as a robust source of new drugs and drug leads: past successes and present day issues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Biologic activity of carotenoids related to distinct membrane physicochemical interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Why have antioxidants failed in clinical trials?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part II: Clinical trial evidence (acute coronary syndromes through renal disease) and future directions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Antihypertensive potential and mechanism of action of astaxanthin: III. Antioxidant and histopathological effects in spontaneously hypertensive rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin, a carotenoid with potential in human health and nutrition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Disodium disuccinate astaxanthin (Cardax): antioxidant and antiinflammatory cardioprotection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Oxidative remodeling of plastid carotenoids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Oral alpha-tocopherol supplementation inhibits lipid oxidation in established human atherosclerotic lesions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Modulation of transcriptional activity by antioxidant carotenoids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF-kappaB activation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Safety of an astaxanthin-rich Haematococcus pluvialis algal extract: a randomized clinical trial

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Effects of astaxanthin on lipopolysaccharide-induced inflammation in vitro and in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Haematococcus astaxanthin: applications for human health and nutrition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Dietary antioxidants and risk of myocardial infarction in the elderly: the Rotterdam Study.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

A prospective study of consumption of carotenoids in fruits and vegetables and decreased cardiovascular mortality in the elderly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Vitamin E consumption and the risk of coronary heart disease in men.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Antioxidant vitamin intake and coronary mortality in a longitudinal population study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Carotenoid biosynthesis in microorganisms and plants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Cardiovascular disease and nutrient antioxidants: role of low-density lipoprotein oxidation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

beta-Carotene: an unusual type of lipid antioxidant

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Antioxidant functions of carotenoids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Plasma vitamins E and A inversely correlated to mortality from ischemic heart disease in cross-cultural epidemiology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a National Heart, Lung, and Blood Institute Workshop: September 5-6, 1991, Bethesda, Maryland

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Vitamin C consumption is associated with less progression in carotid intima media thickness in elderly men: A 3-year intervention study

7 July 2018

1 reference

Vitamin E consumption and the risk of coronary disease in women.

21 January 2018

1 reference

Low dietary intake of beta-carotene, alpha-tocopherol and ascorbic acid is associated with increased inflammatory and oxidative stress status in a Swedish cohort

21 January 2018

1 reference

The antioxidant acetylcysteine reduces cardiovascular events in patients with end-stage renal failure: a randomized, controlled trial

21 January 2018

1 reference

Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease

21 January 2018

1 reference

Disodium disuccinate astaxanthin prevents carotid artery rethrombosis and ex vivo platelet activation

21 January 2018

1 reference

Cardioprotection and myocardial salvage by a disodium disuccinate astaxanthin derivative (Cardax).

21 January 2018

1 reference

Seven day oral supplementation with Cardax (disodium disuccinate astaxanthin) provides significant cardioprotection and reduces oxidative stress in rats

21 January 2018

1 reference

beta-Carotene interferes with ultraviolet light A-induced gene expression by multiple pathways

21 January 2018

1 reference

Astaxanthin, canthaxanthin and beta-carotene differently affect UVA-induced oxidative damage and expression of oxidative stress-responsive enzymes

21 January 2018

1 reference

Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion

21 January 2018

1 reference

Acute and chronic administration of disodium disuccinate astaxanthin (Cardax) produces marked cardioprotection in dog hearts

21 January 2018

1 reference

Ulcer preventive and antioxidative properties of astaxanthin from Haematococcus pluvialis

21 January 2018

1 reference

Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice

21 January 2018

1 reference

Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice

21 January 2018

1 reference

Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice

21 January 2018

1 reference

Inhibition of low-density lipoprotein oxidation by astaxanthin.

21 January 2018

1 reference

Antihypertensive and neuroprotective effects of astaxanthin in experimental animals

21 January 2018

1 reference

Plasma appearance and distribution of astaxanthin E/Z and R/S isomers in plasma lipoproteins of men after single dose administration of astaxanthin.

21 January 2018

1 reference

Oral bioavailability of the antioxidant astaxanthin in humans is enhanced by incorporation of lipid based formulations

21 January 2018

1 reference

Plasma appearance of unesterified astaxanthin geometrical E/Z and optical R/S isomers in men given single doses of a mixture of optical 3 and 3'R/S isomers of astaxanthin fatty acyl diesters.

21 January 2018

1 reference

Bioavailability of astaxanthin stereoisomers from wild (Oncorhynchus spp.) and aquacultured (Salmo salar) salmon in healthy men: a randomised, double-blind study.

21 January 2018

1 reference

The in vitro effects of Xancor, a synthetic astaxanthine derivative, on hemostatic biomarkers in aspirin-naïve and aspirin-treated subjects with multiple risk factors for vascular disease

21 January 2018

1 reference

Effect of astaxanthin supplementation on inflammation and cardiac function in BALB/c mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Effect of astaxanthin in combination with alpha-tocopherol or ascorbic acid against oxidative damage in diabetic ODS rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Dietary carotenoids and risk of coronary artery disease in women

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Effect of astaxanthin on the hepatotoxicity, lipid peroxidation and antioxidative enzymes in the liver of CCl4-treated rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083660

Astaxanthin, a carotenoid without vitamin A activity, augments antibody responses in cultures including T-helper cell clones and suboptimal doses of antigen

26 October 2018

1 reference

12 December 2020

The Effects of Vitamin C Supplementation on Protein Oxidation in Healthy Volunteers

1 reference

12 December 2020

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

1 reference

12 December 2020

Serum carotenoids and coronary heart disease. The Lipid Research Clinics Coronary Primary Prevention Trial and Follow-up Study

1 reference

12 December 2020

Effects of astaxanthin supplementation on lipid peroxidation

1 reference

12 December 2020

Vitamin E supplementation and cardiovascular events in high-risk patients

1 reference

12 December 2020

Differential effects of carotenoids on lipid peroxidation due to membrane interactions: X-ray diffraction analysis

1 reference

12 December 2020

Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): randomised placebo-controlled trial

1 reference

12 December 2020

Gastric inflammatory markers and interleukins in patients with functional dyspepsia treated with astaxanthin

1 reference

12 December 2020

Beta-carotene supplementation and incidence of cancer and cardiovascular disease: the Women's Health Study

1 reference

12 December 2020

Serum vitamins, carotenoids, and angina pectoris: findings from the National Health and Nutrition Examination Survey III

1 reference

12 December 2020

Identifiers

DOI

10.3390/MD9030447

1 reference

3 August 2017

1 reference

3 August 2017

1 reference