(Q34632817)

English

Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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author name string

Eduardo C Filippi-Chiela

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Marcos Paulo Thomé

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Mardja Manssur Bueno e Silva

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Alessandra Luíza Pelegrini

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Pitia Flores Ledur

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Bernardo Garicochea

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Lauren L Zamin

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Guido Lenz

8

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Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

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publication date

22 March 2013

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Europe PubMed Central

PubMed publication ID

3 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

13

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Europe PubMed Central

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3 August 2017

147

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

https://scigraph.springernature.com/pub.10.1186/1471-2407-13-147

0 references

Nuclear morphometric analysis (NMA): screening of senescence, apoptosis and nuclear irregularities.

1 reference

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7 July 2018

Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway

1 reference

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7 July 2018

Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy

1 reference

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7 July 2018

Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells

1 reference

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7 July 2018

In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma

1 reference

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Nek1 silencing slows down DNA repair and blocks DNA damage-induced cell cycle arrest

1 reference

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Survival comparison between glioblastoma multiforme and other incurable cancers

1 reference

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7 July 2018

Methods in mammalian autophagy research

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7 July 2018

Celastrol synergistically enhances temozolomide cytotoxicity in melanoma cells

1 reference

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7 July 2018

The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Antifolate activity of pyrimethamine enhances temozolomide-induced cytotoxicity in melanoma cells

1 reference

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7 July 2018

Resveratrol: its biologic targets and functional activity

1 reference

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7 July 2018

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

1 reference

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Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint

1 reference

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7 July 2018

Death through a tragedy: mitotic catastrophe

1 reference

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In vitro and in vivo radiosensitization induced by the DNA methylating agent temozolomide

1 reference

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7 July 2018

Take a break--resveratrol in action on DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Proautophagic drugs: a novel means to combat apoptosis-resistant cancers, with a special emphasis on glioblastomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Malignant astrocytic glioma: genetics, biology, and paths to treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Temozolomide induces senescence but not apoptosis in human melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Human glioblastoma U87MG cells transduced with a dominant negative p53 (TP53) adenovirus construct undergo radiation-induced mitotic catastrophe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Cdc25 and Wee1: analogous opposites?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Cyclin B1-Cdk1 activation continues after centrosome separation to control mitotic progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Genetic pathways to primary and secondary glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Mechanisms involved in resveratrol-induced apoptosis and cell cycle arrest in prostate cancer-derived cell lines

1 reference

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7 July 2018

c-Myc downregulation: a critical molecular event in resveratrol-induced cell cycle arrest and apoptosis of human medulloblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

The reversibility of mitotic exit in vertebrate cells

1 reference

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7 July 2018

Modulation of chemotherapy resistance in regional therapy: a novel therapeutic approach to advanced extremity melanoma using intra-arterial temozolomide in combination with systemic O6-benzylguanine

1 reference

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7 July 2018

O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Signalling cell cycle arrest and cell death through the MMR System

1 reference

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7 July 2018

Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence

1 reference

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7 July 2018

Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype

1 reference

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7 July 2018

Resveratrol-induced apoptotic death in human U251 glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

MGMT gene silencing and benefit from temozolomide in glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Cell death by mitotic catastrophe: a molecular definition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe

1 reference

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A randomized phase I and pharmacological trial of sequences of 1,3-bis(2-chloroethyl)-1-nitrosourea and temozolomide in patients with advanced solid neoplasms

1 reference

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7 July 2018

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

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Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

Anti-leukemia effect of resveratrol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

7 July 2018

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

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Resveratrol induces colon tumor cell apoptosis independently of p53 and precede by epithelial differentiation, mitochondrial proliferation and membrane potential collapse

1 reference

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A silver staining method for single-cell gel assay

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Positive regulation of Wee1 by Chk1 and 14-3-3 proteins

1 reference

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Dual antitumor effects of 5-fluorouracil on the cell cycle in colorectal carcinoma cells: a novel target mechanism concept for pharmacokinetic modulating chemotherapy.

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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Role of pRB dephosphorylation in cell cycle regulation

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1 reference

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7 July 2018

Resveratrol arrests the cell division cycle at S/G2 phase transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3635906

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

1 reference

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Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

1 reference

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Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

1 reference

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7 July 2018

Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.

1 reference

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Quantification of O6-methylguanine-DNA methyltransferase mRNA in human brain tumors.

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Specific enzymatic dephosphorylation of the retinoblastoma protein

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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A simple technique for quantitation of low levels of DNA damage in individual cells

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Protective effect of resveratrol against oxygen-glucose deprivation in organotypic hippocampal slice cultures: Involvement of PI3-K pathway.

1 reference

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21 January 2018

Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells.

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21 January 2018

Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells

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DNA damage and repair measured in different genomic regions using the comet assay with fluorescent in situ hybridization

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Resveratrol induces prostate cancer cell entry into s phase and inhibits DNA synthesis.

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p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells

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The single cell microgel electrophoresis assay (comet assay): technical aspects and applications. Report on the 5th LH Gray Trust Workshop, Institute of Cancer Research, 1994

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inferred from PubMed ID database lookup

Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2407-13-147

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

ResearchGate publication ID

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