(Q34631418)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12000608%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

review article

1 reference

title

Exploiting current understanding of antibiotic action for discovery of new drugs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12000608%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

Hesse L

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12000608%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

publication date

1 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12000608%20AND%20SRC:MED&resulttype=core&format=json

Journal of Applied Microbiology

8 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12000608%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

volume

92 Suppl

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12000608%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

4S-15S

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12000608%20AND%20SRC:MED&resulttype=core&format=json

Specificity of the uridine-diphosphate-N-acetylmuramyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate synthetase from Escherichia coli.

8 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Initiation by the DNA-dependent RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

New agents for Gram-positive bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Will genomics revolutionize antimicrobial drug discovery?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Emergent antibiotic resistance: health risks and economic impact

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Protein synthesis as a target for antibacterial drugs: current status and future opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Recent progress in novel macrolides, quinolones, and 2-pyridones to overcome bacterial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Changing patterns of infectious disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Inactivation of antibiotics and the dissemination of resistance genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

RNA polymerase: structural similarities between bacterial RNA polymerase and eukaryotic RNA polymerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Comparative studies of RNA polymerase subunits from various bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Searching for drug targets in microbial genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Design, synthesis, and X-ray crystal structure of a potent dual inhibitor of thymidylate synthase and dihydrofolate reductase as an antitumor agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Crystal structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-diaminopimelate ligase from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

In vitro and in vivo antibacterial activities of TAK-083, an agent for treatment of Helicobacter pylori infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

New strategies for antibacterial drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

DNA gyrase as a drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Bacterial RNA polymerase subunit and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Interaction of antibiotics with functional sites in 16S ribosomal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

RNA polymerase inhibitors with activity against rifampin-resistant mutants of Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Antimicrobial properties and mode of action of the pyrrothine holomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Direct localization of a beta-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Harnessing the power of the genome in the search for new antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

RNA polymerase structure-function: insights into points of transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

The beta subunit Rif-cluster I is only angstroms away from the active center of Escherichia coli RNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Mechanism of action of the oxazolidinone antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Discovery and development of new antibiotics: the problem of antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Drug target validation: lethal infection blocked by inducible peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Dihydropteroate synthase: an old drug target revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

A simple screen for murein transglycosylase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

New antifolate 4,4'-diaminodiphenyl sulfone substituted 2,4-diamino-5-benzylpyrimidines. Proof of their dual mode of action and autosynergism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Crystal structure of Escherichia coli UDPMurNAc-tripeptide d-alanyl-d-alanine-adding enzyme (MurF) at 2.3 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Relationship between antimycobacterial activities of rifampicin, rifabutin and KRM-1648 and rpoB mutations of Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X

Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2672.92.5S1.13.X