(Q34632510)

3 August 2017

title

Empty Virions In AAV8 Vector Preparations Reduce Transduction Efficiency And May Cause Total Viral Particle Dose-Limiting Side-Effects (English)

1 reference

3 August 2017

1 reference

Kai Gao

1

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3 August 2017

Mengxin Li

2

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3 August 2017

Li Zhong

3

1 reference

3 August 2017

Qin Su

4

1 reference

3 August 2017

Jia Li

5

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3 August 2017

Shaoyong Li

6

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3 August 2017

Ran He

7

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3 August 2017

Yu Zhang

8

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3 August 2017

Gregory Hendricks

9

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3 August 2017

Junzhi Wang

10

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3 August 2017

Guangping Gao

11

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3 August 2017

publication date

1 January 2014

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Molecular Therapy. Methods & Clinical Development

3 August 2017

published in

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3 August 2017

volume

1

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3 August 2017

issue

9

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3 August 2017

page(s)

20139

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describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4255953/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Overcoming preexisting humoral immunity to AAV using capsid decoys

7 July 2018

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A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice.

7 July 2018

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CpG-depleted adeno-associated virus vectors evade immune detection.

7 July 2018

1 reference

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Gene transfer in the liver using recombinant adeno-associated virus

7 July 2018

1 reference

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Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical

7 July 2018

1 reference

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Adeno-associated virus capsid antigen presentation is dependent on endosomal escape

7 July 2018

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Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid trafficking

7 July 2018

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Production and discovery of novel recombinant adeno-associated viral vectors

7 July 2018

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Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

7 July 2018

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Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primates

7 July 2018

1 reference

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Good manufacturing practice production of self-complementary serotype 8 adeno-associated viral vector for a hemophilia B clinical trial

7 July 2018

1 reference

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Assessing the potential for AAV vector genotoxicity in a murine model

7 July 2018

1 reference

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BALB/c mice show impaired hepatic tolerogenic response following AAV gene transfer to the liver

7 July 2018

1 reference

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Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver.

7 July 2018

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Analytical ultracentrifugation: sedimentation velocity and sedimentation equilibrium

7 July 2018

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

7 July 2018

1 reference

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New recombinant serotypes of AAV vectors.

7 July 2018

1 reference

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Rate limiting steps of AAV transduction and implications for human gene therapy.

7 July 2018

1 reference

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Obstacles to human hematopoietic stem cell transduction by recombinant adeno-associated virus 2 vectors.

7 July 2018

1 reference

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Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

7 July 2018

1 reference

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Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector

7 July 2018

1 reference

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Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector

7 July 2018

1 reference

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Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells

7 July 2018

1 reference

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High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255953

Determination of particle heterogeneity and stability of recombinant adenovirus by analytical ultracentrifugation in CsCl gradients

26 October 2018

1 reference

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CD8(+) T-cell responses to adeno-associated virus capsid in humans

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255953

Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255953

No evidence for tumorigenesis of AAV vectors in a large-scale study in mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255953

26 October 2018

Identifiers

DOI

10.1038/MTM.2013.9

1 reference

3 August 2017

1 reference

3 August 2017

1 reference