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miR-34 - a microRNA replacement therapy is headed to the clinic
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
title
miR-34 - a microRNA replacement therapy is headed to the clinic
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
main subject
microRNA
1 reference
based on heuristic
inferred from title
author name string
Andreas G Bader
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
publication date
2 July 2012
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
published in
Frontiers in Genetics
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
volume
3
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
page(s)
120
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
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MicroRNA-34a inhibits the proliferation and metastasis of osteosarcoma cells both in vitro and in vivo
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Hypoxia-induced down-regulation of microRNA-34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells
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MicroRNA-34a affects the occurrence of laryngeal squamous cell carcinoma by targeting the antiapoptotic gene survivin
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MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma
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MicroRNA-34a targets notch1 and inhibits cell proliferation in glioblastoma multiforme
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MiR-34a chemosensitizes bladder cancer cells to cisplatin treatment regardless of p53-Rb pathway status
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Regulation of cancer aggressive features in melanoma cells by microRNAs
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7 July 2018
Myc-mediated repression of microRNA-34a promotes high-grade transformation of B-cell lymphoma by dysregulation of FoxP1
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7 July 2018
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice
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The rno-miR-34 family is upregulated and targets ACSL1 in dimethylnitrosamine-induced hepatic fibrosis in rats
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Regulation of Axl receptor tyrosine kinase expression by miR-34a and miR-199a/b in solid cancer
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7 July 2018
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
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7 July 2018
Frequent concomitant inactivation of miR-34a and miR-34b/c by CpG methylation in colorectal, pancreatic, mammary, ovarian, urothelial, and renal cell carcinomas and soft tissue sarcomas
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7 July 2018
Systematic proteome analysis identifies transcription factor YY1 as a direct target of miR-34a
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7 July 2018
miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma
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7 July 2018
Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells
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7 July 2018
The promise of microRNA replacement therapy
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PubMed Central
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7 July 2018
Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy.
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7 July 2018
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
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MicroRNA-34a: a novel tumor suppressor in p53-mutant glioma cell line U251.
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7 July 2018
MicroRNA-34a inhibits cell proliferation by repressing mitogen-activated protein kinase kinase 1 during megakaryocytic differentiation of K562 cells
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7 July 2018
MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
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7 July 2018
Frequent downregulation of miR-34 family in human ovarian cancers
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PubMed Central
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7 July 2018
Epigenetic inactivation of the miR-34a in hematological malignancies
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PubMed Central
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7 July 2018
E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis
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PubMed Central
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7 July 2018
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
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7 July 2018
p53-independent upregulation of miR-34a during oncogene-induced senescence represses MYC.
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7 July 2018
miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53.
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PubMed Central
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7 July 2018
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
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PubMed Central
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7 July 2018
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
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7 July 2018
Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts
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7 July 2018
MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation
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7 July 2018
Analysis of DNA copy number alterations in ovarian serous tumors identifies new molecular genetic changes in low-grade and high-grade carcinomas
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7 July 2018
Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6
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7 July 2018
miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities
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7 July 2018
MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met.
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7 July 2018
miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells
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7 July 2018
Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet
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7 July 2018
Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells
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7 July 2018
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
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7 July 2018
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
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7 July 2018
An integrated genomic analysis of human glioblastoma multiforme
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7 July 2018
A microRNA DNA methylation signature for human cancer metastasis
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7 July 2018
miR-34a repression of SIRT1 regulates apoptosis
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7 July 2018
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
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7 July 2018
Widespread changes in protein synthesis induced by microRNAs
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PubMed Central
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7 July 2018
A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene
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PubMed Central
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7 July 2018
The MYCN oncogene is a direct target of miR-34a
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7 July 2018
Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest
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7 July 2018
The let-7 microRNA reduces tumor growth in mouse models of lung cancer
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7 July 2018
Suppression of non-small cell lung tumor development by the let-7 microRNA family
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7 July 2018
miRNAMap 2.0: genomic maps of microRNAs in metazoan genomes
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7 July 2018
Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
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7 July 2018
p53-mediated activation of miRNA34 candidate tumor-suppressor genes.
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7 July 2018
A microRNA component of the p53 tumour suppressor network
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7 July 2018
Erlotinib: success of a molecularly targeted agent for the treatment of advanced pancreatic cancer
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7 July 2018
Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
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PubMed Central
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7 July 2018
Transcriptional activation of miR-34a contributes to p53-mediated apoptosis
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7 July 2018
MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387671
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7 July 2018
RAS is regulated by the let-7 microRNA family
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7 July 2018
Yin Yang 1 is a negative regulator of p53.
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PubMed Central
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7 July 2018
The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website
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PubMed Central
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7 July 2018
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
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PubMed Central
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7 July 2018
Stem cells, cancer, and cancer stem cells
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PubMed Central
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7 July 2018
Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387671
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26 October 2018
A p53-inducible microRNA-34a downregulates Ras signaling by targeting IMPDH.
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26 October 2018
MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms
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26 October 2018
Reduced miR-34a expression in normal cervical tissues and cervical lesions with high-risk human papillomavirus infection.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387671
retrieved
26 October 2018
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387671
retrieved
26 October 2018
Reduced levels of miR-34a in neuroblastoma are not caused by mutations in the TP53 binding site.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387671
retrieved
26 October 2018
Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3387671
retrieved
26 October 2018
microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22783274
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FGENE.2012.00120
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
PMCID
3387671
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
PubMed ID
22783274
1 reference
stated in
Europe PubMed Central
PubMed ID
22783274
retrieved
3 August 2017
ResearchGate publication ID
229072623
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