(Q34632089)

3 August 2017

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title

The quest for an AIDS vaccine: is the CD8+ T-cell approach feasible? (English)

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3 August 2017

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Andrew James McMichael

series ordinal

1

object named as

Andrew McMichael

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3 August 2017

Tomâs Hanke

2

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3 August 2017

1 April 2002

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Nature Reviews Immunology

3 August 2017

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3 August 2017

2

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3 August 2017

4

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3 August 2017

283-291

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Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibody

3 August 2017

1 reference

Fine analysis of humoral antibody response to envelope glycoprotein of SIV in infected and vaccinated macaques.

21 January 2018

1 reference

The antigenic structure of the HIV gp120 envelope glycoprotein

21 January 2018

1 reference

Passive immunization with a human monoclonal antibody protects hu-PBL-SCID mice against challenge by primary isolates of HIV-1.

21 January 2018

1 reference

HIV-1 neutralizing antibodies: how full is the bottle?

21 January 2018

1 reference

gp120: Biologic aspects of structural features

21 January 2018

1 reference

Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

21 January 2018

1 reference

Phenotypic analysis of antigen-specific T lymphocytes

21 January 2018

1 reference

Rapid effector function in CD8+ memory T cells

21 January 2018

1 reference

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

21 January 2018

1 reference

Large clonal expansions of CD8+ T cells in acute infectious mononucleosis

21 January 2018

1 reference

CD8(+) T-cell selection, function, and death in the primary immune response in vivo

21 January 2018

1 reference

HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function

21 January 2018

1 reference

Skewed maturation of memory HIV-specific CD8 T lymphocytes

21 January 2018

1 reference

Cytotoxic T-cell memory without antigen

21 January 2018

1 reference

Stimulation of memory T cells by cytokines

21 January 2018

1 reference

Antivirally protective cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by persisting antigen

21 January 2018

1 reference

T cell memory. Long-term persistence of virus-specific cytotoxic T cells

21 January 2018

1 reference

The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

21 January 2018

1 reference

Viral immune evasion due to persistence of activated T cells without effector function

21 January 2018

1 reference

High-affinity T helper epitope induces complementary helper and APC polarization, increased CTL, and protection against viral infection

21 January 2018

1 reference

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

21 January 2018

1 reference

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions.

21 January 2018

1 reference

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

21 January 2018

1 reference

T cell responses and viral escape

21 January 2018

1 reference

Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

21 January 2018

1 reference

Functionally inert HIV-specific cytotoxic T lymphocytes do not play a major role in chronically infected adults and children

21 January 2018

1 reference

Triple therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer disease: results of a multicentre study in South-East Asia. South-East Asia Multicenter Study Group.

21 January 2018

1 reference

The dynamics of the cellular immune response to HIV infection: implications for vaccination

21 January 2018

1 reference

Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection

21 January 2018

1 reference

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

21 January 2018

1 reference

Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

21 January 2018

1 reference

Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

21 January 2018

1 reference

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

21 January 2018

1 reference

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

21 January 2018

1 reference

Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef.

21 January 2018

1 reference

Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

21 January 2018

1 reference

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

21 January 2018

1 reference

Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi

21 January 2018

1 reference

Absence of specific mucosal antibody responses in HIV-exposed uninfected sex workers from the Gambia

21 January 2018

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CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects

21 January 2018

1 reference

Human immunodeficiency virus (HIV)-specific cytotoxic T lymphocyte activity in HIV-exposed seronegative persons

21 January 2018

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ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids

21 January 2018

1 reference

Factors contributing to the lack of human immunodeficiency virus type 1 (HIV-1) transmission in HIV-1-discordant partners.

21 January 2018

1 reference

Containment of simian immunodeficiency virus infection: cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment

21 January 2018

1 reference

Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.

21 January 2018

1 reference

An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants

21 January 2018

1 reference

Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity

21 January 2018

1 reference

Cross-protection and cross-reactive cytotoxic T cells induced by influenza virus vaccines in mice

21 January 2018

1 reference

Immunogenicity of the yeast recombinant p17/p24:Ty virus-like particles (p24-VLP) in healthy volunteers

21 January 2018

1 reference

T cell priming versus T cell tolerance induced by synthetic peptides

21 January 2018

1 reference

Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses.

21 January 2018

1 reference

Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

21 January 2018

1 reference

Heterologous protection against influenza by injection of DNA encoding a viral protein

21 January 2018

1 reference

Enhancement of MHC class I-restricted peptide-specific T cell induction by a DNA prime/MVA boost vaccination regime

21 January 2018

1 reference

Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara

21 January 2018

1 reference

Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers.

21 January 2018

1 reference

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine.

21 January 2018

1 reference

First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response

21 January 2018

1 reference

Safety and immune responses to a DNA-based human immunodeficiency virus (HIV) type I env/rev vaccine in HIV-infected recipients: follow-up data

21 January 2018

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Vaccination of seronegative volunteers with a human immunodeficiency virus type 1 env/rev DNA vaccine induces antigen-specific proliferation and lymphocyte production of beta-chemokines

21 January 2018

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Cellular cytotoxic response induced by DNA vaccination in HIV-1-infected patients.

21 January 2018

1 reference

Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes

21 January 2018

1 reference

Recombinant vaccinia virus primes and stimulates influenza haemagglutinin-specific cytotoxic T cells

21 January 2018

1 reference

Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group

21 January 2018

1 reference

Induction of human immunodeficiency virus type 1 (HIV-1)-specific cytolytic T lymphocyte responses in seronegative adults by a nonreplicating, host-range-restricted canarypox vector (ALVAC) carrying the HIV-1MN env gene

21 January 2018

1 reference

Vaccination of vaccinia-naive adults with human immunodeficiency virus type 1 gp160 recombinant vaccinia virus in a blinded, controlled, randomized clinical trial. The AIDS Vaccine Clinical Trials Network

21 January 2018

1 reference

A group specific anamnestic immune reaction against HIV-1 induced by a candidate vaccine against AIDS.

21 January 2018

1 reference

An algorithm for evaluating human cytotoxic T lymphocyte responses to candidate AIDS vaccines.

21 January 2018

1 reference

Potentiation of simian immunodeficiency virus (SIV)-specific CD4(+) and CD8(+) T cell responses by a DNA-SIV and NYVAC-SIV prime/boost regimen

21 January 2018

1 reference

MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA) (author's transl)

21 January 2018

1 reference

Reduction of simian-human immunodeficiency virus 89.6P viremia in rhesus monkeys by recombinant modified vaccinia virus Ankara vaccination

21 January 2018

1 reference

Induction of mucosal homing virus-specific CD8(+) T lymphocytes by attenuated simian immunodeficiency virus

21 January 2018

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Gene gun-based nucleic acid immunization alone or in combination with recombinant vaccinia vectors suppresses virus burden in rhesus macaques challenged with a heterologous SIV.

21 January 2018

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Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen

21 January 2018

1 reference

HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.

21 January 2018

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Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses

21 January 2018

1 reference

The organization of human leucocyte antigen class I epitopes in HIV genome products: implications for HIV evolution and vaccine design

21 January 2018

1 reference

T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen

21 January 2018

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Cytotoxic T-cell activity antagonized by naturally occurring HIV-1 Gag variants

21 January 2018

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Antagonist HIV-1 Gag peptides induce structural changes in HLA B8

21 January 2018

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Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

21 January 2018

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Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

21 January 2018

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Evolutionary and immunological implications of contemporary HIV-1 variation.

21 January 2018

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Evolution and transmission of stable CTL escape mutations in HIV infection

21 January 2018

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Protective cytotoxic T lymphocyte responses against paramyxoviruses induced by epitope-based DNA vaccines: involvement of IFN-gamma.

21 January 2018

1 reference

Immunization with a modified vaccinia virus expressing simian immunodeficiency virus (SIV) Gag-Pol primes for an anamnestic Gag-specific cytotoxic T-lymphocyte response and is associated with reduction of viremia after SIV challenge

21 January 2018

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Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

21 January 2018

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Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

21 January 2018

1 reference

Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques

21 January 2018

1 reference

Gulf Stream shifts following ENSO events

21 January 2018

1 reference

HIV-specific cytotoxic T lymphocytes in seropositive individuals

21 January 2018

1 reference

Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes

21 January 2018

1 reference

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

21 January 2018

1 reference

Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor

31 March 2020

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Direct visualization of HIV-1-specific cytotoxic T lymphocytes during primary infection.

31 March 2020

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Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression

31 March 2020

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Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

31 March 2020

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HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant

31 March 2020

1 reference

Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination

31 March 2020

1 reference

Retrospective analysis of viral load and SIV antibody responses in rhesus macaques infected with pathogenic SIV: predictive value for disease progression

31 March 2020

1 reference

DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans

31 March 2020

1 reference

New prospects for the development of a vaccine against human immunodeficiency virus type 1. An overview

31 March 2020

1 reference

Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques

31 March 2020

1 reference

Characterization of HIV-1-specific T-helper cells in acute and chronic infection

31 March 2020

1 reference

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

31 March 2020

1 reference

7 January 2021

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

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7 January 2021

Selection of virus variants and emergence of virus escape mutants after immunization with an epitope vaccine.

1 reference

7 January 2021

The cytolytic activity of pulmonary CD8+ lymphocytes, induced by infection with a vaccinia virus recombinant expressing the M2 protein of respiratory syncytial virus (RSV), correlates with resistance to RSV infection in mice.

1 reference

7 January 2021

Protective cellular immunity: cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization

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7 January 2021

DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction

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7 January 2021

Identifiers

DOI

10.1038/NRI779

1 reference

release_2whjy4hy7vhx3bby6uxktseipm

3 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2whjy4hy7vhx3bby6uxktseipm

24 November 2022

mapped directly with Wikidata item

PubMed ID

12001999

1 reference

PubMed ID

12001999