(Q34632063)

3 August 2017

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title

New hope for an AIDS vaccine (English)

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3 August 2017

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Harriet L Robinson

1

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publication date

1 April 2002

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Nature Reviews Immunology

3 August 2017

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3 August 2017

2

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3 August 2017

239-250

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3 August 2017

4

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Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

3 August 2017

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Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

21 January 2018

1 reference

Complete nucleotide sequence of the AIDS virus, HTLV-III

21 January 2018

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Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

21 January 2018

1 reference

Energetics of the HIV gp120-CD4 binding reaction

21 January 2018

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Viral dynamics in HIV-1 infection.

21 January 2018

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Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

21 January 2018

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The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy.

21 January 2018

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Multiple sites in HIV-1 reverse transcriptase associated with virological response to combination therapy.

21 January 2018

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Evolutionary and immunological implications of contemporary HIV-1 variation.

21 January 2018

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Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

21 January 2018

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

21 January 2018

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Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.

21 January 2018

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Cellular immune responses to HIV.

21 January 2018

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Controlling HIV pathogenesis: the role of the noncytotoxic anti-HIV response of CD8+ T cells

21 January 2018

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Multifactorial nature of noncytolytic CD8+ T cell-mediated suppression of HIV replication: beta-chemokine-dependent and -independent effects

21 January 2018

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Inhibition of HIV-1 infection by the beta-chemokine MDC

21 January 2018

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Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

21 January 2018

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Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

21 January 2018

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Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

21 January 2018

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Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

21 January 2018

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Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

21 January 2018

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Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques

21 January 2018

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Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.

21 January 2018

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Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity

21 January 2018

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Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination

21 January 2018

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Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

21 January 2018

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Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group

21 January 2018

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Construction of poxviruses as cloning vectors: insertion of the thymidine kinase gene from herpes simplex virus into the DNA of infectious vaccinia virus

21 January 2018

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Vaccinia virus: a selectable eukaryotic cloning and expression vector

21 January 2018

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Genetic immunization is a simple method for eliciting an immune response

21 January 2018

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Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA.

21 January 2018

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Heterologous protection against influenza by injection of DNA encoding a viral protein

21 January 2018

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First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response

21 January 2018

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Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice.

21 January 2018

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Increased expression and immunogenicity of sequence-modified human immunodeficiency virus type 1 gag gene

21 January 2018

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Human immunodeficiency virus type 1-specific immunity after genetic immunization is enhanced by modification of Gag and Pol expression

21 January 2018

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Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection

21 January 2018

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Cationic microparticles: A potent delivery system for DNA vaccines

21 January 2018

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Increased DNA vaccine delivery and immunogenicity by electroporation in vivo

21 January 2018

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Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles

21 January 2018

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An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants

21 January 2018

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Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus

21 January 2018

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Production of recombinant adeno-associated virus vectors using a packaging cell line and a hybrid recombinant adenovirus

21 January 2018

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Engineering poliovirus as a vaccine vector for the expression of diverse antigens

21 January 2018

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Mucosal and systemic HIV-1 Env-specific CD8(+) T-cells develop after intragastric vaccination with a Salmonella Env DNA vaccine vector.

21 January 2018

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The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopoxviruses

21 January 2018

1 reference

Modified vaccinia virus Ankara undergoes limited replication in human cells and lacks several immunomodulatory proteins: implications for use as a human vaccine

21 January 2018

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Repression of the interferon signal transduction pathway by the adenovirus E1A oncogene

21 January 2018

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"E3/19K" protein of adenovirus type 2 inhibits lysis of cytolytic T lymphocytes by blocking cell-surface expression of histocompatibility class I antigens

21 January 2018

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A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor

21 January 2018

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Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line

21 January 2018

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New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses.

21 January 2018

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Nonreplicating vaccinia vector efficiently expresses recombinant genes

21 January 2018

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A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia

21 January 2018

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Replication-defective vector based on a chimpanzee adenovirus

21 January 2018

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Induction of CD8+ T cells using heterologous prime-boost immunisation strategies

21 January 2018

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The prime-boost strategy: exciting prospects for improved vaccination

21 January 2018

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Priming with recombinant influenza virus followed by administration of recombinant vaccinia virus induces CD8+ T-cell-mediated protective immunity against malaria

21 January 2018

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Neutralizing antibody-independent containment of immunodeficiency virus challenges by DNA priming and recombinant pox virus booster immunizations

21 January 2018

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Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination.

21 January 2018

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DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations

21 January 2018

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Tuberculosis DNA vaccine encoding Ag85A is immunogenic and protective when administered by intramuscular needle injection but not by epidermal gene gun bombardment

21 January 2018

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Comparative efficacy of recombinant modified vaccinia virus Ankara expressing simian immunodeficiency virus (SIV) Gag-Pol and/or Env in macaques challenged with pathogenic SIV

21 January 2018

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ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency

21 January 2018

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The dynamics of the cellular immune response to HIV infection: implications for vaccination

21 January 2018

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Sexual transmission of HIV.

21 January 2018

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Genetic and immunologic characterization of viruses infecting MN-rgp120-vaccinated volunteers

21 January 2018

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Safety of 2 recombinant human immunodeficiency virus type 1 (HIV-1) envelope vaccines in neonates born to HIV-1-infected women

21 January 2018

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Design and construction of an experimental HIV-1 vaccine for a year-2000 clinical trial in Kenya.

21 January 2018

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Biology of attenuated modified vaccinia virus Ankara recombinant vector in mice: virus fate and activation of B- and T-cell immune responses in comparison with the Western Reserve strain and advantages as a vaccine

21 January 2018

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Potentiation of simian immunodeficiency virus (SIV)-specific CD4(+) and CD8(+) T cell responses by a DNA-SIV and NYVAC-SIV prime/boost regimen

21 January 2018

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Applications of pox virus vectors to vaccination: an update

21 January 2018

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Induction of immune responses to HIV-1 by canarypox virus (ALVAC) HIV-1 and gp120 SF-2 recombinant vaccines in uninfected volunteers. NIAID AIDS Vaccine Evaluation Group

21 January 2018

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Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectors

21 January 2018

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HIV-1 gag proteins: diverse functions in the virus life cycle

21 January 2018

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Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

21 January 2018

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Protection from pathogenic SIV challenge using multigenic DNA vaccines

21 January 2018

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Reverse transcriptase fidelity and HIV-1 variation

21 January 2018

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CD8+ cells in human immunodeficiency virus type I pathogenesis: cytolytic and noncytolytic inhibition of viral replication.

31 March 2020

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CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.

31 March 2020

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Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination

31 March 2020

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Modulating the immune response to genetic immunization

31 March 2020

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Compact, synthetic, vaccinia virus early/late promoter for protein expression.

31 March 2020

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Presentation of SIVgag to monkey T cells using dendritic cells transfected with a recombinant adenovirus

31 March 2020

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Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model

31 March 2020

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AIDS vaccine models: challenging challenge viruses

31 March 2020

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Highly attenuated poxvirus vectors

31 March 2020

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Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys

31 March 2020

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7 January 2021

Adenovirus early region 1A modulation of interferon antiviral activity

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7 January 2021

Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products

1 reference

7 January 2021

Simian immunodeficiency virus DNA vaccine trial in macaques.

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7 January 2021

Identifiers

DOI

10.1038/NRI776

1 reference

3 August 2017

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PubMed ID

12001995