(Q34632456)

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Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNA (English)

1 reference

Europe PubMed Central

3 August 2017

0 references

author name string

Kuwabara T

1

1 reference

Europe PubMed Central

3 August 2017

Warashina M

2

1 reference

Europe PubMed Central

3 August 2017

Tanabe T

3

1 reference

Europe PubMed Central

3 August 2017

Tani K

4

1 reference

Europe PubMed Central

3 August 2017

Asano S

5

1 reference

Europe PubMed Central

3 August 2017

Taira K

6

1 reference

Europe PubMed Central

3 August 2017

language of work or name

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publication date

1 August 1997

1 reference

Europe PubMed Central

3 August 2017

number of pages

8

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based on heuristic

inferred from page(s)

Nucleic Acids Research

1 reference

Europe PubMed Central

3 August 2017

25

1 reference

Europe PubMed Central

3 August 2017

15

1 reference

Europe PubMed Central

3 August 2017

3074-3081

1 reference

Europe PubMed Central

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

The structure, function and application of the hammerhead ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Observations on catalysis by hammerhead ribozymes are consistent with a two-divalent-metal-ion mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

A general purpose RNA-cleaving DNA enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Multi-unit anti-BCR-ABL ribozyme therapy in chronic myelogenous leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Selection of the best target site for ribozyme-mediated cleavage within a fusion gene for adenovirus E1A-associated 300 kDa protein (p300) and luciferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozymes: structure and mechanism in RNA catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Therapeutic applications of ribozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Kinetic selectivity of complementary nucleic acids: bcr-abl-directed antisense RNA and ribozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Specificity of hammerhead ribozyme cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Dependence on Mg2+ ions of the activities of dimeric hammerhead minizymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

The basic science of gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

How many catalytic RNAs? Ions and the Cheshire cat conjecture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Theoretical analyses on the role of Mg2+ ions in ribozyme reactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Metal ion catalysis in the Tetrahymena ribozyme reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozyme-mediated cleavage of the BCRABL oncogene transcript: in vitro cleavage of RNA and in vivo loss of P210 protein-kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

A general two-metal-ion mechanism for catalytic RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Comparison of different ribozymes for efficient and specific cleavage of BCR/ABL related mRNAs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

RNA enzyme-directed gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Three-dimensional structure of a hammerhead ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Multiple domains in a ribozyme construct confer increased suppressive activity in monkey cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozyme-mediated cleavage of the MDR-1 transcript restores chemosensitivity in previously resistant cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozymes as human therapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Comparative analysis of cleavage rates after systematic permutation of the NUX consensus target motif for hammerhead ribozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozymes: a distinct class of metalloenzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Resistance to human immunodeficiency virus type 1 infection conferred by transduction of human peripheral blood lymphocytes with ribozyme, antisense, or polymeric trans-activation response element constructs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozymes: biology, biochemistry, and implications for clinical medicine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Inhibition of gene expression with ribozymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Improved accumulation and activity of ribozymes expressed from a tRNA-based RNA polymerase III promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozymes in gene therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

RNA cleavage by small catalytic RNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1 reference

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7 July 2018

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Self-cleavage of RNA in the replication of small pathogens of plants and animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Ribozymes as potential anti-HIV-1 therapeutic agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

7 July 2018

Sequence requirements of the hammerhead RNA self-cleavage reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=146844

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Simple RNA enzymes with new and highly specific endoribonuclease activities

1 reference

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26 October 2018

A small catalytic oligoribonucleotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

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Cleavage of specific sites of RNA by designed ribozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

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Energetics of RNA cleavage: implications for the mechanism of action of ribozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

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Extended target-site specificity for a hammerhead ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human gene therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

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In vitro and in vivo effects of synthetic ribozymes targeted against BCR/ABL mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the role of solvated metal hydroxide in the hammerhead cleavage mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

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Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ribozyme-mediated cleavage of the bcr/abl transcript expressed in chronic myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generality of the NUX rule: kinetic analysis of the results of systematic mutations in the trinucleotide at the cleavage site of hammerhead ribozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

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Improved specificity of ribozyme-mediated cleavage of bcr-abl mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of substrate structure on cleavage by hammerhead ribozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

12 December 2020

based on heuristic

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Investigating and improving the specificity of ribozymes directed against the bcr-abl translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

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Cell cycle arrest promotes trans-hammerhead ribozyme action in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/9224607

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Catalytic activities of hammerhead ribozymes with a triterpenoid linker instead of stem/loop II

1 reference

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Identifiers

10.1093/NAR/25.15.3074

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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